Diferelin - a drug used to treat prostate cancer and sometimes - endometriosis Endometriosis - a serious problem with serious consequences , Female infertility Female infertility - whether all known to science?   and uterine fibroids. Most often it is used, that slow the spread of prostate cancer and its metastasis in the later stages of the disease.

The action of the drug

In most cases of prostate cancer requires testosterone, a hormone secreted by the testes and pancreas Diabetes and pancreas - the things you need to know . Testosterone, in turn, stimulates the pituitary gland produces luteinizing hormone. Diferelin reduces the production of luteinizing hormone, which leads to a decrease in testosterone levels. This may slightly reduce the tumor or slow its growth. Due to the action Diferelin on the pituitary gland, it, although much less frequently used in the treatment of certain serious diseases in women.

How to take Diferelin

Diferelin administered intramuscularly or subcutaneously. Depending on the concentration of active substances in the solution and the severity of the disease, the drug is administered every month or every three months. After the injection, the patient may feel some discomfort at the location where the drug was administered. In some cases, before making an injection, is administered a low dose of a local anesthetic.

The duration of treatment depends on the patient's condition. The course of treatment may last from several months to several years - as long as Diferelin helps control cancer.

Side effects

Each patient responds to drugs individually. The complete absence of side effects while taking Diferelin unlikely as it is powerful medicine that has an influence on various systems of the body.

Most often in patients taking Diferelin, you experience the following side effects:

• A temporary increase of the tumor. This phenomenon is sometimes called a flash tumor. In the first few days after the first injection Diferelin increases testosterone levels, and swelling temporarily increased. The patient in this case may be amplified body aches, and sometimes there is difficulty urinating. This is normal and doctors often warn patients about this side effect. After a few weeks the patient's condition improves. If not, talk about it with your doctor.
• Hot flashes and sweating often occur in patients undergoing treatment Diferelin. If they are very anxious, ask your doctor to recommend a medication that will help to deal with it. Often these symptoms are better if the patient restricts the use of tea, coffee, nicotine and alcohol.
• Decreased libido and erectile dysfunction. Unfortunately, during treatment with this little can be done, but the libido and potency is usually restored after the end of therapy.
• Soreness and / or breast augmentation. Some men during treatment Diferelin developing gynecomastia Gynecomastia - known since ancient times   - Increases and becomes unusually painful breasts.
• Nausea, vomiting and diarrhea - a relatively rare side effects Diferelin. In most patients, they pass quickly; If these symptoms persist for a week or more, talk to your doctor.
• Osteoporosis. The risk of osteoporosis increases with long reception Diferelin. Usually, the doctor prescribes to patients regular surveys to monitor the changes in bone tissue.

Furthermore, during reception Diferelin increased risk of diabetes, heart disease and certain other diseases. However, the benefit of treatment in most cases considerably exceeds the harm from side effects.

What are adhesions, their types and causes of formation

Adhesions (adhesions, Mooring) - a connective tissue adhesions between adjacent organs or surfaces. Adhesions are divided into congenital and acquired. Congenital adhesions occur in congenital malformations of an organ. Acquired develop adhesions after inflammation or bleeding in the internal cavity of the body: not resolved inflammatory fluid or blood gradually thickens and grows connective tissue (organized). Initially loose connective tissue and adhesions easy to disunite, but over time it becomes strong and may even be impregnated with calcium salts such stiff spikes divide is very difficult. Over time, the spikes appear blood vessels and nerves.

Adhesions can be single or multiple, sometimes envelop the entire body or bodies, causing their displacement and deformation. Abundant salt deposits The deposition of salts - a disease of old men?   calcium in the outer shell after the inflammation of the heart (pericarditis) leads to the formation of calcareous shell - the so-called stone heart. The organization of the inflammatory fluid in the pleural cavity (two sheets of pleura cover the lungs, forming together the pleural cavity) often found multiple dense adhesions, which in some cases contain a fatty tissue that act as shock absorption. When inflammation of the peritoneum (it covers the inside of the abdominal cavity) spread the adhesive process is rare, however, adhesions in the abdominal cavity may lead to adhesive disease.

Restricting the mobility of internal organs, pain and mechanical obstruction (e.g., intestine) is often require surgical intervention. In some cases, small and not fully organized adhesions resolve after physical therapy.

Adhesive disease

Adhesive disease - is the formation of abdominal adhesions in a number of diseases after injuries and operations. The most common adhesive disease develops after an inflammation of the appendix and its removal (appendectomy). Adhesions can also develop after surgery for intestinal obstruction, gynecological and urological surgery.

In the formation of adhesions in the abdominal cavity leading place occupies an inflammation of the peritoneum. But they can appear after mechanical damage to the peritoneum (injury), it impacts on any chemical substances (e.g., burn iodine). When abdominal trauma important long paresis (immobility) of the intestine, which creates favorable conditions for adhesions bowel loops due to their prolonged contact with each other.

In some cases, the formation of adhesions becomes progressive course, the cause of which is not quite set, but they are definitely linked to the degree of spread of the inflammatory process. In these cases, the deformation occurs intestines, impaired motor activity, and its passage of intestinal contents.

Signs of adhesive disease

Adhesive disease can occur in different ways. Sometimes it begins as a sudden or gradually rising twinge, enhanced motility (movement) of the intestine, followed by vomiting and a rise in temperature. Quickly showing signs of intestinal obstruction Ileus - the reasons may be different Sharply deteriorating general condition (dehydration occur due to repeated vomiting, weakness, sudden drop in blood pressure).

There is also a long-term course of the disease with aching abdominal pain, discomfort, constipation Constipation - Watch out for food , Violation of the general state of health and periodic bouts of acute intestinal obstruction.

Diagnosis and treatment of adhesive disease

The diagnosis of adhesive disease put on the basis of its typical symptoms, and after x-ray examinations of the abdominal cavity.

The treatment of adhesive disease Adhesive disease: almost inevitable after surgery   It depends on its manifestations. Nevertheless, conservative therapy should be leading, and surgery should be performed only when the threat to the life of the patient. The most frequently used thermal treatments: mud, paraffin and ozocerite baths, flat cakes made of mud, electrophoresis with drugs (painkillers, absorbable) and so on.

During an acute attack, are not permitted by a conservative measures within one to two hours, surgical treatment (elimination of obstacles to the movement of feces), with repeated attacks - a surgical treatment to prevent acute attacks.