Hypothyroidism is called primary when the process that caused the failure of the thyroid gland, begins directly in its tissue. This is due to injury, congenital abnormal development, inflammatory or allergic process, including the allergy to the body's own tissues, the destruction of the thyroid gland by exposure to radiation, surgery on the thyroid gland.
What causes primary hypothyroidism
The cause of primary hypothyroidism, arose immediately after birth or within the first two years, is a congenital disorder of the thyroid gland, the presence of hypothyroidism in pregnant women inherited structural features of the thyroid gland, the reception of a pregnant woman drugs that suppress thyroid function (eg merkazolila, used to treat elevated thyroid function).
Primary hypothyroidism may result from the development of the inflammatory process in the thyroid gland - thyroiditis. This inflamed tissue is gradually replaced by connective tissue, which can not produce hormones.
Congenital thyroid atrophy involves a complete absence or a sharp decrease in the volume of its fabrics. If congenital hypothyroidism
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caused by genetic processes, the child gradually formed a nodular goiter.
Primary hypothyroidism can occur due to violations of release of thyroid hormone or due to the reduction of tissue sensitivity to these hormones. In adults, primary hypothyroidism is formed more often in women after forty years. This is mainly due to the autoimmune processes occurring in the thyroid gland, when inflammatory process is the result of an allergy to their own thyroid tissue. Autoimmune process became increasingly occur in young people, including children.
Signs of primary hypothyroidism
In primary hypothyroidism in patients appear lethargy, daytime sleepiness and sleep disorders
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night, the inability to warm up (patients constantly freezing), impaired memory, slow speech and movement, decreased ability to work, pain in joints and muscles, puffy and pasty face, hands and feet. Nails become brittle, streaked longitudinal and transverse stripes. Hair fall out, make thin, whipped at the ends. Sometimes hair loss causes the hair become rare in other cases, hair loss is alopecia.
By decreasing the amount of thyroid hormones
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often increases body weight, there are pains that arise from the infringement of spinal nerves, including those caused by herniated intervertebral.
The lack of hormones can cause menstrual disorders (too heavy or, on the contrary, is too brief and scanty menstruation, the complete absence of menstruation, hoarseness due to swelling of the vocal cords, hearing loss). The voice may be hoarse.
If the primary hypothyroidism is far gone, the appearance of the patient has the characteristic form: swollen face (especially pronounced swelling in the lower eyelids), pale yellowish color, fixed (broken facial expression) features appear larger. Language swells, grows in size, sometimes do not fit in the mouth on the side of its surfaces appear crisp prints posterior teeth. The skin is dry to the touch, cold (impaired thermoregulation), the patients can not tolerate the cold.
There are muscle pain, reduced muscle strength, fatigue, and sometimes - jerking of muscles. The volume of the muscles may increase due to the proliferation of these connective tissue, muscles made tight, stiff.
Changes in bone occur mostly in children, in adults, they are rare, they sometimes in advanced hypothyroidism there is bone loss due to calcium loss (osteoporosis). There may be a violation of metabolic processes in the joints (osteoarthritis), pain in joints
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.
The lack of thyroid hormone causes a disturbance on the part of the blood circulation: slow heart rate, pain in the heart, sometimes - irregular heartbeat, increased blood pressure with an increase mainly lower, diastolic pressure.
Due to the swelling of the mucous membranes of the respiratory tract occur constant bronchitis and pneumonia. Often these diseases occur continuously and without raising the temperature. He suffers from the entire gastrointestinal tract, especially characterized by constipation and stagnation of bile in the biliary tract.
In most cases, there are various mental disorders and intellectual impairment.
Serious complication of primary hypothyroidism may be hypothyroid coma, which occurs when the patient did not receive long-term treatment. In this case the confusion comes first, followed by a deep stable of its loss, which is accompanied by a decrease in body temperature.
Helping patients with primary hypothyroidism can only replacement thyroid hormone therapy.
Galina Romanenko