The causes of endometriosis are still not fully established. It is believed that the disease appears in the background of hormonal imbalance, neuroendocrine disorders, failure in the body's defense system and more. The mechanism of development of endometriosis is associated with the spread outside the uterine lining cells that are on their morphofunctional properties are similar to the cells of the endometrium. Endometriotic lesions may develop in the organs of the reproductive system, and beyond. Endometriosis is difficult to treat and get rid of the disease is very difficult. But as you know, it is easier to prevent than to treat it. Prevention of endometriosis should be carried out not only to patients who have had the disease, but also the health of women, especially those who have a genetic predisposition to the development of endometrioid heterotopias.

Group risk of endometriosis

Gynecologists strongly recommend prevention of endometriosis, women who have the following factors:

• shortening the length of the menstrual cycle;
• heavy, prolonged menstruation and clotted;
• metabolic disorders (significant weight gain, obesity);
• use of intrauterine contraceptive (IUD);
• childbearing age (especially from 30 to 45 years);
• High levels of estrogen;
• family history (the presence of family history of endometriosis).

Preventive measures endometriosis

To prevent the occurrence of the disease or its recurrence help adherence prevention, which include:

• Food

Nutrition of women who are prone to the formation of endometriosis must be complete and include the necessary amount of protein, fat, carbohydrates, vitamins and minerals. It is advisable to increase the number of meals to five or six times a day, allowing you to maintain a healthy hormonal balance. There should be no consumption of coffee, strong tea and fizzy drinks (cola, lemonade, etc.). Smoking and alcohol should be abandoned.

• Prophylactic examinations

Every woman should keep in mind that a visit to a gynecologist should be applied at least twice a year. If necessary, the doctor will prescribe timely treatment of inflammatory gynecological diseases, and recommend the best methods to prevent unwanted pregnancies.

• Sports

One theory is the implantation of endometriosis, which explains the origin of the disease by throwing menstrual blood through the fallopian tubes into the abdominal cavity where endometrial cells are implanted, take root and form endometriotic lesions. Retrograde blood reflux promote active aerobics, gymnastics, figure skating, acrobatics, physical exercises Myths about exercise: do not believe   on sports equipment (bars, beam, horizontal bar, etc.). Therefore, physical activity should be strictly dosed and eliminated during menstruation.

• Relief of pain during menstruation

Algomenorrhea often contributes to retrograde blood reflux in the pelvic area. Get rid of the painful menstruation help antispasmodic drugs (baralgin, papaverine Papaverine - for pain caused by spasms of smooth muscles , No-spa, spazmalgon and others). Antispasmodics relax the muscles and muscular cervix, making the free flow of menstrual blood out of the uterus. Also, for the relief of pain are widely used non-steroidal anti-inflammatory agents such as indomethacin, which suppress prostaglandin synthesis. In some cases, it recommended the appointment of combined oral progestogen-estrogensoderjath drugs (Marvelon, Regulon, Rigevidon and others).

• Preventing abortion and diagnostic curettage of the uterus

Any intrauterine intervention is a predisposing factor for the development of endometriosis. It is necessary to carry out prevention of abortion, and dysfunctional uterine bleeding Uterine bleeding outside of menstruation - a sign of a serious breach   treat hormonal therapy, possibly avoiding the dilatation and curettage of the uterus Curettage - how dangerous it is? .

• The fight against obesity.
• Choosing the best method of contraception

To prevent the development of endometriosis as a contraceptive, it is desirable to use hormone pills (estrogen-gestagensoderzhaschie preparations and mini-pill). From the introduction of the intrauterine device should be abandoned.

Anna Sozinova

Polizhinaks - is an antimicrobial and antifungal drug that is used for the topical treatment of various infectious and inflammatory diseases of the vulva, vagina and cervical canal. It is also used prophylactically before surgical operations and manipulations in gynecology.

Mechanism of action

Polizhinaks - a drug with antibacterial and antifungal activity for topical application in gynecology, which is produced by the French pharmaceutical company Laboratory Innotech Internacional in vaginal capsules for local use.

The structure consists of three main Polizhinaks active substances: neomycin, polymyxin B and nystatin Nystatin - help with candidiasis . The excipient is present in each capsule gel dimethylpolysiloxane.

Neomycin (each capsule contains 35,000 IU neomycin) - is a broad spectrum antibiotic of the aminoglycoside, which has a bactericidal action against Gram-positive and especially Gram-negative bacteria. Polymyxin B - polymyxins group of antibiotics has a marked effect on gram-negative microorganisms. However, neomycin, and polymyxin B has a bactericidal effect (kills bacteria) against many gram-negative and gram-positive microorganisms of certain types of staphylococci, enterococci, E. coli, Proteus, and some other antibiotics.

Nystatin - an antifungal antibiotic Antibiotics - whether they will help you in the foreseeable future? It is particularly effective against fungi, yeast genus Candida.

Gel dimethylpolysiloxane has enveloping effect, relieves irritation and itching, improves metabolic processes in the wall of the vagina, facilitates the penetration of active principles Polizhinaks in the folds of the vaginal walls.

The combination of the main active ingredients allows Polizhinaks to cope with the bulk of the gynecological infections and prevent the development of candidiasis (thrush), which often develops in the treatment of such diseases.

With the introduction of vaginal capsules in the vagina Polizhinaks active substances are evenly distributed along the walls of the vagina, providing a local antibacterial and antifungal activity. They are practically not absorbed into the blood. The total effect on the body is only possible with prolonged uncontrolled use of the drug.

Indications and contraindications

Polizhinaks prescribed for the treatment of gynecological infectious and inflammatory diseases (vulva, vagina, cervical canal) caused by susceptible to the infectious agents. Treatment Polizhinaks subject:

• inflammation caused by nonspecific infection (staphylococcus, Escherichia coli and so forth, which cause the same type of disease symptoms);
• inflammatory processes caused by a fungal infection Fungal infection: to prevent and defeat ;
• inflammation caused by mixed infection.

In addition, Polizhinaks appointed prophylactically before gynecological surgery, childbirth, abortion, therapeutic and diagnostic procedures (eg before hysteroscopy).

Duration of appointment Polizhinaks must strictly comply with the established order not to develop resistance to it pathogens.

Contraindications for use Polizhinaks are individual intolerance of components and breast-feeding Breastfeeding - a personal choice   feeding.

Precautions Polizhinaks used during pregnancy and in patients with severe renal dysfunction.

Side effects Polizhinaks may appear as allergic reactions. Despite the fact that very few Polizhinaks absorbed when applied topically, when used for a long time, perhaps systemic effects, including toxic effects on the kidneys, which is characteristic for antibiotics - aminoglycosides. Perhaps the loss of efficiency Polizhinaks, if used together with spermicides (medicinal spermicides), so this combination drug is not recommended.

How to apply

Polizhinaks prescribed only after the laboratory tests to identify the pathogen and its sensitivity to the drug.

Vaginal capsules enter deeply in the vagina for one night. The duration of the treatment course - 12 days preventive - 6 days. During menstruation, the treatment is not interrupted.

Polizhinaks - it is quite effective when used correctly and safe drug which can be used only on prescription and under laboratory control.

Galina Romanenko