- Buserelin - helps cancer
- As produced by the female sex hormones
Buserelin - a substance that belongs to the GnRH analogues. It acts on the pituitary gland - the gland that produces and stores, many hormones, including sex hormones, luteinizing hormone (LH) and follicle stimulating hormone (FSH). In females, LH and FSH stimulate the production of estrogen by the ovaries, thus helping to regulate the menstrual cycle.
The volume released into the blood LH and FSH controls another hormone - gonadotropin-releasing hormone (GnRH) or GnRH. GnRH acts on specific receptors in the pituitary gland, stimulating the release of LH and FSH and the subsequent production of estrogen.
Buserelin is a synthetic form of GnRH. It acts on the GnRH receptors as well as the natural hormone.
At the beginning of its use buserelin causes increased production of FSH and LH and estrogen
Estrogen - the key to bone health
. However, with prolonged use, making it less sensitive to the pituitary GnRH whereby ejected less FSH and LH and estrogen production is being phased out. This effect buserelin used to treat endometriosis.
Endometriosis - a disorder in which tissue structurally similar to the endometrium of the uterus begins to grow out. Because it stimulates the growth of estrogen, reducing the hormone using buserelin it helps stop the growth of tissue and relieve symptoms. For the treatment of endometriosis usually administered buserelin reception in form of a nasal spray. The recommended duration of treatment - six months; Therapy should not last longer or be repeated after some time.
Buserelin is also used to treat infertility
Infertility Treatment - What principles are priority
. If infertility in women is caused by problems with the natural ovulation
Ovulation - How to determine as accurately as possible?
First she had stopped the production of FSH and LH using buserelin. In the next phase it is administered synthetic FSH, LH and gonadotropins to artificially stimulate ovulation.
Attention!
Buserelin can cause side effects such as dizziness and blurred visible objects, so the ability to control the vehicle during its reception is disrupted.
Before the treatment of endometriosis using buserelin woman should stop taking hormonal contraceptives and use of hormonal contraceptives. (Although buserelin and stops ovulation, if the treatment is interrupted even for a few days, ovulation may occur).
Usually within the first few weeks of treatment with buserelin women begin menstruating. After that, during the entire course of treatment may experience vaginal bleeding.
Tell your doctor about any medications you are taking before you start receiving buserelin.
Buserelin may reduce the effectiveness of anti-diabetic drugs. During the course of treatment may be necessary to take them in increased doses.
Buserelin should be used with caution in the following cases:
- Depression
- Diabetes
- Elevated blood pressure
- Metabolic bone diseases such as osteoporosis
Contraindications
Buserelin should not be taken for children and, in most cases, young people; pregnant and lactating women. In addition, this drug is contraindicated after menopause, vaginal bleeding of unknown origin and hormone-cancer. Buserelin also not be taken if you are allergic to the components of the drug.
Side effects
- Irritation of the nasal mucosa, epistaxis, impaired ability to sense smells and tastes (only if you use a nasal spray)
- Hot flashes
- Increased perspiration
- Vaginal dryness
- Decreased libido
- Reduction of bone density
- Changing the size of the breast
- Lamination polish
- Dryness of the skin and eyes
- Stagnation of fluids in the body that causes swelling of the face, hands and feet
- Signs of digestive disorders such as diarrhea, constipation, nausea, vomiting or abdominal pain
Abdominal pain: Types and Symptoms
- Isolation of the milk from the nipple
- Dizziness
- Heart palpitations
- Anxiety and nervousness
- Headache
- Sleep disorders
- Causeless tiredness
- Changes in appetite and / or weight