Metronidazole Gel: effective in conjunction with other drugs - Application

November 17, 2011

  • Metronidazole Gel: effective in conjunction with other drugs
  • Application

Application

Metronidazole - an antibiotic, his trade names also include a meter, metrogil, Trichopolum Trichopolum - he treats?  Trichopolum - he treats?
 , Flags and others. Metronidazole by prescription, and is used to treat bacterial and parasitic infections of the respiratory tract, skin and stomach.

  • Bacterial infections

Metronidazole is used to treat infectious diseases caused by anaerobic bacteria, i.e. bacteria which are not vital for the required oxygen. These infectious diseases of the blood, bone, joints, central nervous system and heart.

  • Parasitic infections

Most often prescribe metronidazole for the treatment of trichomoniasis - infectious diseases, sexually transmitted diseases. Metronidazole is also used to treat giardiasis, amebiasis, and amebic liver abscess, and infections caused by anaerobic bacteria.

  • Airways

Metronidazole is also used to treat infections of the lower respiratory tract, such as pneumonia, lung abscess, and empyema. Empyema develops when the pleura, between the lung and the inner wall of the sternum, pus accumulates.

  • Gastrointestinal tract

Metronidazole is also used for the eradication of bacteria Heliocobacter pylori, which causes stomach ulcers and digestive system. In addition, metronidazole is administered for treatment of peritonitis and abdominal abscesses of the liver, as well as for the treatment of inflammation of the rectum caused by the bacteria Clostridium difficile.

  • Skin

Metronidazole in gel form is used to treat infections of the skin, including acne Acne: facial trouble  Acne: facial trouble
   and rosacea. Metronidazole vaginal gel is used to treat bacterial vaginosis How to get rid of bacterial vaginosis - the problem  How to get rid of bacterial vaginosis - the problem
 .

 Application | Metronidazole Gel: effective in conjunction with other drugs

How long does the side effects

Metronidazole - antibacterial drug used for the treatment of acne vulgaris and pink. Despite the high efficiency, metronidazole is not a universal remedy for all infections, and is not for everyone, as it has a number of serious side effects.

 Application | Metronidazole Gel: effective in conjunction with other drugs

How serious side effects

Adverse drug effects occur in approximately 34% of people taking metronidazole. Generally, the side effects appear after application of the second or third gel, and disappear when the body adapts to the drug.

 Application | Metronidazole Gel: effective in conjunction with other drugs

Types of side effects

The most common side effects of metronidazole: pharyngitis Pharyngitis - recommended home treatment  Pharyngitis - recommended home treatment
 , Sinus infection or upper respiratory tract, headaches, back pain and back pain, skin dryness and irritation, itching, burning sensation after application of metronidazole gel or cream.

 Application | Metronidazole Gel: effective in conjunction with other drugs

Features of the application of metronidazole

In combination with anticoagulants (eg, warfarin) Metronidazole increases the risk of uncontrolled bleeding during surgery or after trauma.

 Application | Metronidazole Gel: effective in conjunction with other drugs

Risks

Approximately 1% of patients administration of metronidazole results in formation of basal cell carcinomas, cancers of the skin.

 Application | Metronidazole Gel: effective in conjunction with other drugs

Cautions

Since information about the impact that has on the fetus metronidazole when used externally, no, doctors do not recommend the use of the drug for pregnant and lactating women. Because of the possible side effects of metronidazole is also contraindicated in persons who have had a blood dyscrasia (persistent abnormal changes of blood cell composition).


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Botulism - beware of canned food - Prevention and Treatment

June 21, 2009

  • Botulism - beware of canned
  • Prevention and Treatment

What is botulism and its causes

Botulism - a disease caused by a toxin (poison) of botulism bacteria. Botulism occurs by eating foods that contain the botulism toxin.

Botulinum bacteria are strict anaerobes, which means that they can exist only where there is no air. The place of permanent habitation of botulism spores is the soil from which they fall into the water, fruits and vegetables, groceries, and then in the intestines of humans and animals (mammals, invertebrates, birds, and fish)

These bacteria are widely distributed in nature and exist in two forms - the vegetative and spore. Vegetative form die at a temperature of 80 ° C for 30 minutes while refluxing - 5 minutes. Under unfavorable conditions, in an environment vegetative forms of pathogens botulinum produces spores that survive boiling for 5 hours and only killed by autoclaving (steam under pressure).

A feature of botulism is that of the vegetative forms with little warming can form their "dormant spores' ability to germinate only after six months. These spores are resistant to freezing, drying, and to direct UV radiation. In anaerobic or close to conditions (canned meat animals) dispute "come alive" and begin to produce toxins 375 000 times stronger than the venom of a rattlesnake.

Under normal environmental conditions the toxins stored up to one year, and in canned foods - for years. They are stable in an acidic environment is not destroyed by enzymes of the digestive tract, can withstand high concentrations (up to 18%) of salt, do not collapse in products containing a variety of spices. Toxins decompose relatively quickly under the influence of alkalis, when boiled completely lose their toxic properties for 15-20 minutes. The presence of botulinum toxin in foods does not change their taste properties.

 Prevention and Treatment | Botulism - beware of canned

How could I get botulism

Most often develop botulism by eating canned food (vegetables, meat, mushroom, fish), especially prepared in the home, as well as smoked and salted fish, ham, sausages, smoked meats. The greatest danger is posed by foods contaminated soil.

The toxin can enter the body not only through the digestive tract, but also via the airways by inhalation of dust. The patient botulism danger to others is not.

 Prevention and Treatment | Botulism - beware of canned

Signs

First signs of the disease can occur as early as 2 hours after infection (the incubation period, i.e. the time from infection to the first signs of the disease, from 2 hours to 10 days, more often - 12-24 hours). At the same time, shorter than the incubation period, the more severe the disease will occur.

First, there is a weakness, headache, dizziness Dizziness - if the ground is slipping from under his feet  Dizziness - if the ground is slipping from under his feet
 , Malaise, fever or a normal or slightly increased. Begin sharp cramping abdominal pain Abdominal pain: Types and Symptoms  Abdominal pain: Types and Symptoms
 , Nausea, vomiting, diarrhea. These events replaced the next day dry mouth, constipation and bloating. Somewhat later, visual disturbances appear: the patients see indistinctly (often marked ghosting objects) can not be read. There drooping eyelids, smoothing nasolabial folds and wrinkles due to paresis (partial paralysis) of the facial muscles. With the progression of the disease is disturbed swallowing, hoarseness appears, then the voice could entirely disappear. In severe cases, respiratory distress occurs, and the patient's death from suffocation or cardiac arrest.

 Prevention and Treatment | Botulism - beware of canned

Diagnostics

To confirm botulism conduct laboratory research vomit, feces and food residues (detection of botulinum bacteria), as well as the patient's blood (detection of toxin).

 Prevention and Treatment | Botulism - beware of canned

Treatment

Patients with botulism should be treated only in a hospital. First, patients must be conducted in such a gastric and intestinal lavage with 5% soda solution (neutralizes botulinum toxin), regardless of when it was infected.

The next step - the introduction protivobotulinicheskoy serum, antibiotics Antibiotics - whether they will help you in the foreseeable future?  Antibiotics - whether they will help you in the foreseeable future?
   and administering fluids intravenously reducing effect of the toxin (e.g., glucose). In severe forms of the disease is carried out by means of cleansing the blood and plasmapheresis hemosorption Plasmapheresis - cleansing the blood of toxins  Plasmapheresis - cleansing the blood of toxins
 As well as mechanical ventilation.

 Prevention and Treatment | Botulism - beware of canned

Prevention

The best prevention of botulism is eating only canned food industrial preparations. At home, you should observe the following rules:

  • Vegetables, fruits, berries and mushrooms should be well washed from the particles of the earth;
  • unacceptably long time taken to conserve, spoiled vegetables, fruits, berries and mushrooms;
  • fish after the catch you need to quickly gut, wash in running water and stored in a cold environment;
  • pickling mushrooms should not be made in hermetically sealed;
  • before eating canned foods are best boiled for 20-25 minutes (during which time splits botulinum toxin);
  • Before opening cans of canned food should be inspected - the development of the causative agent of botulism in them marked swelling of the bottom and lid cans (bombazh).

  Galina Romanenko






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