Orgametril - a synthetic analogue of the natural hormone progesterone the female sex. Since endometriosis in the body produces a lot of estrogen and progesterone little appoint orgametril, which inhibits the synthesis of estrogen and helps to normalize hormonal levels.
What causes endometriosis
The main cause of endometriosis is a hormonal background, in which the body produces a lot of female sex hormones of the first half of the menstrual cycle (estrogen), which contribute to the widening (proliferation) of the mucous membrane of the uterus - the endometrium. Normally, in the second half of the menstrual cycle to replace the estrogen, progesterone comes
Progesterone - norm and pathology
Which inhibits the proliferation of the endometrium and in the process takes the stage secretion.
When violations of hormonal progesterone little, so long endometrium grows under the influence of estrogen, and when they become a little rejected, accompanied by prolonged heavy bleeding. Rejects endometrium may enter the muscle layer of the uterus and other organs and tissues and form there endometriosis, which usually tend to increase during the cyclic change.
How does endometriosis orgametril
Orgametril (active substance - lynestrenol) is a synthetic analogue of progesterone, which is available in tablets for oral administration, the pharmaceutical company Organon (the Netherlands). Each tablet contains 5 mg orgametrila active principle.
Part of the orgametrila lynestrenol has an effect similar to natural progesterone.
It inhibits the proliferation of the endometrium, causing it to secrete - allocate secret that prepares the uterine wall for the introduction of a fertilized egg. This prevents excessive endometrial growth, and therefore the subsequent strong bleeding.
Receiving additional progesterone leads to suppression of estrogen formation, that is to normalize the menstrual cycle. This helps to suppress the dissemination of endometriosis.
In what cases and how endometriosis appointed orgametril
Orgametril assigned when not heavy and not too common forms of endometriosis. Inhibition of estrogen synthesis and proliferation of the endometrium results in such a case good results - Prevention of growth of endometriosis and sometimes to their regression.
However, in severe forms of endometriosis, this drug is not suitable - in such cases today administered hormones completely suppress ovarian function, thereby terminate cyclic changes in the uterus.
Orgametril take only prescribed by a doctor after survey. The usual course of the drug - one tablet a day at the same time from 14 th to 25 th day of the menstrual cycle
The days of the menstrual cycle: Four phases
. If endometriosis is accompanied by strong menstrual bleeding, orgametril administered two tablets once a day daily for 10 days.
What side effects may occur during treatment
Orgametril may cause some side effects: uterine bleeding or spotting in the middle of the menstrual cycle (after a while it goes), libido disorders, nausea, abdominal pain
Abdominal pain: Types and Symptoms
Increase in body weight.
Less common side effects such as headache, dizziness, irritability or depression, sweating, acne, hair growth on male type, the appearance of the face of brown age spots, itchy rash on the skin, icteric staining of the skin and sclera, cessation of menstruation, pain breast area, swelling, older women may cause thirst and frequent urination.
Contraindications for use
Orgametril has a lot of contraindications:
- individual intolerance of components;
- pregnancy and lactation;
- severe liver disease;
- uterine bleeding of unknown nature;
- diseases that are exacerbated during pregnancy or when taking hormonal medications (cold sore, jaundice, skin rash, hearing, etc.);
- the tendency to thrombosis;
- severe mental illness
Mental illness - ashamed to ask for help?
Which are accompanied with depression;
- congenital disorders of lipid metabolism.
Precautions orgametril prescribed for high blood pressure.
Orgametril copes well with some forms of endometriosis, but it can be taken only as directed and supervised by a doctor. Endometriosis generally can not be treated independently.
- treatment of endometriosis