Mastocytosis - a rare disease caused by the accumulation in the body tissues of a large number of mast cells. These cells in large quantities released into the blood histamine and other chemicals, causing symptoms such as skin rash, itching, and hot flashes. Mast cells are a type of cells that are found in certain parts of the body - for example, in the skin, also the inner shells lung and stomach. They play an important role in the immune system.

Types of mastocytosis

There are two basic types of mastocytosis:

• Cutaneous mastocytosis, caused by excessive numbers of mast cells in the skin;
• Systemic mastocytosis, which is caused by an excess of mast cells in other tissues.
• Cutaneous mastocytosis occurs much more often than systemic mastocytosis.

Because of excess fat cells have the potential to cause the release of a large amount of histamine in people with both mastocytosis both types there is an increased risk of a severe allergic reaction - anaphylaxis. This condition is very rare, but can lead to the death of a person in just a few minutes. People diagnosed with mastocytosis, may be recommended to carry everything needed for the injection of adrenaline that can be used if necessary to prevent the worsening of the symptoms of anaphylactic shock.

Symptoms

• Cutaneous mastocytosis

The main symptom of cutaneous mastocytosis are different skin lesions - nodules, seals (both flat and convex), blisters filled with fluid, slightly protruding large patches on the skin, which is the structure of the touch and appearance differs from that of healthy skin.

Usually these symptoms appear on the body. The number of nodules and blisters on the skin can be very different. In some cases, there is only one seal or stain; sometimes, it is more than 1,000.

• Systemic mastocytosis

If systemic mastocytosis observed flare-ups of symptoms lasting about 15-30 minutes. The most common signs of such attacks are:

• Hot flashes;
• Palpitations (irregular heartbeat);
• Dizziness.
• Less commonly, the following symptoms:
• Headache;
• Shortness of breath;
• Chest pain;
• Nausea;
• Diarrhea.

Some people during an attack may experience a sudden drop in blood pressure Blood pressure - dangerous if his swing? . Low pressure can be associated symptoms such as dizziness Dizziness - if the ground is slipping from under his feet , Fainting, blurred vision, confusion, weakness.

After the attack people within a few hours feeling of sluggishness and lethargy.

These attacks occur when fat cells are released into the blood suddenly a large amount of histamine; this usually occurs as a result of exposure to certain triggers. These triggers may include:

• Physical factors such as heat, cold, fatigue and intensive exercise;
• Emotional factors such as stress How to beat stress? Create an oasis   and excitement;
• Some foods, such as cheese, clams and spices;
• Insect bites;
• Infections, such as cold or flu;
• Alcohol consumption;
• Taking certain medicines, such as ibuprofen, aspirin and antibiotics.

Abnormal mast cells in the bone marrow and can cause symptoms such as:

• Pain in the stomach caused by peptic ulcer;
• Lack of appetite;
• Weight loss;
• Inflammation of the liver, which in turn can cause jaundice (yellowing of the skin and whites of the eyes) and cause lethargy;
• Enlargement of the spleen, which can cause severe pain in the abdomen;
• Joint pain;
• Inflammation of the lymph nodes;
• Weakness;
• Fatigue;
• Changes in mental status - confusion, irritability unfounded Irritability - you try to control my temper , Decreased concentration and memory disorders.

Baziron speaker is only available in the form of a gel with different concentrations. But some people are confused ointments and gels, and mistakenly called baziron ointment. Nevertheless, ointment - a different dosage form which is different from the gel. Baziron comes in gel form and then, in order to better to dry oily skin.

The ointment is different from the gel

Ointments and gels are undosed soft dosage forms. Ointments are homogeneous, with no grains, soft to the touch weight. The ointments include drugs and ointment base (vegetable and animal fats, fat-like substances, oil products, synthetic substances). Ointments are easily absorbed into the skin and mucous membranes.

Gel - a dosage form is a soft viscous consistency. The composition of the gel also has a drug and the foundation. Gels prepared by forming a slurry of the polymer powder (acid) in water and adding a small amount of neutralizing agent (base). Then the mixture is stirred, and when it thickens, then forms a viscous gel. The gel can retain its shape, it has elasticity and plasticity.

Compared to the ointments, gels are more physiological form, since they have acidity, acidity close to the skin, do not clog the pores of the skin, quickly and evenly distributed. Gels can have as dried (e.g., baziron) and, on the contrary, the liquid saturating the skin (hydrophilic) properties.

Gel baziron - modern medicine for the treatment of acne

Gel baziron produced three kinds of 2, 5%, 5%, 10% concentration. Different concentrations allow its use for different skin types and different degrees of acne Acne: facial trouble Without disrupting the rest of the skin condition.

When applied to the skin gel baziron it enters the pores and dissolve comedones (a mixture of desquamated cells sebum) - the so-called keratolytic action. It then penetrates into the sebaceous gland and reduces the intensity of their operation, that is reduces the amount of sebum excreted. Simultaneously, also in the field since it inhibits the proliferation of pathogens. And finally - it improves oxygen supply of the skin cells.

All these properties allow Baziron is slowly but surely changing the metabolic processes in the skin. Restoring all metabolic processes take a long time, so the first time the result of the treatment can be seen only after a month. And three months is much cleansed skin, lose the characteristic shine and will acquire a natural pink hue.

How to apply the gel baziron

The proper application Baziron depends on the result of treatment, so daily (1 - 3 times a day, as the doctor may) need to perform the following procedure:

• before applying Baziron need to cleanse the skin to remove make-up and sebum; Do not clean your skin dries means (eg, alcohol-based lotion), better to just wash with water at room temperature with a facial wash or with a special soap that does not dry the skin;
• gently blot the skin with a soft towel and rub alcohol-free lotion;
• dot applied to the skin gel baziron (you can not, so he got into the eyes, mouth and lips) on pimples and blackheads; Accidental Baziron in the conjunctiva, the mucous membrane of the mouth or mouth rinse them under running water; If we treat venous ulcers of the lower extremities, the gel is applied only on the edges of ulcer; gel is quickly absorbed into the skin and begins to act.

The concentration of the gel baziron and the multiplicity of its application to the skin sometimes have to choose, for example, if its application appeared too severe dryness, then perhaps more appropriate gel concentration or less is to reduce the number of procedures.

The course of treatment Baziron at least three months - only in this case, you can expect consistent effect. But after a full course are worsening. If there is a need for a repeated course, this is done only on prescription.

Who should not use Baziron

Baziron not be used during pregnancy, infant feeding Breastfeeding - a personal choice   chest and for children under 12 years. These categories of patients can not be treated baziron because it is somewhat absorbed into the blood, from which water can get into the human milk, thus exerting adverse effects on the fetus or child.

You can not be treated Baziron are hypersensitive to its components, or if you are allergic to them. If baziron causes severe irritation of the skin (dryness, swelling Prevention and treatment of edema - it is important to understand the root cause Redness), you should consult with your doctor to decide whether or not to continue treatment.

Baziron - a gel, ointment and instead given dosage form more suitable for the treatment of acne Acne treatment: how to get rid of blackheads .

Galina Romanenko