Diprospan - it means glucocorticosteroid (GCS), which means that it combines high performance and a host of side effects, as the GCS affect all organs and systems of the human body. And this influence is not always positive.
The positive impact on the body diprospana
Diprospan available as a suspension for injection and administered as an intramuscular injection, or directly into the affected organ. It quickly and effectively reduces inflammation, allergic reactions, immunological reactions and inhibits growth of connective tissue. The composition of this drug is such that it begins to act very quickly and this effect persists up to ten days.
Diprospan needed in cases when it is necessary to remove heavy inflammatory process (eg, in the joints), accompanied by severe pain, to remove that other drugs can not be. It is used and in severe allergic diseases, uncontrolled proliferation of connective tissue and a number of other serious diseases in which only the use of corticosteroids may bring relief to the patient.
However, chronic administration of high doses diprospan can have side effects, which also can be very strong.
Side effects diprospana the central nervous system and sensory organs
Diprospan can cause headaches, dizziness, insomnia, seizures, increased pressure vnutrichepernogo (with the possible damage to the optic nerve). Often when it is used, a change of mood - from joy-high (euphoria) to the oppressed (depression), combined with increased anxiety
Anxiety - how to distinguish normal from disease?
Irritability - you try to control my temper
. In some cases developed acute psychosis with patient disorientation, delirium
Brad - not only crazy
Can violated vision due to swelling of the optic disc, sometimes forming cataracts
Cataracts - how to solve the problem completely?
, Increased intraocular pressure. There may come a sudden loss of vision when administered diprospana in the head or neck. With prolonged use dramatically increases the risk of bacterial, viral and fungal infections of the eye.
Side effects diprospana with the water-salt balance and cardiovascular
Diprospan contributes to the delay in the body of sodium and water excretion of potassium and calcium, which seriously affects the state of the cardiovascular system. The delay in the body fluid causing increased stress on the heart and swelling and insufficient blood levels of potassium and calcium leads to weakness of the heart muscle.
As a result, patients can develop chronic heart failure, persistent increase in blood pressure, cardiac arrhythmias, bradycardia (rare heart rate, sometimes - cardiac arrest). Against the backdrop of slow blood circulation developing thrombosis. In myocardial infarction a risk slow scar formation in necrosis (necrosis) of the myocardial tissue, which may lead to rupture of the myocardium.
Side effects diprospana by metabolic and endocrine
Under the influence of diprospana change all types of metabolism. Increased protein breakdown is a violation of protein metabolism, and the increased accumulation of body fat leads to its deposition in the upper half of the body and increase body weight. Changes carbohydrate metabolism: blood glucose increases and accelerates the process of fat in the liver as glycogen.
Changes in metabolism can not help but reflect on the state of the endocrine system: it may worsen for diabetes develop Cushing's syndrome (a decrease in muscle mass, increase and redistribution of subcutaneous fat, mental disorders, delayed sexual development in children), menstrual irregularities. Against the background of constant suppression of activity of the adrenal cortex occurs atrophy and decreased synthesis of their own SSC.
Side effects diprospana the part of the musculoskeletal system
Under the influence of diprospana atrophy (decrease in volume), muscle weakness. Simultaneously bone loses calcium, which leads to bone fragility and an increased propensity to fracture (osteoporosis) can develop compression (by compression) spinal fractures. There are avascular necrosis (destruction) of the heads of major long bones (femur, humerus). Due to suppression of connective tissue may be torn ligaments and tendons, resulting in instability of the joints.
Children diprospan may cause premature closure of growth zones in the bones and stunted growth.
Other side effects
Often there are erosive and ulcerative lesions of the stomach and intestinal bleeding and perforation of the walls, inflammation of the pancreas.
Disturbed wound healing, thinning skin, increases its sensitivity, tendency to irritation to skin pustular and fungal diseases, the development of stretch marks and cellulite. At the injection site may occur diprostana areas of increased or decreased pigmentation, skin atrophy, sterile abscess and pus.
Sometimes develop allergic reactions such as angioedema or anaphylactic shock.
Diprospan - is an effective drug that gives a lot of side effects.