Endometrial hyperplasia - a disorder in which the seal of the uterus due to too rapid multiplication of its cells. This is not a malignant disease, but in some women, endometrial hyperplasia can lead to uterine cancer.
Reasons for the development of endometrial hyperplasia
The development of endometrial hyperplasia is often associated with an imbalance between the two female sex hormones - estrogen
Estrogen - the key to bone health
and progesterone
Progesterone - norm and pathology
. Sometimes the body is mostly under the influence of estrogen - progesterone thus produced is very small, or it is not produced at all. This is called estrogen dominance.
An imbalance of hormones can occur for many reasons - for example, it may be due to natural hormonal changes during menopause, taking estrogen replacement drugs for therapy or tamoxifen.
Estrogen replacement therapy is normally assigned only to women who have had a hysterectomy (removal of the uterus). Tamoxifen - a drug used in the treatment of breast cancer; it acts on the uterus as well as estrogen, which is why it can cause the development of hyperplasia.
Types of endometrial hyperplasia
There are two basic types of endometrial hyperplasia:
- Hyperplasia without atypia;
- Atypical hyperplasia.
Each type of hyperplasia can also be simple or complex. When you change the structure of atypical hyperplasia cells and increases the risk of uterine cancer.
How to diagnose hyperplasia
The most common symptom of hyperplasia is abnormal vaginal bleeding. It can be heavy, prolonged menstruation, or bleeding between periods. If you notice unusual bleeding is very important as soon as possible to see a doctor.
If you suspect hyperplasia doctor may prescribe a vaginal ultrasound, hysteroscopy, and other diagnostic procedures.
The risk of uterine cancer
If a woman has no atypical endometrial changes, the likelihood of developing cervical cancer is very low. With these changes in the risk of cancer of the uterus increased. At 1-2 out of 10 women (10-20%) with atypical endometrial hyperplasia
Hyperplasia endometrial cancer - requires timely detection and treatment
this violation turns into cancer of the uterus.
The risk is especially great in cases where the atypical hyperplasia begins to develop after menopause.
Treatment of endometrial hyperplasia
Both types of hyperplasia can be treated. When choosing a method of treatment, the physician must take into account the following:
- The cause of hyperplasia;
- Presence of abnormal changes in the cells;
- Age of the patient (of special importance that occurred or not menopause);
- The desire of the patient to have children in the future;
- General health - can the patient do the operation.
Young women who have not been identified atypical changes that can be assigned to receive synthetic analogues of progesterone to reduce the influence of estrogen on the body. However, if the patient has menopause, and she discovered atypical hyperplasia, your doctor is likely to prescribe surgery - removal of the uterus (hysterectomy) and ovaries.
Hyperplasia and atypical hyperplasia of the breast
Hyperplasia and atypical hyperplasia of the breast - is a benign disease that develops in the breast tissue. In typical cases, they do not cause pain, and any other symptoms. Although hyperplasia is most common in women, and sometimes it affects men (they also have the breast, but normally it is not developed as female).
The mammary gland consists of shares (which is produced by breast milk) and milk ducts (the channels through which milk flows to the nipple). Shares and ducts surrounded by glandular, connective and fatty tissues. Surfaces coated with lobes and ductal epithelial cells. In some cases, these cells begin to multiply excessively active and / or increase in size - a violation is called hyperplasia.
Hyperplasia may develop in the ducts (ductal hyperplasia) or lobes (lobular hyperplasia). There are several forms of hyperplasia - mild to moderate and heavier - depending on how the cells appear under a microscope.
Typically hyperplasia develops naturally in proportion as the structure changes with age of breast cancer. It is common in women of any age, but most patients with this disorder - over 35 years. Sometimes this is also called epithelial hyperplasia giperlaziey or simple hyperplasia.
What is atypical hyperplasia
Atypical hyperplasia is called a disorder in which the cells of the breast tissue is not only very quickly multiply, but also acquire an unusual shape. This violation, as usual hyperplasia, can affect the ducts (atypical ductal hyperplasia) or shares (atypical lobular hyperplasia). Patients with atypical ductal hyperplasia risk of developing breast cancer in the future, a little above the norm.
Atypical lobular hyperplasia, lobular neoplasia, is a form, another benign disease affecting the mammary gland.
Both types of hyperplasia of the breast is usually detected by accident - during a biopsy or surgery on the chest, after which conducted the laboratory analysis of tissue samples.
Treatment
In most cases, hyperplasia does not require any treatment. Usually doctors do not prescribe further examinations, so that the violation has virtually no progress.
If atypical hyperplasia was found through a biopsy, the doctor may prescribe a minimally invasive surgery to completely remove the tumors. An alternative is to vacuum breast biopsy. Before the procedure, the patient is administered a local anesthetic, after which the skin makes a small incision. Therethrough in the breast tissue is administered hollow tube attached to a vacuum device. Guided by the image obtained by ultrasound or mammogram, the doctor removes a vacuum affected by hyperplasia of the breast tissue. With this technology, in most cases it is possible to avoid the use of general anesthesia and invasive surgery. Typically, the patient can go home the same day, when the procedure was performed.
After the procedure, you should regularly undergo a medical examination. Typically, doctors advise patients once in two or three years to do a mammogram - it allows you to monitor further changes in the breast tissue.
Effects
- Hyperplasia of the breast
Hyperplasia does not increase the risk of developing breast cancer in the future, however, the patient should still conduct regular breast self-examination, and immediately contact a doctor if in its structure there will be any changes.
- Atypical hyperplasia of the breast
In women, in whose history there is a violation, the likelihood of breast cancer higher than normal, but it should not become a source of constant stress
How to beat stress? Create an oasis
. The patient has to go to all your doctor's examination, and do not forget to systematically examined in the case of moving to another city or country. Monthly breast self-examination also increases the likelihood of timely diagnosis of cancer - if he did begin to develop.