Endometrial hyperplasia, adenomyosis - are diseases which are based on the excess in the body of female hormones estrogen. And in fact, in both cases under the action of estrogen occurs overgrowth of the mucous membrane of the uterus (the endometrium).
Why develop hormonal diseases such as endometrial hyperplasia and adenomyosis
Endometrial hyperplasia of the uterus is called overgrowth (proliferation) of the inner lining of the uterus (endometrium) in the first half of the menstrual cycle under the influence of excess female hormone estrogen.
Typically, this condition is noted, either absolute or relative lack of another female sex hormone - progesterone, which supports the second half of the menstrual cycle, estrogen and inhibits the secretion of growth of the endometrium.
Lack of progesterone and estrogen excess leads to long-term proliferation of the endometrium. When hormonal support stops a thick layer of epithelium is rejected, accompanied by heavy bleeding. Sometimes estrogen allocated waves for a long time, which leads to not so abundant, but prolonged bleeding.
Contributing factors contributing to the development of endometrial hyperplasia, are serious emotional and informational load, stress, traumatic brain injury, brain disease, endocrine disorders (eg, obesity, diabetes), chronic inflammation of the female genital organs, tumors (eg, uterine fibroids ), polycystic ovary syndrome, heavy births, induced abortions, and so on.
Adenomyosis - is a form of endometriosis characterized by the growth of endometrial tissue in the muscle layer of the uterus (myometrium). One reason is adenomyosis growth (proliferation) endometrial exposed too much estrogen. But for the development of endometriosis requires additional conditions: decreased immunity (normal immune cells destroy the cells of the endometrium, trapped in other tissues), violation of the permeability of the basal (not rejected during menstruation, which is then recovered the rest of the endometrium - functional) layer of the endometrium. Violations of the permeability of the basal layer of the endometrium may have a genetic or congenital in nature and can occur under the influence of high pressure in the uterus for violations of the outflow of menstrual blood.
The main symptoms of endometrial hyperplasia and endometriosis
The main symptom of endometrial hyperplasia is a lengthening of the menstrual cycle in combination with strong menstrual bleeding (menorrhagia). Sometimes the bleeding is not overly abundant, but long - this suggests that estrogens are allocated relatively long in small portions. Characteristic and acyclic bleeding - metrorrhagia.
Regular significant blood loss leading to iron-deficiency anemia. The symptoms of this deficiency anemia are fatigue, weakness, fatigue, decreased performance, pale skin and mucous membranes, headaches, dizziness, and sometimes - fainting.
Endometrial hyperplasia is often accompanied by infertility or miscarriage
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. Women with endometrial hyperplasia identified and other endocrine diseases - obesity, diabetes
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, Thyroid disease
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, The adrenal glands. pituitary and so on. In these diseases are the hallmarks of high blood pressure and disorders of the liver.
The characteristic symptoms of adenomyosis
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are menstrual and intermenstrual bleeding, iron deficiency anemia and severe pain in the abdomen, which begin a few days before menstruation and end a few days after they started.
Suspicion of these hormone-dependent disease already appears on the basis of complaints of the sick woman and her gynecologist examination. After that, the study taking swabs from the vagina, cervix and urethra, blood on hormones, ultrasound is performed, if necessary - the diagnostic hysteroscopy, x-ray, magnetic resonance imaging. To identify possible pockets of extragenital endometriosis conducted a full examination of all internal organs.
Treatment of endometrial hyperplasia and adenomyosis is conducted only after a complete examination and final diagnosis. Typically, this is a long process that requires careful execution of a woman doctor's appointments.