In accordance with the instructions the manufacturer's pentoxifylline during pregnancy should not be applied, since all necessary clinical studies when it is not tested. However, in practice, obstetricians often use this drug.

Why pentoxifylline is contraindicated in pregnancy

In accordance with the existing rules during pregnancy can only be used with the drugs through clinical trials established the safety and well-known ways of elimination. Pentoxifylline does not meet these requirements, as for the recognition of producers adequate and well-controlled clinical studies safety of pentoxifylline during pregnancy was conducted.

Why obstetricians still prescribe pentoxifylline

In the appointment of drugs such as pentoxifylline pregnant obstetrician takes into account the condition of the pregnant woman and the gestational age. During bookmark organs and tissues (in the first 12 weeks of pregnancy), no medication is best not to use - it can lead to developmental abnormalities.

But when it comes to an end tab fetal tissues from this woman's hard to say, so drugs that raise doubts about their safety, it is best to apply only after the twentieth week of pregnancy. And, of course, the purpose of such drugs require special control over condition of mother and fetus.

However, sometimes the condition of a pregnant woman is such that it requires the introduction of drugs that improve blood circulation, including pentoxifylline.

Under what conditions can a pregnant woman to be appointed as pentoxifylline

Pentoxifylline during pregnancy are usually appointed in violation of circulation in the mother - placenta - fetus. Such states are called twin-placental insufficiency (FPI). FPI is very dangerous to the fetus, as it may lead to changes in the development of individual organs, which are developing most actively in the period when impaired blood circulation. Particularly affected in this case, the central nervous system of the child, because the nerve cells can not exist in conditions of prolonged lack of oxygen.

FPI can be acute or chronic. Acute FPI occurs against a background of acute disorders of utero-placental blood flow, such as premature detachment of the placenta and cause miscarriage Miscarriage - can you protect yourself from it? .

Chronic FPN develops gradually as a result of violations of adaptation mechanisms and disorders of blood circulation in the placenta. Circulatory disorder leads to malnutrition placenta, leading to its gradual regression. In late pregnancy, a gradual decrease in blood flow in the placenta is physiological in nature: the body prepares for childbirth, so the blood vessels of the placenta gradually zapustevaet (it reduces the risk of bleeding during childbirth). This process is called aging of the placenta. But sometimes the placenta starts to grow old too early and it is dangerous to the fetus.

Chronic FPN may occur imperceptibly when the body cope with the violations and it does not require treatment. But in some cases, the body of a pregnant woman is unable to cope with disturbances, and it requires medical attention, as this condition causes chronic oxygen starvation of the fetus and could lead to his death. Pregnancy in these women often occurs on the background of the threat of interruption.

In addition, chronic FPN may cause intrauterine growth retardation Fetal development - week after week . Fruit is not it receives the necessary nutrients and oxygen, is lagging behind in weight and development. In contrast, just small babies, children with intrauterine growth retardation may suffer development of various organs, including the brain and spinal cord, immunity Immunity - types and characteristics in children in adults .

How does pentoxifylline during pregnancy

Pentoxifylline improves blood circulation by improving its flowability, and a small expansion of the small blood vessels. Improved blood flow is due to the fact that pentoxifylline prevents bonding (aggregation) of erythrocytes and platelets Platelets - what they are for the body? That reduces the viscosity of the blood. The less viscous the blood is easier to move through the blood vessels, especially since they are also slightly increasing.

Pentoxifylline has an effect on the body as a whole, in particular, causes an improvement in the blood flow and contributes to its better oxygenation in the lungs, which is very important for the fetus.

That is why, after weighing all the pros and cons, obstetricians is prescribed during pregnancy pentoxifylline. Himself pregnant women without a doctor's prescription, taking pentoxifylline (as, indeed, all other drugs) is strictly forbidden.

Galina Romanenko

Today, much attention is paid to the neuro-psychological state of pregnant women, as clearly shown that this condition has a significant impact on the course of pregnancy, including the mother and child.

The emotional state during pregnancy

Pregnancy is always reflected in the emotional state of the woman and, on the other hand, the emotional state of women has an impact on the course of pregnancy. This is especially noticeable in the beginning, in the first trimester of pregnancy, when a woman becomes emotionally vulnerable, often cries, there are sudden changes in mood, disturbed sleep. All this is the result of rapid changes in hormonal levels and in turn has a negative impact on the physical condition of the woman, compounding, for example, during early pregnancy toxemia. Too strong emotional outbursts can become even cause premature termination of pregnancy, as well as to a violation of family relationships, creating a vicious circle from which no woman will be able to get help postorenney with great difficulty.

If pregnancy occurs in a woman first, she may experience various fears: before the forthcoming birth for the child's health, fear that pregnancy would make her ugly and unattractive to the spouse, and so on. Fears of this kind are almost all women, but some of the most impressionable, they can go into depression, anxiety disorders and other mental disorders.

Starting from the second trimester of pregnancy, physical state, and along with it and the mood of the pregnant woman is usually stabilized, it blooms and begins to enjoy his new status. But during this period may be complications, such as toxicosis second half of pregnancy (gestational toxicosis) various irregularities in the fetal position and so on, which are also accompanied by emotional outbursts that does not contribute to pregnancy. Under the influence of stress How to beat stress? Create an oasis   in the second half of pregnancy there is a spasm of blood vessels, which increases the risk of gestosis and insufficient blood supply to the fetus. This leads to a miscarriage Miscarriage - why you lose the most precious thing?   or a lag in the development of the fetus.

Therefore, obstetricians are very closely monitoring the neuro-mental state of pregnant women recommend that they get as much positive emotions, more than a walk in the fresh air, especially at night Dreams: how to understand our dreams . If this does not help, then prescribe medication, as the emotional outbursts are dangerous not only for women but also for the child.

Why do I need Persen

In appointing the drug treatment for pregnant women must take into account the degree of risk exposure of a drug on the fetus. Therefore, preference is usually given to drugs of plant origin. One of the most effective and harmless herbal remedies with a calming effect is valerian root.

Besides soothing valerian root is able to normalize the activity of the autonomic nervous system (ANS), which innervate the internal organs and blood vessels. When emotional disorders is almost always a violation of work and ANS, which is manifested tachycardia, differences in blood pressure, nausea, vomiting and other disorders. Valerian copes with violations of this kind.

The disadvantage of valerian is that, in spite of its fame and popularity, she, like most herbal products are not fully understood. In addition, it can cause allergic reactions. But compared with other sedatives (e.g., chemical origin) valerian still safer.

Valerian is the main active ingredient of the drug of Persia. In addition, it includes mint Mint and its useful properties: aromatic freshness   peppermint and lemon balm - plant, which is also not contraindicated in pregnancy, however, their effects on pregnant women has also not fully understood. Both of these plants have a slight sedative and antispasmodic action and perfectly combined with the main active ingredient - valerian.

If there is a question that the emotional state of the woman is such that could harm pregnancy and fetal status and it requires the appointment of medical treatment, the drug of choice is often the Persians.

Persen not formally contraindicated in pregnancy, however, given that the necessary clinical studies on its effect on pregnant women have not been conducted, it is prescribed in the case where the expected benefit from taking it to the mother's body than the potential harm to the fetus.

Assigns persen pregnant doctor.

Galina Romanenko