Diseases of the joints have become a symbol of our time, often they do not occur only in the elderly, but also young people, depriving them of health. For the treatment of diseases of the joints produced special medicines, such as alflutop Alflutop: drug for the treatment of joints .

The mechanism of action of Alflutop

Alflutop - a drug that improves metabolism Improves metabolism and losing weight without dieting   in cartilage and reduces inflammation in the area by the braking action of biologically active substances that contribute to its appearance (mediators of inflammation).

Available alflutop Romanian pharmaceutical company Biotehnos SA in ampoules as a solution for injection. Each ampoule Alflutop is a standardized, low-fat biologically active extract of the four species of small marine fish - sardines, whiting Black Sea, Black Sea shad and anchovies Black Sea. The extract contains a number of useful for metabolic substances - mucopolysaccharides (eg hyaluronic acid, able to attract water), chondroitin, dermatan, keratan, amino acids and their degradation products, as well as minerals such as sodium, potassium, calcium, magnesium, iron, copper and zinc.

The mechanism of action of Alflutop is that it prevents the disruption of normal cartilage and bone tissue, stimulates recovery of connective, bone and cartilage tissue, providing the most analgesic effect.

The anti-inflammatory effect and tissue repair based on suppression of activity of hyaluronidase - an enzyme that breaks down hyaluronic acid. Aflutop also stimulates the metabolism in tissues, especially in cartilage, thus preventing the occurrence of metabolic disorders in them.

Alflutop reduces the permeability of the walls of small blood vessels (reduces swelling), inhibits the formation of inflammatory mediators (reduced degree of inflammation), prevents the destruction of the connective tissue, stimulates the restoration of articular cartilage.

Included in the Alflutop biologically active substances have a positive effect on the tissue trophism, increase their ability to attract water (this is very important for metabolic diseases) and help to increase the height of the cartilage in the joints.

Alflutop able to significantly reduce the inflammation in the joints, including not only improve the clinical, and laboratory parameters. Under its influence in the joints increases the amount of hyaluronic acid. The anti-inflammatory and analgesic effect of the drug is in the second week of treatment.

Another property Alflutop connected with the work of the digestive system. Under its influence increases the amount of biologically active substances prostaglandins that protect the stomach lining from injury. Therefore, the drug has been applied for the prevention of complications in the gastrointestinal tract, resulting in long-term use of nonsteroidal anti-inflammatory drugs (they are almost always prescribed for diseases of the joints), which cause erosive and ulcerative his defeat.

Indications and contraindications for use

Indications for use Alflutop are:

• degenerative-dystrophic (metabolic) diseases of the joints: primary and secondary osteoarthritis, including after acute joint inflammation, arthritis of small joints, including the background of metabolic disorders;
• degenerative-dystrophic (exchange) of the spine: osteochondrosis Osteochondrosis - learn how to properly distribute the weight , Spondylosis;
• periarthritis - inflammation in the periarticular tissues;
• conditions after injuries and operations on the joints;
• violations of the processes of ossification of the joints;
• periodontal disease (periodontal tissue) - contributes to the restoration of periodontal tissue.

Contraindications alflutop at:

• hypersensitive to the components of the drug;
• Pregnancy and breast-feeding;
• at the age of 18 - no data on clinical trials in these patients.
• Side effects that may occur during the treatment and overdose Alflutop
• When treating Alflutop, the following side effects:
• skin irritation, accompanied by redness, slight swelling and itching at the injection site;
• pain in muscles and joints after the injection can be strengthened somewhat;
• allergic reactions, up to anaphylactic shock.

Overdose Alflutop manifested mainly in patients with allergic diseases or prone to allergic reactions. This enhancement of side effects. Alflutop generally well tolerated, including the simultaneous administration with other drugs.

Galina Romanenko

Alflutop is a means of regulating the metabolism Improves metabolism and losing weight without dieting   in cartilage, also possess anti-inflammatory properties. It prevents the destruction of joint cartilage and promotes regeneration. But at the same time as any material of animal origin, it may cause allergic reactions.

Features action Alflutop

Alflutop is a standardized, low-fat and deproteinized (devoid of animal protein) extract of the four species of sea fish. It contains a large number of biologically active substances that stimulate metabolism of cartilage and bone, as well as improve the circulation and reduce inflammation.

It is used in degenerative diseases of joints and spine. Unlike other drugs of this group is the natural means alflutop animal origin.

What side effects may cause alflutop

As with any drug of animal origin (even though it has been thoroughly cleaned of fat and protein) alflutop may cause allergic reactions. Thus allergies can be at a slight allergic rashes, including urticaria, which runs independently and in a severe allergic reactions of the immediate type.

For example, the possible spread of urticaria and its transition into angioedema, which captures the area of ​​the larynx and vocal cords. This could stop breathing. It is also possible anaphylactic shock with loss of consciousness, requiring immediate medical attention. Therefore injections Alflutop better to do in a medical institution, at least the first few treatments until confidence in its portability normal.

Furthermore, after injection Alflutop may cause redness, itching, and burning at the site of injection and the appearance of transient muscle pain. In some cases, the introduction of Alflutop directly into the joint may also increase in joint pain, which eventually passes and does not require discontinuation of therapy.

In overdose Alflutop in patients with allergic attitude may cause severe allergic reactions like anaphylactic shock. In this case, the patient required emergency medical treatment.

This is contraindicated alflutop

First of all, alflutop contraindicated if you are hypersensitive its components. If after the injection there any allergic reaction, even a minor, the next injection should be canceled - it is possible that it will cause is much more severe allergic reaction. Alflutop contraindicated and if the patient has an allergy to marine fish or seafood.

Alflutop not prescribed to pregnant women - clinical study on this cohort of patients with no reason. In addition, the body of a pregnant woman, and so constantly suppresses allergic reactions in relation to the tissues of the fetus and the additional allergen will not go in her favor.

This drug is contraindicated during breast Breastfeeding - a personal choice   feeding, since it is not established, whether it is released in breast milk and the like affects on the body of an infant Baby man, though with a little finger .

In childhood and adolescence alflutop also does not apply because of the fact that there is no information that would confirm the safety and efficacy of the drug.

How to apply alflutop

Alflutop prescribed for adults patients with degenerative-dystrophic lesions of joints and spine. The drug is available in vials as a solution for injection, it is introduced as deeply as possible into muscle, or directly into the joint. In some cases, spinal diseases doctor prescribes medication administration paravertebrally - right next to the spine on both sides. This method of administration is particularly effective in severe pain associated with compression of the spinal nerves.

When multiple lesions of joints and spine alflutop administered by deep intramuscular injection of 1 mg (10 mg) once a day. On a standard course of treatment is sufficient 20 injections. If arthrosis struck large joints, it is administered into alflutop joints injections made twice a week for 1 - 2 ml (10-20 mg) every modified joint. On Course - 5-6 injections in a particular joint, then move on intramuscular injection for three weeks.

After such a course are reduced pain, inflammation and partially restores the function of the joints and spine. But the miracle of Alflutop not wait: as well as any medications that affect the metabolism Metabolism: The basis of life of all living things It acts slowly.

Repeat treatment Alflutop can be 3-6 months.

Galina Romanenko