Candles Polizhinaks would be more correct to call vaginal capsules - in such a dosage form of the drug is available for topical application of the French pharmaceutical company Laboratory Innotech Internacional. Polygynax vaginal capsules are easy to use and is particularly effective when mixed gynecological infections.

Features of infectious and inflammatory diseases of the external genitalia of women

Infectious-inflammatory diseases of vulvar caused by non-specific infection usually develop at lower immunity. Immunosuppression contributes to the fact that these infections often are mixed, that is caused by bacterial and fungal microflora.

Such nonspecific infection called because all it pathogens cause inflammation, similar in its manifestations as opposed to specific infections (eg, gonorrhea Gonorrhea - self-ruled   It has its own distinctive features). For non-specific infections are processes caused by staphylococcus, streptococcus, E. coli, Proteus, and so on.

The inflammatory process is often called first bacterial microflora, and then, during the treatment antimicrobials joins fungal infection (usually the yeast genus Candida). Therefore, many medicinal preparations for topical use are composed, as antimicrobial and antifungal agents.

How do vaginal capsules Polizhinaks

Polizhinaks a combined preparation for topical use, which is composed of three antibiotics. Two of them (neomycin and polymyxin B) suppress the vital activity of the bacterial flora, and one (Nystatin) is an antibiotic with antifungal activity. Thus Polygynax antibacterial and antifungal activity.

Neomycin and polymyxin B - two antibiotics that complement each other and suppress the livelihoods of almost all bacterial flora, caused by an infectious-inflammatory gynecological diseases. Nystatin copes with fungi genus Candida.

However, given that the flora quickly get used to the different drugs and loses sensitivity to them, any antibacterial and antifungal agents, including Polizhinaks, appointed only after the laboratory and the establishment of the sensitivity of pathogens to these drugs.

Excipients gel capsules is dimethyl polysiloxane, which surrounds the vaginal wall, evenly distributing them active ingredients and taking the itching. At the same time it improves the power of the vaginal walls.

Who and how appointed

Polizhinaks indicated for the local treatment of vaginitis (inflammation of the external genitalia and vagina) and cervicitis (inflammation of the cervical canal) caused by non-specific bacterial or fungal infection.

Furthermore, Polygynax widely used for prevention of complications after various gynecological surgery, therapeutic and diagnostic procedures. So, it is applied to a variety of gynecological operations, including those to abortion, birth, introduction of intrauterine devices, hysteroscopy Hysteroscopy - examination of the uterus inside   (therapeutic and diagnostic) hysterography and so on. After surgery or manipulation vaginal capsules continue to introduce a few more days.

Assign Polygynax usually one vaginal capsule at night for 12 days of treatment and 6 days for prophylaxis. Vaginal capsules are introduced as deeply as possible into the vagina.

Contraindications and side effects

Contraindications for use of vaginal capsules Polizhinaks are only individual intolerance of components and breast-feeding Breastfeeding - a personal choice   feeding.

During pregnancy Polizhinaks prescribed, but strictly on the evidence and only under laboratory control. Precautions Polizhinaks prescribed for severe renal impairment. If it is to take long courses or randomly, then it may have a systemic effect, which can be dangerous for kidney failure Kidney failure - when treatment is vital .

Side effects are only known allergic reactions, overdoses Polygynax observed.

Polizhinaks is an effective and easy-to-use drug. But, despite this, it can be used only under laboratory control.

Galina Romanenko

Today, not only the progesterone is released as before, in ampoules but in dosage forms for oral administration - tablets and capsules containing natural or synthetic progesterone. Therefore progesterone in injectable form is used nowadays less and less.

For what purpose can be used progesterone capsules

Progesterone - a female sex hormone that provides hormonal support for the second phase of the menstrual cycle and pregnancy. With a lack of this hormone may be in breach of the menstrual cycle, infertility, development of uterine bleeding associated with too much growth of the mucous membrane of the uterus (the endometrium) under the influence of female sex hormones estrogen (they support the first phase of the menstrual cycle), the development of fibrocystic changes in the breast (mastitis).

Lack of progesterone during pregnancy can result in miscarriage as progesterone inhibits contraction of uterine muscle and inhibits immune-processes that can lead to abortion.

Progesterone for intramuscular or subcutaneous injection is produced in the form of 1 and 2%, 5% oil solutions. It is introduced to restore a normal menstrual cycle, with a lack of progesterone. If it is not enough, in the body there is a relative abundance of the female sex hormones estrogen, which causes an increase in the volume increased (proliferation) of the mucous membrane of the uterus (the endometrium). When large amounts of endometrial rejected, there is a disorderly uterine bleeding, which may last for a long time, since the endometrium is peeled from the different parts of the uterus uneven. Such uncontrolled bleeding called dysfunctional, they can cause severe iron deficiency anemia in women.

In the absence of ovulation, menstruation and hypoplasia female genitals to form menstrual initially administered estrogen, progesterone and then, it can also be administered by injection.

Disadvantages of progesterone in ampules

The most important drawback of progesterone oily solutions, which are produced in capsules, is the inconvenience of application. Injections of progesterone oily solutions are very painful, sometimes at the site of administration of the drug occurs abscess - abscess or cellulitis.

Especially dangerous progesterone capsules for use during pregnancy: it increases the tension woman that is not conducive to the normal course of pregnancy. The threat of infection also makes injections of progesterone is extremely undesirable.

Therefore progesterone Progesterone - norm and pathology   ampoules now used less and less. Such drugs as utrozhestan Utrozhestan - corrects the deficiency of progesterone , Djufaston and others are available in dosage forms for oral administration and are full substitutes progesterone oily solutions for injection.

Contraindications

Contraindications progesterone capsules in case of hypersensitivity of the female organism to the drug, severe violations of liver and kidney function, increased blood clotting and a tendency to form blood clots, bleeding from the genital organs of unknown origin, spontaneous abortion, and after the 12th week of pregnancy.

Relative contraindications for the use of progesterone in ampoules (can be used, but with care) are diseases of the cardiovascular system (especially persistent high blood pressure), not heavy liver and kidney disease in violation of their function, diabetes mellitus Diabetes - threatening and incurable disease , Asthma, epilepsy, expressed headaches that occur in the form of attacks with a sharp sudden expansion of the blood vessels of the brain (migraine), depression, disorders of lipid metabolism, ectopic pregnancy, breast-feeding.

Possible side effects

Parenteral (bypassing the gastrointestinal tract) administering any drug gives more side effects than taking the same substance inside. Progesterone in this case is not an exception. At its intramuscular or subcutaneous administration, the following side effects:

• blockage by a thrombus or embolus (blood clot to break away) important blood vessels, such as cerebral vascular or pulmonary arteries, which can lead to the death of a woman;
• complications of the liver and bile ducts - stagnation of bile in the biliary tract and the formation of stones in them, hepatitis Hepatitis - the scourge of our time   against the backdrop of stagnation of bile;
• menstrual irregularities with the development of intermediate bleeding;
• swelling and engorgement, galactorrhea (spontaneous discharge from the nipple milk);
• alopecia, allergic reactions.

Progesterone in ampoules appointed doctor.

Galina Romanenko