Betaserk - analogs of this drug for the treatment of diseases of the vestibular apparatus produces several pharmaceutical companies under their own names. Common to all of these preparations is the active substance - betahistine - a synthetic analogue of histamine.

Analogs betaserk - what is the difference from the original?

Analogues in the pharmacy called drugs, the effect of which is similar to each other. This active substance of such drugs may be different. Pharmaceutical formulations with the same active substance are called synonyms. However, it is synonymous among the amateurs are called peers. Such analogs (synonyms) is completely interchangeable - you need only to specify the dosage of active principle.

So what betaserk different from their counterparts, of which there are about a dozen? It alfaserk, asniton, Betaver, betahistine, betahistine hydrochloride, betagistamina dihydrochloride betatsentrin, vazoserk, vestibo, vestikap, denoyz, micrograins, tagista.

This company opened a chemical formula of active principle (betahistine - a synthetic analogue of histamine), its mechanism of action on human conducted numerous studies, first in the laboratory on animals and then on human volunteers suffering from diseases of the vestibular apparatus, to calculate the dosage of the drug, revealed side effects and established the indications and contraindications for its use. This preparation is called an original. For the release of the original drug it takes years of labor, highly qualified specialists, modern equipment and a chemical substance with a minimum amount of impurities. That is why the original drug is the best. But it is usually the most expensive.

All other pharmaceutical companies took advantage of ready developments Abbott and produced the same products under its own name. These drugs are called generics. The difference between the original and the generic can be very significant, and can not be no - it all depends on how production is organized, and how the pure chemical is used to produce the drug.

The cost of the original and generic drugs

The original drug betaserk available in tablets of 8, 16 and 24 mg. Betaserk 8 mg (30 tablets) is worth more than 400 rubles, 16 mg (30 tab.) - Almost 600 rubles, 24 mg (20 tab.) - About 550 rubles.

The most popular in our country counterparts betaserk Betaserk - a drug that helps restore the balance   betahistine are, Betaver, tagista, vestibo.

• Betahistine (Kanonfarma pharmaceutical company, Russia) is available in tablets of 24 mg, 20 tablets costs about 140 rubles.
• Pharmaceutical company Makiz Pharma (Russia) releases the drug tagista (active substance - betahistine) in tablets of 24mg. 30 tablets tagisty costs just over $ 100.
• Domestic pharmaceutical company Ozone produces not tablets and capsules under the name vestikap (active substances in them is also betahistine) on 8 and 16mg. 30 capsules vestikapa 8 mg costs about 150 rubles, and 30 capsules of 16 mg - slightly more than 200 rubles.
• Betahistine and produces one of the oldest domestic pharmaceutical companies - Veropharm (today it is part of the international concern STADA) is also under his name - Betaver in tablets of 8, 16 and 24 mg of 20-30 tab. It costs from 140 to 180 rubles.
• Popular is also the generic vestibo - a drug that makes the Icelandic pharmaceutical company Actavis. It is available in tablets of 16 and 24 mg. 30 tablets of 16 mg costs about 200 rubles, 30 tablets of 24 mg - 250 rubles.

Which drug to choose - the original or generic?

But it will advise the doctor. Of course, the best is considered to be the original, however, and the price of drugs is also important, especially if the patient has to take it for a long time. Very often vertigo develops in old age, when a person has to rely on his pension.

Betaserk and all its analogs (more correctly - synonyms) help patients to cope with vertigo Dizziness - if the ground is slipping from under his feet   and stable hearing loss - the main features of diseases of the vestibular apparatus.

Galina Romanenko

In the scientific literature there is no description overdose glycine, because this amino acid is the drug that is contained in the human body - it is involved in the metabolism of the brain cells. But it is wrong to assume that the more glycine to take, so it is more efficient.

On what is the effect of glycine

Glycine (aminoacetic acid) is found in many biologically active substances and proteins as an amino acid. Glycine has a positive effect on metabolism Improves metabolism and losing weight without dieting   cells in the tissue of the brain and spinal cord (neurons), increasing their capacity in glucose uptake. Assimilation of additional amounts of glucose in turn helps to activate all other kinds of metabolism in the central nervous system (CNS). For the recovery of neurons following various effects (trauma, intoxication, stroke and so on) is very important metabolic activation protein, and this contributes to glycine. It also protects neurons from damage by various toxins and free radicals.

Glycine also inhibits the action of adrenaline - a substance that causes the body to "combat readiness" by activating an ancient mechanism of resistance to the enemy, which can be briefly described as "fight or flight". Under the action of adrenaline constricted blood vessels, increased blood pressure (BP), heart rate increases, the number of respiratory movements, the activities of the central nervous system is activated. Suppressing effect of adrenaline, Glycine has a calming effect, it reduces all vegetovascular symptoms: decreased blood pressure, decreased tachycardia Tachycardia - the body to the limit? Restored the normal number of respiratory movements, increased sweating passes. But, in addition, glycine promotes the development of an additional amount of GABA (gamma-aminobutyric acid), which also has an inhibitory effect on the CNS.

Thus, glycine has neuroprotective (protects neurons), detoxifying, anti-oxidant, soothing effect on the central nervous system. It operates fairly slowly, however, the effectiveness of the drug is proved by numerous studies. It soothes, relieves mental stress, aggression, conflict, increases their chances of social adjustment. In addition, it reduces the depression Depression - a little more than a bad mood , Restores normal sleep, increases mental performance. Severe central nervous system (including stroke and the destructive effect of alcohol on the brain) it reduces the severity of brain disorders.

In what doses taken

Despite the fact that glycine is included in the tissue of the human body and can improve brain functions, it would be wrong to think that the higher the dose, the more efficient it is. Today designed instructions (including dosage) of the drug for use in various conditions and diseases. Nevertheless, more and more researchers are starting to take the view that the doses of glycine should be individualized, as different organisms need this stuff in different amounts due to the individual characteristics of metabolism.

Basically, it is used for one tablet (0, 1 g or 100mg) two to three times daily for two to four weeks. The tablet is placed under the tongue and held there until complete resorption. You can put the tablet on the cheek or grind it into a powder and also put under the tongue or cheek. After some time on the recommendation of a physician treatment can be repeated. So appoint a glycine with a decrease in mental performance, emotional and high information loads, reducing memory, concentration, as well as mental retardation in adolescents and in chronic alcoholism.

Children up to three years from the effects of perinatal (except in the second half of pregnancy, during childbirth and in the first week after birth) brain lesions and traumatic brain injury each appoint half of the pill (0, 05 g or 50 mg) two or three times a day. Treatments - one to two weeks, and then half a tablet given once a week. Throughout the course of treatment the child up to three years is prescribed 2 to 2, 6 g glycine. Children older than three years receive the same dose as adults.

When insomnia or sleep violation of glycine take 20 minutes before sleep Dreams: how to understand our dreams   or just before bedtime. Children under three years are half a tablet, and over three years old and adults - on a tablet under the tongue.

Large doses of the drug are shown only in the first days after an ischemic stroke. In this case, the maximal effect of glycine is obtained from the destination in the first three to six hours after a stroke. The patient for five days administered glycine at 1 g (10 tablets of 100 mg) by dissolving it in a small amount of water. From the 6th to the 30th day of illness glycine is assigned to one or two tablets three times a day.

An overdose of high doses of glycine does not happen, but it is necessary to monitor the patient's blood pressure, since glycine may help to reduce it. If the patient has low blood pressure, in large doses, it is not necessary to appoint a glycine.

Galina Romanenko