The instructions to trentalu developed by the manufacturer (Indian farmatsevitcheskoy Aventis Pharma) stated that trental during pregnancy is contraindicated. However, this drug is widely used for the treatment of various circulatory disorders from occurring in this difficult for women period.
Circulatory disorders that may occur during pregnancy
Any violation of blood circulation during pregnancy may pose a risk to the fetus. In the second half of pregnancy in women can begin this complication as late toxicosis of pregnancy or preeclampsia. This condition is closely related to the stagnation of blood in the very small blood vessels - the capillaries, causing first swelling (fluid propotevaet through the walls of blood vessels), and then changes in the kidney (high blood pressure and protein in the urine), and finally by the head brain (headache, convulsions, coma).
Today, all pregnant women are under the constant supervision of an obstetrician-gynecologist of female consultation, so severe gestosis are very rare, they are usually treated at the stage of edema.
Another cause of circulatory disorders during pregnancy is fetoplacental insufficiency (FPI). It is poor circulation in the mother - placenta - fetus. Usually, it is caused by persistent spasm of blood vessels of the placenta, which is why the fetus does not receive oxygen and nutrients. Moreover, against the stagnation of blood in the blood vessels of the placenta may form thrombi. With little FPN child may be perinatal damage the nervous system and a mild developmental delay, with significant blood circulation in the placenta - severe brain damage, premature birth and stillbirth.
For what purpose trental administered during pregnancy
During pregnancy are particularly important drugs that restore normal blood circulation, one of these drugs is trental. The manufacturers of this drug is not recommended for use during pregnancy due to the fact that it is not carried out adequate clinical studies of its effects on pregnant women. However, in practice, the drug is widely used, as in this case, the potential benefits from its use exceeds the potential risk to the fetus. Of course, this drug appoint a pregnant woman (like all drugs) should be a doctor.
Trental promotes vasodilation placenta, prevents platelet adhesion (prevention of thrombus formation) and reduce the blood viscosity returns erythrocytes normal configuration, whereby they can carry more oxygen to tissues.
This action helps reduce circulatory disorders and gestosis, and fetoplacental insufficiency. Trental is usually administered in a long-acting tablets (trental - 400), which is enough to take once a day. The duration of treatment prescribed by a doctor.
With fast-paced circulatory failure in pregnant women trental can be administered intravenously.
In some cases, pregnant women are not trental appointed
Trental pills not prescribed to pregnant women with peptic ulcer disease - it irritates the stomach lining. In addition, it trental not indicated for increased bleeding or suspected internal bleeding (such as bleeding in the retina of the eye). After 33 weeks of pregnancy trental try not to prescribe, as it can lead to bleeding during delivery or cesarean section. Not appointed trental well as porphyria (inborn errors of metabolism, which is accompanied by photophobia) and hypersensitivity to trentalu and other xanthine derivatives (eg caffeine).
For intravenous trental contraindications include cardiac arrhythmias, marked atherosclerosis
Atherosclerosis - a chronic disease of the arteries
cardiac or cerebral arteries, very low blood pressure.
In most cases trental well tolerated, but there are side effects. Especially dangerous for a pregnant woman from the side effects of the cardiovascular system, such as a sharp drop in blood pressure
Blood pressure - dangerous if his swing?
, Tachycardia, cardiac arrhythmias, heart pain
Pain in the heart - always consult a doctor
Progression of angina.
Less common side effects on the central nervous system - headache, dizziness
Dizziness - if the ground is slipping from under his feet
, A constant feeling of anxiety, insomnia, sudorzhnaya readiness.
Most changes occur from the gastrointestinal tract, liver and biliary tract, which appear dry mouth, appetite disorders, atonic constipation (violation of motor activity of the intestine, which is poorly tolerated by pregnant who have and so there is a tendency to constipation), exacerbation of diseases of the gall bladder and bile ducts of the liver.
There are also visual disturbances, changes in the blood (decrease in the number of blood cells and reducing its clotting ability), redness of the skin in the form of a "tide", swelling, allergic reactions.