Antibiotics - are drugs having high efficacy in the treatment of infections and infectious and inflammatory diseases. Receiving another means, have a significant effect on the body, reduce the effectiveness of any antibiotic. In addition, the combination of specific antibiotics with alcohol has its own individual characteristics.

What happens if you consume alcohol during treatment with amoxicillin

All spirits have toxic effects on the human body, they are able to intervene in cellular metabolism Improves metabolism and losing weight without dieting By changing it depending on the dose. Particularly negative impact alcohol has on cells of the central nervous system and liver.

Especially decrease therapeutic effects of amoxicillin while taking alcoholic beverages.

A combination of amoxicillin with alcohol may have an adverse effect on the liver, the respiratory system, enhance allergic reactions, side effects from the gastrointestinal tract, central nervous and cardiovascular systems. In addition, it is possible the emergence disulfiramopodobnyh reaction.

The effects from the digestive organs

Amoxicillin can have side effects from the gastrointestinal tract such as nausea, vomiting, diarrhea, pain during bowel. Alcohol, particularly strong, also has a negative effect on the gastrointestinal tract, resulting in all the side effects of amoxicillin increase.

But the main negative impact of the combination of amoxicillin with alcohol has on the liver, as both have hepatotoxic effects. The extent of the impact will depend on the doses and strength of alcohol taken, and from individual to individual, including from his inheritance. Therefore, not the fact that if one patient this combination will not cause significant harm, as it will be with other patients. It can result in severe consequences in the form of toxic hepatitis Toxic hepatitis - the impact of harmful substances on the liver .

The effects of the respiratory system

Amoxicillin can cause shortness of breath - it has a side effect. Alcohol can depress the respiratory center in the brain, which often is the cause of death in severe intoxication. Therefore, while taking amoxicillin and alcohol-disordered breathing is a risk, especially if the lung or bronchi currently there is an inflammatory process.

Of course, if you drink a little wine, such a risk is negligible, but is it worth doing?

Strengthening of allergic reactions

Amoxicillin - is an antibiotic that belongs to the group of semisynthetic penicillins. The whole group of these drugs has increased ability to cause allergic reactions, and therefore they are not recommended to appoint allergic diseases such as asthma, hay fever, atopic dermatitis and so on.

Allergic reactions can be worn at the same time is very severe. But the most unpleasant that they suddenly arise and require immediate medical attention.

The effects of the central nervous and cardiovascular systems

How amoxicillin and alcohol affect the central nervous system, and what will be the result of this action, it is difficult to predict.

On the part of the cardiovascular system with a combination of amoxicillin with alcohol may appear tachycardia Tachycardia - the body to the limit?   - Both substances contribute to its occurrence. Infectious and inflammatory processes can further strengthen tachycardia.

Disulfiramopodobnyh reaction

Disulfiram (teturam, Antabuse, esperal) - a drug used in the treatment of chronic alcoholism. It destroys the enzyme which neutralizes the toxic products of metabolism of alcohol. As a result of these toxic metabolic products accumulate in the body and cause certain symptoms: a sharp drop in blood pressure, shortness of breath, tinnitus, tachycardia, nausea, vomiting and so on. This reaction is called disulfiram-alcohol.

Enzyme may block the action of some other substance - such reactions are called disulfiramopodobnyh. Substances causing disulfiramopodobnye reactions include some antibiotics such as cephalosporin antibiotics, in their chemical structure similar to the semi-synthetic penicillins. Therefore, while taking amoxicillin and alcohol to eliminate the appearance of such a reaction can not be.

Amoxicillin, as well as any other drugs with alcohol is better not to combine.

Galina Romanenko

Amoxiclav - a modern, extremely efficient antibiotic that is used for a variety of infectious and inflammatory diseases. Despite its high activity, amoksiklav safe enough antibiotic, it is allowed to use, even for pregnant women.

The mechanism of action amoksiklava

Amoxiclav - a comprehensive broad-spectrum antibiotic that produces the Swiss pharmaceutical company "Sandoz" in tablets for adults, suspensions, and drops for children and as a powder for solution for injection in vials. The composition includes amoxiclav amoxicillin (antibiotic group semisynthetic broad-spectrum penicillins) and clavulanic acid - a substance that inhibits the enzyme activity of beta-lactamase makes amoxicillin resistant to this enzyme.

Beta-lactamases - enzymes that are produced by some infectious agents and inhibit the activity of antibiotics penicillin group. Thus, the combination amoksiklava klavlonovoy acid is a broad-spectrum antibiotic, resistant to enzymes destroying traditional antibiotics of the penicillin group. Clavulanic acid itself also has little antimicrobial activity.

For sensitive Amoksiklava many microorganisms, including beta-lactamase producing, protecting them from the effects of penicillin. This gram-positive bacteria - some species of streptococci and staphylococci, gram-negative bacteria - Escherichia coli, Gardnerella, Haemophilus influenzae, Helicobacter pylori, Klebsiella, Clostridium.

After taking the pill amoxiclav rapidly absorbed from the intestines (ingestion of this process is not affected). Amoxicillin is absorbed better than clavulanic acid, maximum concentration in blood is achieved within an hour. Next antibiotic distributed to tissues and body fluids, penetrates into the maxillary and frontal sinuses, tonsils, auditory organ tissue, saliva, pleura and bronchopulmonary structures, genitourinary organs, bile duct. Amoxiclav not penetrate into the brain tissue if the meninges are not inflamed, but cross the placenta and are excreted in human milk. Thereafter, the drug is partially decomposed into products of metabolism and is excreted in the urine, which creates high concentrations in the urine.

Indications and contraindications for the appointment amoksiklava

Amoxiclav appoint the following infections caused by susceptible to the pathogens:

• upper respiratory tract and upper respiratory tract - acute and chronic sinusitis, frontal sinusitis, otitis, tonsillitis;
• bronchopulmonary system - acute and chronic bronchitis, pneumonia, pleurisy;
• urogenital infections - acute and chronic pyelonephritis, cystitis, gynecological infections,
• soft tissue infections, skin and mucous membranes;
• infections of bones and joints;
• biliary tract infections;
• periodontal tissue infections.

Amoxiclav contraindicated:

• in hepatic dysfunction, which occurred earlier in patients receiving amoksiklava;
• under the age of 12 years (tablets);
• if you are hypersensitive amoksiklava components and antibiotics penicillin group;
• in infectious mononucleosis Infectious mononucleosis - the illness of students   (skin rash in infectious mononucleosis Mononucleosis - forecast favorable   similar to an allergic rash that occurs when taking amoksiklava);
• lymphocytic leukemia.

With care prescribe a drug to patients with inflammatory bowel disease, severe liver disease and kidney with a violation of their functions. When pregnancy amoksiklav Amoxiclav - an effective tool against infections   apply only if the expected benefit to the pregnant woman than the potential risk to the fetus.

Side effects that can occur when taking an overdose and amoksiklava

When receiving amokiklava, the following side effects:

• from the gastrointestinal tract - loss of appetite, nausea, vomiting, diarrhea;
• of the liver and kidneys;
• the central nervous system - dizziness Dizziness - if the ground is slipping from under his feet , Headache, convulsive readiness;
• from the blood - a decrease in the number of blood leukocytes, platelets, hemolytic anemia (decreased red blood cell count due to their bonding), decrease of blood coagulation;
• on the part of the urinary tract - interstitial nephritis, formation of stones in the urine;
• Allergic reactions such as skin rash, including with urticaria angioedema.

Overdosing is manifested in the form of gains of all side effects. It should be gastric lavage and seek medical advice. In severe cases of overdose patients are hospitalized.

Action amoksiklava slows down while taking with medications that reduce stomach acid, laxatives is slowing, with ascorbic acid - increases.

Amoxiclav - quality modern antibiotic with minimal side effects.

Galina Romanenko