Jodomarin - a drug. which is very well tolerated and has almost no contraindications. It can be administered in any age, even in the neonatal period. However, and this drug has side-effects and contraindications.

Features jodomarin action on the human body

Jodomarin Kosovo has the composition active substance - potassium iodide. If ingestion it is absorbed into the blood, it enters the thyroid gland and decomposed to iodine ions.

Thyroid hormones affect the entire body. But above all, they stimulate the metabolism Improves metabolism and losing weight without dieting   - The exchange of proteins, fats, carbohydrates. Increases the energy balance of the body, it stimulates the cardiovascular and nervous systems. In addition, thyroid hormones affect all other endocrine glands.

With an excess of thyroid hormones Thyroid hormones: mechanism of action and physiological effects   heart attacks occur. Increased blood pressure, shaking hands, comes excitement and insomnia. With a lack of these hormones appear lethargy, drowsiness, lethargy, dry skin and a gradual decrease in intelligence to full dementia. Iodine deficiency can also lead to the development of endemic goiter - thyroid tissue overgrowth, which can not cope with its function and razarstaetsya under the influence of pituitary hormones.

Jodomarin mainly used prophylactically in areas where there is a lack of iodine in the environment and to prevent a recurrence of the disease after treatment. If goiter develops with normal thyroid function, then children, adolescents and adults up to 40 years jodomarin can be applied as a treatment.

What side effects may occur when taking jodomarin

Jodomarin - a quality and safe drug, in small doses, which are assigned as a prophylactic measure, it has no side effects.

Side effects appear in the application of therapeutic doses jodomarin - 150-300 g and more. These doses should not be taken without prior examination, as they are able to translate latent hyperthyroidism (high thyroid hormone in the blood) in hyperthyroidism - with the appearance of the characteristic symptoms of this condition and complications. Especially dangerous are such states for the elderly, as often give complications of the cardiovascular system.

Acute intoxication may develop on the background of an overdose jodomarin. This condition is dangerous. It appears brown mucous membranes, vomiting, abdominal pain Abdominal pain: Types and Symptoms , Bloody diarrhea, dehydration. If assistance is not provided in a timely manner, the shock may occur. First aid in such cases is a gastric lavage with water to dilute it with starch. Irrigate need up until the starch turns blue - a sign of the presence of iodine in the vomit.

Allergic reactions may occur jodomarin different types of rash and angioedema.

Contraindications

Contraindications for use jodomarin quite a bit. First of all, this increased blood levels of thyroid hormones - hyperthyroidism. Do not use jodomarin at high doses (300 micrograms per day) are also in the toxic thyroid adenoma Thyroid adenoma - a benign tumor   - Benign tumors producing hormones, as well as in nodular goiter.

Contraindications jodomarin is herpetiformis (senile) Duhring dermatitis - a skin disease in which the patient appears intolerant of potassium iodide, which is the active substance jodomarin. Do not use if you are hypersensitive jodomarin sick of this drug.

Do not take jodomarin drugs for the treatment of radioactive iodine and thyroid cancer or suspected it.

Jodomarin - a drug, which has few side effects, and contraindications for use, however, they must be taken into account when administered, especially in therapeutic doses.

Galina Romanenko

  Graves' disease - a violation of the immune system, which can lead to excessive production of thyroid hormone (hyperthyroidism). Although hyperthyroidism can cause many diseases, Graves' disease is the most common cause of it.

Since thyroid hormones affect the operation of the various systems of the body, from Graves' disease may be very different symptoms; it often has a negative impact on the overall health of the patient.

Graves' disease is rarely life-threatening. It can develop in anyone, but is most common in women under 40 years. The main goal of treatment in this state - to inhibit the production of thyroid hormones Thyroid hormones: mechanism of action and physiological effects   and reduce the symptoms.

Symptoms

The most common symptoms of Basedow's disease are:

• Increased anxiety
• Irritability
• Sleep disorders
• Weakness
• Palpitations and / or irregular heartbeat
• Fine tremor of the hands and fingers
• Sweating or unusually warm and moist skin
• Increased sensitivity to heat
• Weight loss despite a normal feeding behavior
• The increase in the thyroid gland (goiter)
• Changes in the menstrual cycle
• Erectile dysfunction or loss of libido
• More frequent than usual urge to defecate, and diarrhea
• Protruding eyes (Graves' ophthalmopathy)
• Thick, red skin on the legs and upper sides of the foot (thyroid dermopathy)

Graves ophthalmopathy

Approximately half of the patients with Graves 'disease there are certain signs of disturbances, called Graves' ophthalmopathy. This violation of inflammation and other changes related to the work of the immune system, affecting muscle and other tissues around the eyes. This leads to symptoms such as:

• Protruding eyes
• Excessive tearing
• Dryness and irritation of the eyes
• Swollen eyelids
• The feeling of pressure or pain in the eyes
• Redness and inflammation of the eyes
• Increased sensitivity to light
• Ghosting visible objects
• Limited mobility of the eye, causing sight becomes frozen
• Blurred and / or blurred vision (uncommon)
• Ulcers on the cornea (rare)

When you see any symptoms of Graves' disease should consult a doctor. So you can prevent many of the complications associated with this disorder.

Causes

The cause of goitre is a dysfunction of the immune system. Normally, the immune system produces antibodies to protect the body against viruses, bacteria and other foreign substances. In Graves' disease, for reasons that are not entirely clear, the immune system produces antibodies to the protein, which is on the surface of thyroid cells.

In a healthy body the thyroid gland regulate the hormones that the pituitary gland produces. The antibodies that cause hyperthyroidism - receptor antibodies thyroid stimulating hormone (TSH) imitate the hormones produced by the pituitary gland. Thus, antibodies to receptor TTG disrupt the normal regulation of the thyroid gland, resulting in excessive production of thyroid hormones, or hyperthyroidism Hyperthyroidism: increased secretion of thyroid hormone .

Thyroid hormones regulate metabolism Improves metabolism and losing weight without dieting , Heart and nervous system, body temperature, muscle strength, the menstrual cycle. Graves' disease may thus in some degree affect all these functions, significantly changing the quality of life of the patient.

Graves ophthalmopathy develops presumably due to the fact that the activity of anti-TSH receptor causes inflammation of the tissues surrounding the eyes.

Risk factors

• Family history. It is assumed that there are genes, through which susceptibility to Basedow's disease is inherited. If the violation has been, or have your relatives, you are at risk.
• Paul. The likelihood of developing goitre among women is significantly higher than that of men.
• Age. The most common Graves' disease develops before the age of 40 years.
• Other autoimmune disorders, such as diabetes or the first type of rheumatoid arthritis Arthritis - a variety of forms and complications Increase the risk of Graves' disease.
• Emotional and / or physical stress can be a trigger for Graves' disease, especially in people with a genetic predisposition to it.
• Pregnancy. During pregnancy and soon after delivery likelihood of developing this disorder is particularly high.
• Smoking also increases the risk of Basedow's disease, since it weakens the immune system. The risk becomes higher, the more the patient smokes.