Behcet's disease occurs genital lesion, but this is only one symptom of the disease. In addition to the genital organs are also affected mucous membranes of the mouth and eyes. The disease was first described by the Turkish dermatologist Behçet in 1937.

What is Behcet's disease

Behcet's disease - a systemic vasculitis Vasculitis - when blood vessels refuse to work Which manifested the characteristic triad of aphthous ulcers of the mucous membranes of the mouth, eyes and genitals. The process also involved joints and internal organs. The disease is chronic recurrent septic allergic in nature and manifests as thrombophlebitis, bleeding in the skin, the appearance of blood in the urine Blood in the urine - a reason for serious concern , Bleeding from the gastrointestinal tract, hemoptysis, painful swelling of the salivary and lacrimal glands, brain damage with symptoms of meningitis Meningitis - an inflammation of the meninges .

This disease affects mostly the blood vessels of small and medium caliber, they are destroyed walls immune complexes and thrombus formation, leading to impaired blood supply to tissues and organs.

The cause of the disease are genetic predisposition, susceptibility to allergies and infections, including chronic foci of infection in the body.

Symptoms

Behcet's disease is a chronic course with constant relapses and remissions of varying duration. Disease begins acutely, with a rash on the mucous membranes. But sometimes the triad can be incomplete: not affected all interested bodies.

First, the sores appear on the oral mucosa. This first appear aphthas with muddy contents, which after some time turn into bright red circular sores up to 10 mm in diameter, located on the gums, tongue, cheeks and lips mucous. Often these sores are merged together to form large ulcerated surface. Sores in the mouth are not prone to scarring and can pass on their own.

On the mucous membranes of the genitals is observed surface, sharply painful aphthous ulcers or deep process. First, on the mucosa appear single or multiple bubbles or blisters (bubbles with pus), which are then converted into aphthae. They have a diameter of 15 mm, a circular shape, yellowish bottom edge of the soft red and yellow color discharge. Ulcers begin with submucosal bumps that followed necrotic ulceration. After healing, the AFL and sores on the genitals remain scars.

Sometimes elements rashes appear on the skin in the form of various types of erythema, folliculitis with purulent content pustules under the nails, and so on. Erythema nodosum often occurs in women on the front of the leg, has a high morbidity, goes alone, leaving brown spots on the skin. Folliculitis often develops in men on the face, neck, back.

On the mucous membranes of eye disease can manifest as lesions of conjunctiva, cornea, ciliary body. In severe cases, the process can go on the optic nerve to the development of blindness or a significant decrease in visual acuity. It may also develop secondary glaucoma Glaucoma - a perspective possible blindness   (increased intraocular pressure).

The disease can be complicated by the defeat of the joints, usually the knee or ankle. Complications also arise in connection with the distribution at large vein vasculitis - retinal upper and lower vena cava. This leads to increased thrombosis and complications in the internal organs.

With long-term course of the disease can occur multiple lesions of the internal organs, including the central nervous system with the development of meningitis and blindness occur.

Diagnosis and treatment

Diagnosis is based on histological examination of tissue sections taken from the mucous membranes or skin rashes. On histological tissue sections clearly visible characteristic vascular changes. Immunological studies reveal the presence of vascular wall immune antigen-antibody complexes.

Treatment is carried out with the use of antihistamines, calcium supplements, antibiotics (the process is almost always associated infection) and glucocorticoid hormones.

Outwardly mouth washed with antiseptic solution (potassium permanganate, boric acid, extracts of calendula, St. John's wort). These same solutions and do sit-baths. They are used as an ointment to glucocorticoid hormones.

Behcet's disease - a serious illness that can occur for a long time, gradually capturing all the new organs and tissues. Therefore, it is important to see a doctor in time and spend a full treatment.

Galina Romanenko

Vagilak - it's not drugs, and dietary supplements, nonetheless, it promotes active rehabilitation of female genital mutilation as women of reproductive age, and girls and older women. But as a suppository is a drug is not released - feature is that it is specifically designed for oral use.

Why vagilak available in capsules for oral administration

In the pharmaceutical market there is a lot of medications for normalizing the microflora of the vagina, which are produced in the vaginal suppositories. But girls and young girls who are sexually active are not the introduction of vaginal suppositories Vaginal suppositories - for contraception and treatment of inflammation   contraindicated. However, this contingent of women also needs to restore the normal microflora of the genital tract, and sometimes even more than women of childbearing age.

The fact that girls and often young girls produced insufficient number of female sex hormones estrogen, which develops under the influence of the normal microflora of the female genital organs. The same situation occurs in the elderly, when the production of estrogen drops sharply. Since the normal microflora is not hormonal support, it begins to actively grow opportunistic and pathogenic microflora, whose representatives are always present in the mucosa of the genital tract of women. Contribute to this process many stresses that are present in the life of a modern woman, poor environmental conditions, eating disorders. All this contributes to the emergence of infectious and inflammatory diseases of female genital mutilation of girls and young women, which lead to violations of their reproductive (fertility) function.

Vagilak developed by pharmaceutical company Jadran (Croatia) for the prevention of infectious and inflammatory diseases in women, including girls, as well as to restore the normal balance of microflora in the genital tract after taking antibiotics, antivirals, immunomodulators, hormones and other drugs that violate the normal microflora in in the area.

Vagilak available in capsules which pass through the stomach and dissolve only in the intestine. Contained in capsules absorbed lactobacilli in the intestinal wall and through the blood rushing into the vaginal area, as it has an affinity to the art. Here they gradually (slow, it's not drugs, and dietary supplements) multiply and crowd out pathogenic microflora. Under the influence of vagilaka eliminated the symptoms of bacterial vaginosis Bacterial vaginosis - sex is not recommended   and greatly reduces the risk of recurrence of infectious and inflammatory diseases.

Diseases and conditions that can help vagilak

Indications for use vagilaka are:

• dysbiosis vagina Dysbacteriosis vagina - how to fight?   (bacterial vaginosis); vagilak thus can be used as a standalone tool or as part of an integrated treatment;
• During treatment with antibiotics, some anticancer drugs, corticosteroid, antifungal and antiviral drugs - they inhibit the development of normal microflora of the vagina The microflora of the vagina: purity ; vagilaka applied courses and after treatment with these drugs;
• subacute and chronic infectious and inflammatory gynecological diseases caused by non-specific infectious agents (eg, Escherichia coli or Staphylococcus);
• infections, sexually transmitted infections - in the complex treatment and after it to restore the normal microflora;
• preparing pregnant women for childbirth - rehabilitation of the genital tract for the prevention of postpartum septic complications;
• Preparations for diagnostic and therapeutic procedures, installation of intrauterine devices, as well as gynecological surgery, during which the female genital tract can be traumatized and microtrauma possible ingress of infection;
• Use of hormonal contraceptives and spermicides (agents that destroy sperm), which can disrupt the normal vaginal flora;
• inflammation of female genitals associated with insufficient secretion of female sex hormones estrogen (girls, young girls, women of childbearing age with hormonal disorders and in older women).

Dosage regimen vagilaka

Capsules vagilaka taken inside for the prevention of various disorders of the vaginal flora one capsule a day during meals with water. When applying vagilaka part of complex treatment of inflammatory processes with antibiotics it is applied on a capsule twice per day. This vagilak received between the use of antibiotics, so that between their reception was held for at least two hours.

Efficiency vagilaka depends on the duration of his admission: for the first signs of improvement it is necessary to take at least a month.

Galina Romanenko