Penkrofton - not a harmless drug

August 16, 2009

   Despite the presence of a large selection of contraceptives, abortion is still valid. Recently there were drugs that could interrupt early pregnancy without surgery. Use them yourself is not recommended, but in the hands of a specialist such drugs can be an excellent tool for termination of pregnancy. During pregnancy, actively produce female hormones that contribute to the development and preservation of the fetus in the uterus. Thus, progesterone Progesterone - norm and pathology  Progesterone - norm and pathology
   It causes changes in the uterus, readying it for implantation embryo progestational activity inhibiting uterine musculature.

Currently developed drugs that block the production of progesterone. This causes destruction of the capillaries in the endometrium, resulting in rejected mucosa. At the same time this drug increases the concentration of prostaglandins that cause muscle contraction of the uterus and expulsion of the fetus from the uterus. Active contraction of the uterus with the simultaneous opening of the cervix helps the additional administration of prostaglandins, which is held at 1, 5-2 days after administration of the drug to induce abortion.

Medical termination of pregnancy may be complicated by heavy bleeding, which is especially dangerous if a woman is at home. In addition, the fertilized egg can not move and then require surgical intervention.

 Penkrofton - not a harmless drug

What penkrofton and how it works

Penkrofton (international non-proprietary name mifepristone) - antiprogesteronnoe is a tool that promotes the binding of progesterone, that is, the process of disabling its hormonal effects on the pregnant uterus.

Used penkrofton for abortion up to 42 days. After ingestion under medical supervision miscarriage should occur within 14 days. This should be confirmed by ultrasound examination and blood hormone (human chorionic gonadotropin - hCG, which appears during pregnancy and disappears when it is interrupted).

Indications for use penkroftona a medical abortion Medication abortion: take a pill and get the problem  Medication abortion: take a pill and get the problem
   up to 6 weeks.

 Penkrofton - not a harmless drug

Contraindications for use

Penkrofton is not a harmless drug, for its reception has a number of contraindications:

  • Hypersensitivity to the drug;
  • irregular menstrual cycle, uterine fibroids, endometriosis;
  • ectopic pregnancy;
  • the scars on the uterus;
  • anemia (anemia);
  • severe diseases of internal organs (kidney or liver failure, severe diseases of the cardiovascular system, asthma and others.);
  • age 18 and after 35 years, and smoking;
  • the use of an intrauterine device or hormonal contraceptives for less than three months prior to conception.

 Penkrofton - not a harmless drug

Side effects

Among the side effects of the drug have quite serious, such as uterine bleeding. Furthermore, there may disturb the discomfort and pain in the abdomen Abdominal pain: when to sound the alarm?  Abdominal pain: when to sound the alarm?
 , Uterine infection and urinary tract infection (infection can get from the external genitalia), weakness, headache, dizziness, fever, nausea, vomiting, diarrhea.

 Penkrofton - not a harmless drug

How is medication abortion

Medical termination of pregnancy is carried out only after a thorough examination (gynecological, laboratory, ultrasound), as some diseases are contraindications for this type of intervention.

After receiving tablets penkroftona woman is under medical supervision for two hours and then goes home. A few hours later she appeared spotting Spotting - it is important to rule out pathology  Spotting - it is important to rule out pathology
 . After 48 hours at the doctor's a woman takes pills prostaglandin there for three or four hours, and then also goes home. Secretions become more abundant (like a normal menstrual period), removes the fetus from the uterus. Spotting can last up to two weeks, followed by ultrasound to check the results of medical abortion.

 Penkrofton - not a harmless drug

The can end medical abortion

Medical abortion is currently a great alternative to other forms of abortion in the early stages, as a gentle method, flows relatively painless and eliminates the possibility of infection. Its effectiveness is more than 98%.

However, there are cases of ongoing pregnancy, incomplete expulsion of the ovum, bleeding requiring surgical intervention.

Pregnancy - is a serious operation, which can always give a complication, no matter how reliable was the method used. All possible complications may provide notice in time or a doctor. That's why drugs such as penkrofton, available only by prescription.

  Galina Romanenko

Article Tags:
  • penkrofton

The pill for men: in development

January 24, 2012

 male contraceptive pill
 Contraception, as in the past, and the present is one of the issues that are addressed by scientists. But, unfortunately, almost all means of contraception are women. What is a wide range for today is represented by female contraceptives. Among them are IUDs and birth control pills and hormone injections Hormonal injections, I'm not afraid of injections  Hormonal injections, I'm not afraid of injections
 , Patches, suppositories, and even the female condom The female condom: protect anyway  The female condom: protect anyway
 . What is the share of men? Condoms and surgical sterilization. Not every man will agree even to the woman he loved to become infertile. Therefore, the researchers set out to develop a male contraceptive pill.

 The pill for men: in development

Women control pills

In comparison with male contraception pills, which are still in development, we should recall the mechanism of action of the female birth control pill. There are two groups of female contraceptive drugs - is an estrogen Estrogen - the key to bone health  Estrogen - the key to bone health
 -gestagensoderzhaschie pill and mini-pill, which include progestogen only. The action of both tablets based on inhibition of ovulation Ovulation - How to determine as accurately as possible?  Ovulation - How to determine as accurately as possible?
   (egg maturation and release) through hormones coming from outside. Hormone pills woman must take each day. Restoration of fertility happens after about three months after the end of hormonal contraceptives.

 The pill for men: in development

From the history of development of male contraceptive pill

It seems that everyone is engaged in the creation of contraceptive pills for men. In many European countries, and also in America and China conducted experiments on the production of these tablets:

  • Israel

It is known that Israeli researchers have created the first male contraceptive pill. Its action is based not on the effect of hormones, but on blocking a protein that is part of the sperm. Scientists are inclined to think that the contraceptive effect when taking this pill is 100% (as in the admission of female contraceptives). This pill should be taken only once every three months, which is a huge advantage to female contraceptives. Israeli scientists have argued that blocking the protein in the sperm makes them "incompetent." In addition, such tablets do not possess pronounced side effects.

  • Germany

The German pharmaceutical company Schering and the Dutch company Akzo Nobel joined forces and began to develop male contraceptive pill. They promise to provide similar drugs on the market in five to seven years. Difficulties develop male contraceptive pills, as claimed, these drug companies are developing in a large male sperm (in contrast to women, the body of which once a month matures one, at least two or three ova).

The structure of the developed experimental model - tablet includes a synthetic hormone action is based on suppressing sperm production, and as an additional effect of blocking properties of testosterone.

  • America

Towards a contraceptive pill for men US researchers have come by chance. Colleagues dermatologists have tried to develop a new tool for the treatment of skin and inflammatory diseases, but abandoned the experiments on an experimental drug because of its toxicity for men (influence on the testes). After learning of the drug, the researchers came to the conclusion that it can be successfully used to create a male pill. The essence of the action of the tool is based on the reduction or even the complete absence of vitamin A. Vitamin A deficiency When a man is reduced ability to fertilize.

  • China

Male contraceptive pill, developed in China contains heavy doses of a hormone similar to testosterone by the action. Another embodiment of such tablets includes a plurality of testosterone and estradiol (female sex hormone). In experimental studies, these drugs have shown high efficiency. The only drawback is the bottom pills System the impact of testosterone on the body, which leads to increased blood cholesterol levels and the development of cancer.

Anna Sozinova

Article Tags:
  • birth control pills