- Treatment of joints - which method is most effective?
- Pain relief
To avoid pain and joint damage, start to control the disease as early as possible. If you are diagnosed "rheumatoid arthritis", the first two years of treatment, follow these general guidelines. The body of each person is unique, so discuss with your doctor whether you approach this sequence.
What to do
When the first symptoms. Make an appointment with a therapist for a diagnosis. To determine the damage to the joints using X-ray or MRI. Prediction is determined depending on the age, results of analyzes, the presence of other rheumatic diseases, lung injury, heart, spleen, or blood vessels.
During two months. Typically, the first means, prescribed for rheumatoid arthritis, methotrexate is. Its effect is noticeable within one to two months, so the first time you can also use nonsteroidal anti-inflammatory drugs (NSAIDs) or analgesics, methotrexate is not to act.
During the six months. If methotrexate does not work, your doctor may prescribe another antirheumatic agent or biological agent added. Analysis of liver function should be performed every one to two months, if you are taking Arava, methotrexate or Remicade, periodically, if you are prescribed cyclosporine, once a year, if you are taking salicylates or other NSAIDs.
In a year. If the tests and examinations show that the disease progresses, there are joint damage, your doctor may prescribe stronger medications.
In two years. Each time the doctor should assess the development of the disease. Discuss the effectiveness of treatment and any health problems with a professional.
Always. Regardless of the treatment period, make sure health. It is useful to obtain as much information about the disease, do regular exercise, lose weight, if necessary, to be socially active and protect joints.
Drugs for Rheumatoid Arthritis
For the treatment of rheumatoid arthritis is used a lot of drugs. Some of them improve the symptoms of the disease, while others are designed to slow or stop the course of the disease and prevent joint damage. Most drugs are one of the following categories.
NSAIDs - non-steroidal anti-inflammatory drugs (NSAIDs, or - non-steroidal anti inflammatory drugs) - more than a dozen different drugs (some are sold freely, while others - only by prescription), which are used to reduce pain and inflammation in arthritis. Among NSAID drugs such as ibuprofen
Ibuprofen: anti-inflammatory drug
(Advil, Nurofen), ketoprofen (Ketonal, Flamaks) and naproxen (Aleve). If you have had a stomach ulcer or likely
Gastric ulcer - such dangerous snacks
, Your doctor may prescribe celecoxib (Celebrex), which is less harmful to the stomach.
Corticosteroids - Corticosteroids, including prednisone, prednisolone
Prednisolone - against inflammation, allergy and pain, but with complications
and methylprednisolone - is powerful and potent anti-inflammatory drugs. In rheumatoid arthritis, they can be used to control possible damage caused by inflammation in the initial phase of treatment has not yet become effective NSAIDs and DMARDs. Because of potential side effects, doctors try to prescribe corticosteroids in minimal doses and short-term.
DMARDs - Basic anti-inflammatory drugs work slowly, but do affect the course of the disease. In recent years, the most popular of these drugs is methotrexate. However, in this category there are also other drugs, such as hydroxychloroquine (Plaquenil), sulfasalazine, leflunomide (Arava) and azathioprine (Imuran). Doctors are trying to prescribe DMARDs as soon as possible after diagnosis, because it can help prevent irreversible joint damage.
Biological agents - is the latest means. For the treatment of rheumatoid arthritis
Rheumatoid arthritis - debunking myths about the disease
approved six such funds - abatacept (Ourense), adalimumab (Humira), anakinra (Kineret), etanretsept (Enbrel), infliximab (Remicade) and rituximab (Rituxan). Each of these drugs is blocking a separate stage of the inflammatory process. Humira, Enbrel and Remicade block cytokine called TNF-alpha. Kineret blocks the interleukin-1. Orensakh blocks T cell activation. Rituxan blocked B-cell. Since these drugs are directed to the individual steps of the process, they do not suppress the entire immune response, as some other drugs for the treatment of rheumatoid arthritis. For many people, the biological agents can slow or stop the progression of the disease, even if other medications did not help them.