Treatment of sinusitis should be aimed at reducing the duration of illness, prevention of complications and destroy microorganisms that cause inflammation of the sinuses. Antibiotics - those pills sinusitis who are coping with these problems.
When antibiotics are needed in the sinus
Antibiotic therapy is prescribed not all patients sinusitis
Sinusitis - when a puncture is required
But only with moderate and severe forms of the disease. In order to determine whether these drugs to a patient, the doctor assesses its general condition and complaints, conditions and duration of sinusitis, as well as examining the nasal passages.
Acute sinusitis is better to treat with antibiotics than chronic. If the sinuses there is pus, the effectiveness of these drugs will be less.
Penicillin
Amoxicillin - a drug that is often chosen in the treatment of sinusitis
Sinusitis - the treatment may only be carried out under the supervision of a physician
. It relates to semisynthetic penicillins and is active against many bacteria. However, some strains of microorganisms produce penicillinase (enzyme that destroys these antibiotics), and thus they are resistant to amoxicillin.
If three days after the start of treatment the patient does not feel better, you should start using another antibiotic. In this case, prescribers, which include amoxicillin and clavulanic acid:
- Femoklav Soljutab;
- Amoxiclav Kviktab;
- Augmentin.
Clavulanic acid binds with penicillinase as a result of the interaction of the enzyme loses its activity is not destroyed, and amoxicillin. Clavulanic acid also has an independent antibacterial activity.
Macrolides
Macrolides - drugs that are prescribed to patients intolerant of antibiotics penicillin. Sumamed and macrofoams - members of this group.
Macropen (midecamycin) suppresses the formation of protein in bacterial cells. In small doses, it inhibits the reproduction of microorganisms, and in large - destroys them. The drug is contraindicated in patients with severe hepatic impairment and in case of hypersensitivity to it. Precautions macrofoams used during pregnancy and in patients who in the past had an allergic reaction to acetylsalicylic acid.
Sumamed (azithromycin) - an antibiotic which has a broad spectrum of activity (impact on the livelihoods of many microorganisms). It has bacteriostatic action, that is, helps stop the breeding of germs. Sumamed not used in people with severely impaired kidney and liver function, during lactation, and in case of hypersensitivity to macrolide antibiotics. The drug should not be taken simultaneously with ergotamine and dihydroergotamine.
Fluoroquinolones
The drugs in this group are assigned to those patients who have the first course of antibiotic therapy was unsuccessful. Levofloxacin and moxifloxacin - fluoroquinolones, which are used to treat sinusitis.
Levofloxacin violates the formation of DNA of bacteria, causes significant changes in their cell wall and cytoplasm, and the microbes die from it. The drug is contraindicated in case of hypersensitivity to any fluoroquinolone, epilepsy
Epilepsy - a sacred disease
, Pregnancy and lactation. Due to the high probability of decline in renal function elderly people should take levofloxacin under the supervision of a physician.
Moxifloxacin has the same mechanism of action and contraindications. This antibiotic should be used with caution in central nervous system diseases which predispose to occurrence of seizures, with severe liver failure, low concentration of potassium ions in the blood and bradycardia
Bradycardia - when the heart stops
.
Fluoroquinolones are not applicable in children and adolescents, as they adversely affect the growth of cartilage and connective tissue. Therefore, such patients received macrolides.
Antibiotics - the mainstay of treatment of sinusitis. But these drugs should not be used on their own, without consulting a doctor. The doctor must inform about other existing diseases and medications that the patient is taking.