One of the consequences of adenomyosis
Adenomyosis - the consequences largely depend on the woman
Infertility is a woman. Moreover, the heavier the disease, the longer it exists, the less chance of conceiving. However, not all that bad, quite often use assisted reproductive technologies, such as IVF and when adenomyosis. But in this case, the chances of getting pregnant are very small. Therefore, every woman who wants to carry and give birth to a child should begin treatment as soon as she was diagnosed with adenomyosis.
The effectiveness of IVF with internal endometriosis reaches 35-60% of cases. Therefore adenomyosis - it is not a sentence, but rather a need that requires action.
What is adenomyosis
Adenomyosis (internal endometriosis) - a disease that affects the uterine wall (muscular and serous membrane). Thus endometrial cells grow deeper strata uterus, forming passages. As a rule, adenomyosis occurs after abortion and childbirth, occurs with inflammation of the uterus, stress and constant insolation (the love of solariums). Also, adenomyosis can be hereditary. Manifested internal endometriosis heavy and prolonged menstrual periods, "daubs" before and after menstruation, pain and infertility. In addition, adenomyosis is always accompanied by adhesive process, which is an additional factor infertility.
Adenomyosis on ultrasound
An additional and quite reliable diagnostic method is a survey at adenomyosis ultrasound. On ultrasound detected the cellular structure of the myometrium (in diffuse form), in which there are point or melkokistoznye education. The boundary of the mucous membrane and muscular layer of the uterus has a sinuous rather than smooth in nature, with the thickness of the uterine wall over the back of the front. In the case of nodular form of adenomyosis on ultrasound in addition to the cellular structure of the myometrium visualized nodes heterogeneous nature, around which there is no capsule.
Indications for IVF when adenomyosis
In vitro fertilization with the adenomyosis is carried out in the following cases:
- Lack of effect of treatment
After the hormonal and / or surgical treatment and the absence of pregnancy within one to two years it is recommended to resort to IVF.
Adhesions in the pelvic area captures the bowel, bladder, ovaries and fallopian tubes (which leads to obstruction).
Anovulation often accompanies adenomyosis, which is a consequence of the violation of production of female sex hormones and increased prolactin.
When adenomyosis
Adenomyosis - avoid constant stress
is impossible as a result of implantation of "perversions" of immune responses. In addition, impaired immune response leads to sperm uptake by macrophages.
Preparation and particularly IVF with adenomyosis
Prior to in vitro fertilization in the presence of adenomyosis is necessary to pre-surgical and hormonal treatment. Surgical treatment is laparoscopic removal of endometriosis (eg, nodes in the nodular form of adenomyosis) and dissection of adhesions (Restoring egg from the ovary to the tube and tubal patency). Then hormone therapy is appointed.
The goal of hormonal treatment - a temporary suppression of estrogen. For this purpose, analogues of gonadotropin-releasing hormone (eg Buserilin, Dekapetil). The optimal use of the deposited preparations; Depot creates a constant concentration of the hormone contained in the preparation for a long time, which is necessary for the disappearance of endometriotic heterotopias. In the appointment of hormonal therapy using "long" and "extra-long" scheme.
"Long" stimulation protocol involves administering agonists with a 21-day menstrual cycle
The days of the menstrual cycle: Four phases
. For example, the appointed Diferelin daily injections (at 0, 1 mg) or a single administration Diferelin depot (3, 75 mg). Then spend the stimulation of ovulation from the third to fifth day of the menstrual cycle.
In "Ultra Long" protocol administering releasing hormone agonists conducted during several months (two to six) and then stimulate ovulation
Ovulation - How to determine as accurately as possible?
.
Anna Sozinova
Article Tags:
- adenomyosis and pregnancy