Citoflavin affect the pathological changes associated with metabolic diseases of the central nervous system, respiratory hypoxia and hypoxia of the heart muscle, changes in acid-base balance, the weakening of protection against the effects of free radicals and activation of lipid peroxidation. Citoflavin prevents cytolysis and cell death, as well as stimulate cell regeneration.

Indications for its use are:

• Stroke (cytoflavin used to treat the effects of stroke, in particular, chronic cerebral ischemia)
• Vascular encephalopathy (stages 1-2)
• Toxic and hypoxic encephalopathy with acute or chronic poisoning, endotoxemia, and depressed consciousness after anesthesia
• The vials contain 10 ml cytoflavin drug. Before use, 10 ml cytoflavin be diluted 100-200 ml 5-10% glucose solution Glucose: The energy source   (preferred) or 0.9% sodium chloride solution. The resulting solution can be administered only intravenously.

The properties of the drug

• It is a combined medication, which is composed of natural metabolites, co-enzymes and vitamins
• It has anti-inflammatory and antioxidant action
• It improves the oxidative metabolism under hypoxic conditions
• It stimulates the activity of adenylate cyclase
• Activates the intracellular synthesis of nucleic acids
• It improves glucose utilization, synthesis and intracellular accumulation of ATP (adenosine triphosphate) and other compounds vysokoenegreticheskih
• It improves blood oxygen saturation
• It restricts the area of ​​ischemic damage and stimulates the regenerative processes
• It stimulates cellular respiration and energy production
• It improves utilization of oxygen by body tissues
• Restores antioxidant enzymes
• It improves utilization of fatty acids and re-synthesis in neurons of gamma-aminobutyric acid (GABA)
• Improves coronary and cerebral blood flow
• Activates metabolic processes in the central nervous system
• It has a beneficial effect on mental activity
• It reduces the time of awakening after surgery under general anesthesia
• Admission cytoflavin within 12 hours after stroke:
• It reduces the amount of ischemic and necrotic lesions
• It reduces neurological deficit
• Significantly reduces the likelihood of disability in the long run
• It has antihypertensive effect
• It has a cytoprotective effect
• It affects the inflammatory processes

The mechanism of action cytoflavin

Antihypoxia and antioxidant properties cytoflavin determined by complementary actions of succinic acid, inosine, nicotinamide and riboflavin (sodium phosphate).

Succinic acid and inosine (the main active substances cytoflavin) absorbed immediately after the introduction of the solution. Most of inosine liver converts into uric acid Uric acid - a normal level? ; remnants of the substance excreted through the kidneys.

Nicotinamide is rapidly distributed to all tissues, it is processed by the liver into nicotinamide-N-pyrrolidinone and excreted through the kidneys. He also appears in breast milk in nursing mothers.

Most riboflavin enters the myocardium, liver and kidney; it can also be output in breast milk.

Contraindications

Citoflavin can not be taken by pregnant or lactating women. It is also contraindicated in patients with individual intolerance to components of the medication.

• Side effects
• Cytoflavin have observed the following side effects:
• Lowering blood sugar levels
• Worsening symptoms of gout Gout - the "disease of kings"   (usually occurs when chronic administration of the drug at high doses)
• Hyperuricemia
• Itching
• Hot flashes and dry mouth (seen in the administration of the wrong drug, speed)

In the process of metabolism Metabolism: The basis of life of all living things   Energy is extracted from the environment and convert it into energy materials, the decay of which (in the course of redox reactions) energy is released, providing the vital processes. This allows to obtain energy from food intermediates, which will later be the basis for the production of proteins, fats and carbohydrates - the components of human cells.

What is the EEG of the brain? Electroencephalography, or EEG - a method for measuring and recording the electrical activity of the brain. During the EEG of the brain to the human head attached special sensors (electrodes) connected to the computer. Computer displays indicators of brain activity in the form of curves on screen or on paper.

What held the EEG of the brain?

EEG can be used to:

• Diagnosis of epilepsy Epilepsy - a sacred disease Usually - to determine its type;
• The definitions of brain death in patients who are in a coma;
• Studies of sleep disorders such as narcolepsy;
• Observing brain activity in patients in the handling of the brain;
• Diagnosis of dementia;
• Diagnosis of brain tumors, head injuries, brain abscesses, and encephalitis.

In addition, for the detection of certain dangerous diseases can be used and the procedure, which is sometimes mistakenly called EEG brain vessels - rheoencephalography (REG). To perform this diagnostic procedure to the person's head and electrodes are attached, but not REG measures the electrical activity of the brain, and to evaluate the state of cerebral vessels - their elasticity, tone, and so on.

Prepare for the EEG brain

During the conversation, during which the doctor discusses with the patient the details of the EEG, be sure to tell the doctor about any medications you are taking. He may ask you to stop taking certain drugs (eg, sedatives, tranquilizers, muscle relaxants, hypnotics or antiepileptic drugs) some time before the EEG. These medicines can affect the electrical activity of the brain, which is why the result of the EEG is not completely reliable.

Twelve hours before the procedure should not eat foods that contain caffeine (coffee, tea, cola and chocolate and energy drinks).

Because the electrodes are attached to the scalp, the hair and the skin should not be free of oils, lotions, creams and other products containing fats. In the evening or in the morning before the EEG wash your hair, and then do not use any conditioners, gels, paints and other cosmetics for the hair.

If such a procedure will make your child, you also have to stay awake and watch out for, so that he did not sleep more than necessary. Sent to the EEG after a sleepless night or too short sleep better public transport or a taxi (or have someone from the family to bring you to the hospital).

How is the EEG

EEG can be performed in hospitals, clinics or specialized medical centers. Deciphering electroencephalogram engaged neurologist - a doctor who specializes in diagnosing and treating diseases of the nervous system Diseases of the nervous system - the basic classification .

During EEG patient lies on his back, on the couch or on a special table, or sitting in a chair with his eyes closed. By the scalp of the patient in several different locations fastened flat metal disc - electrodes; that they kept and did not fall, a special sticky paste. Instead, the head of the patient can wear a helmet, in which the electrodes are already fixed.

During the procedure, patients must lie still, eyes closed, and not to talk, if they are not treated. Often the patient is alone in the room where the EEG is performed, and a specialist was watching him through the glass. The procedure can be periodically interrupted, the patient can move around a little bit and change posture.

Sometimes the doctor asks the patient in the course of the EEC to perform certain actions in order to evaluate how this changes the activity of the brain. For example, he may ask you to breathe deeply and quickly - usually have to do twenty breaths per minute for three consecutive minutes, or look at a bright flashing light (called stroboscopic stimulation). Finally, the patient may be asked to go to sleep; If for some time to do this is impossible, it is given drugs with a sedative effect. In the diagnosis of sleep disorders Dreams: how to understand our dreams   EEG can be carried out throughout the night - in such cases, the patient has to sleep in the hospital.

EEG of the brain in children is carried out as well as adults, but presents some difficulties, as the children are concerned in an unfamiliar environment, and this is reflected in the test results. That during the procedure the child was quiet, parents should be prepared in advance it to the EEG to describe the room where it will be held, to say that it does not hurt that mom or dad will be there, and that this survey is very important for the baby's health. During the EEG parents are usually allowed to stay with the child.

What is felt by the patient during the EEG

EEG - a completely painless procedure. If the patient is asked to breathe deeply and frequently, it may feel a little dizzy Dizziness - if the ground is slipping from under his feet   and / or numbness in the fingers. This is - a normal reaction to hyperventilation, and your condition will return to normal within a few minutes after you start breathing normally.

If the attachment of electrodes used a special paste, a small quantity may remain on the hair after the procedure. It is easily washed off with shampoo and warm water.

The only discomfort during the EEG is usually due to the fact that the patient has to lie down or sit still for quite a long time, or sleep under the supervision of strangers. However, by the EEG should be treated as a normal procedure, which is carried out for the sake of your own health - after all, this is not the most unpleasant of all diagnostic procedures.