The active substance suprastin - Chloropyramine refers to antagonists of H1 histamine receptors. Suprastin available in tablets and in the form of solution for injection. It acts as a blocker of H1 histamine receptors and have hypnotic, sedative and antihistaminic activity and moderate peripheral anticholinergic and antispasmodic action.

Suprastin used in diseases such as allergic conjunctivitis, urticaria, vasomotor rhinitis, angioneurotic edema, hay fever, drug rash, serum sickness. Furthermore, using suprastina treat skin diseases such as eczema, contact dermatitis, atopic dermatitis, toksikodermiya.

Indications

Suprastin contraindicated in people who are allergic to components of the medication, pregnant and breastfeeding women; patients with such diagnoses as prostatic hyperplasia, angle-closure glaucoma Glaucoma - a perspective possible blindness   and respiratory failure. Children under the age of one month suprastin is only recommended when there is no safer alternative. With extreme caution should be taken suprastin people with peptic ulcer disease, and those who take MAO inhibitors and other drugs that suppress the activity of the central nervous system.

Side effects

The most common side effects are suprastin

• drowsiness,
• dizziness,
• weakness
• nausea,
• diarrhea,
• dry mouth,
• incoordination,
• gastralgia.

Overdose

In overdose suprastin children experience the following symptoms: increased anxiety Anxiety - how to distinguish normal from disease? , Hyperactivity, hallucinations, seizures, ataxia, athetosis, facial flushing, immobility of the pupils, hyperthermia, mydriasis; in severe cases, and in the absence of medical care - vascular collapse and coma. Symptoms of an overdose in adults are depression, lethargy, hyperthermia and flushing of the skin, agitation, seizures and coma. The most serious consequences occur when a significant excess of the permissible dose, and how the absence of any measures to alleviate the patient's condition. With a small overdose can try on their own to induce vomiting, take activated charcoal Activated carbon - old but indispensable   and drink plenty of water. If the dose is significantly exceeded, and especially if the patient's condition after taking the medicine has deteriorated sharply, should immediately seek emergency medical help.

Unpleasant consequences can be avoided if you take suprastin strictly in accordance with the instructions of the doctor.

Suprastin enhances the effect of the drugs, which are used for local or general anesthetics, hypnotics, sedatives, opioid analgesics. It is not compatible with ethanol, so those who take suprastin need for a time to refrain from drinking alcohol.

It does not take suprastin concurrently with tricyclic antidepressants, since they dampening effect that it has on the central nervous system. Caffeine, on the other hand, weakens the act suprastin.

Sedation

Suprastin - a drug allergen old generation, which has quite a strong sedative effect. While taking this medicine it is strongly recommended to give up control of the vehicle, as well as training activities that require human attention spans and are potentially dangerous to the health and lives of others. The simultaneous use of hypnotics or sedatives, or even non-prescription made on the basis of herbs, can lead to the oppression of the human psyche, apathy and even depression Depression - a little more than a bad mood . Before taking suprastin rate benefit ratio, which will bring you this medicine, and related risks. If possible, it is strongly recommended to take a new generation of antihistamines. Contrary to the assurances of producers, some of them still can have a sedative effect, but it is much weaker than that of suprastin.

Prednisolone has a pronounced anti-allergic properties, but allergies do not always use it. It will prednisone in anaphylactic shock, because not only has anti-allergic, but protivosokovmi properties - activates the adrenaline. In chronic allergic diseases prednisone administered in extreme cases.

As prednisolone acts on allergic processes

Prednisolone inhibits the synthesis and secretion of biologically active substances that cause allergic reactions, such as histamine. Under the effect of decreasing the number of basophils prednisolone (blood cells involved in allergic reactions) and decreasing the permeability of small blood vessels (capillaries) that reduces swelling and itching, which usually accompany allergic reaction. It reduces the number of exudate - tissue fluid, the selection of which is also characteristic of allergies. Furthermore, prednisolone suppresses excessive activity of the immune system, which is the cause of allergic reactions.

This happens due to the fact that when administered intravenously prednisolone instantly activates the stress hormone How to beat stress? Create an oasis   adrenaline, which causes a sharp narrowing of blood vessels and raising blood pressure - it saves man from anaphylactic shock.

However, prednisone has many other effects which adversely affect the patients with allergic diseases. So too strong immune suppression leads to allergic processes that joins a bacterial or fungal infection.

With prolonged use of prednisone disrupt metabolism Improves metabolism and losing weight without dieting , Contributing to increased degradation of protein and the formation of the products of its glucose metabolism. Reducing the amount of protein in the blood particularly negative impact on the development of children and adolescents: they can occur dysplasia.

A large amount of glucose in the blood can cause steroid diabetes. Under the influence of progesterone changes and fat metabolism: it produced increased amounts of fat that is deposited mainly in the upper part of the body, disrupting the proportions of the figure.

Finally, long-term use of prednisone suppresses adrenocortical function and reduces the secretion of the body's own (endogenous) glucocorticosteroid (GCS) hormones. This leads to suppression of the synthesis and secretion of pituitary gonadotropins, which affects the sexual function of patients: women disrupted menstrual cycle, and men develop impotence Impotence - a female perspective on the problem .

If any allergic diseases prednisolone

Prednisone can be administered at any allergic diseases when they occur very hard. A feature of this formulation is that during short-term treatment it has almost no side effects.

In this regard, it is administered, for example, in severe asthma when inhaled corticosteroids can not be shaped to remove bronchospasm attacks. Nominated short course of prednisolone Prednisolone - against inflammation, allergy and pain, but with complications   In this case, quickly relieves allergic reaction and restores normal breathing, which allows to return to the previous course of treatment.

As is the case with skin diseases, which are based on allergic processes such as atopic (congenital allergic) dermatitis in children and eczema in adults. These patients with very severe exacerbations when conventional treatment comes to a standstill, a short course of prednisone. Babies prednisone is prescribed less often than adults because it can cause growth retardation children. However, sometimes it is necessary to resort to such treatment.

If hay fever (allergic rhinitis and conjunctivitis caused by pollen) and perennial allergic rhinitis, prednisolone almost never used. But sometimes, when the disease is difficult and there is a threat to the transition to a different kind of allergic process (for example, asthma, which happens quite often), short courses of prednisone to help remove the threat.

Large doses of prednisone administered intravenously in anaphylactic shock, it allows you to save patient lives without any health effects.

Prednisone - is an effective tool for the treatment of allergies, which is used quite frequently, but only on prescription.

Galina Romanenko