- Veroshpiron - used with caution!
- Side effects
- In gynecology
- Questions and answers
Veroshpiron it is known for a long time and has proven itself to the best advantage. However, this drug should be taken strictly on prescription, since in addition to removal of the liquid, he still contributes to the delay in the body of potassium, without which it can not function properly the heart muscle. But too much potassium to the body is dangerous.
To write it out?
Veroshpiron used to treat high blood pressure and fluid retention, due to which the developing heart disease, kidney and lung problems. Veroshpiron stimulates kidney so as to remove excess liquid and salts with urine.
How to take it?
It is usually recommended to take veroshpiron twice a day. Follow the instructions received from the doctor or the directions on the package. If you need to take veroshpiron times a day, it is better to do it in the morning; If twice a day, morning and afternoon. Do not take it in the evening, at night, otherwise you will have too often go to the toilet.
Veroshpiron produced in the form of tablets and capsules. Take it with food or immediately after meals. The doctor can alter the dosage and frequency of reception depending on how your body will respond to the drug.
During the reception veroshpirona weigh yourself every day or every other day and immediately contact your doctor if you start to gain weight quickly.
Be sure to pass all the examinations, your doctor orders. It is necessary to regularly check blood pressure, as well as to donate blood for analysis. Do not stop taking veroshpirona without consulting your doctor.
It should make some changes in the diet. Avoid salty foods, salt substitutes containing potassium and a large number of products, which include a substance (this, for example, bananas
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, Apricots, coconuts, dates, prunes, peaches
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, Grapefruit, tomatoes and oranges).
If you forget to take veroshpiron while, take a tablet as soon as you remember about it. However, if the time to take another pill just around the corner, take the missed dose should not be veroshpirona.
Be sure to tell your doctor if you have kidney disease before you start taking veroshpirona.
Aspirin can weaken the effect of veroshpirona and some other medicines lower blood pressure too, which leads to dizziness and fainting.
Tell your doctor about any medications, prescription and non-prescription, you are taking. This also applies to vitamin supplements, especially those containing potassium.
Keep the medicine out of the reach of children, dry and dark place at a temperature not higher than 25C.
The mechanism of action veroshpirona
Veroshpiron (international non-proprietary name - spironolactone) - diuretic drug, which unlike conventional diuretics potassium does not output, and contributes to its accumulation in the body.
The mechanism of action veroshpirona based on the fact that it competes with adrenal hormone aldosterone-binding to its receptors (the nerve endings that are sensitive to aldosterone) whereby excreted liquid exhaustion, sodium and chloride, and potassium and urea remain in the body and can accumulate . In addition, reduced urine acidity.
Effect after administration veroshpirona appears on the second to fifth day after the start of reception.
When administered drug is completely absorbed into the blood, binds to blood proteins, then enters the liver, it is decomposed into individual metabolic products (metabolites) and excreted in the urine and feces.
Indications and contraindications for use veroshpirona
- at a consistently high blood pressure along with other drugs;
- edema with chronic cardiovascular disease;
- at elevated levels in the blood of the adrenal cortex hormone aldosterone (eg, edema of renal origin, cirrhosis of the liver, which is accompanied by accumulation of fluid in the abdomen);
- with a deficiency in the body of potassium and magnesium, combined with indications for receiving diuretics;
- to identify primary hyperaldosteronism (increased aldosterone release of adrenal hormones).
Contraindications for use veroshpirona:
- at Addison's disease (insufficiency of the adrenal cortex);
- with high content of potassium in the blood;
- under reduced sodium content in the blood;
- with severe renal impairment;
- at a delay of excretion of urine;
- malabsorption of simple sugars (sucrose, glucose
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- Pregnancy and breast-feeding
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- Children under 3 years of age;
- if you are hypersensitive to the components of the drug.
With care, individually adjusted doses veroshpiron appointed in violation of liver and kidney function, some cardiovascular diseases, diabetes and old age. During treatment veroshpironom can not drink alcohol. At the beginning of treatment veroshpironom can not drive vehicles and engage in other activities that require attention, the period is set individually.