Geptral - it hepatoprotector (drug, a beneficial effect on the liver function) with antidepressant activity. It is widely used both in various diseases of the liver to prevent their progression and in psychiatry, where used to display the status of the patient's depression Depression - a little more than a bad mood .

Features geptrala injection

Manufacturer geptrala pharmaceutical company Abbott (USA) has developed detailed instructions for use of the drug, but it always assigns the doctor, he also picked individually daily dosage and duration of treatment.

Geptral injection actively influences the condition of the liver cells (hepatocytes). Basically it regulates deducing therefrom the bile acids and other substances are removed from the body in the bile. Bile acids are removed from the cells through the membrane by means of special transport systems.

If you violate state and hepatocyte membrane under the action of toxins of various origins and disrupted transport systems. This leads to accumulation within the hepatocyte bile acids that destroy them, and then place hepatocytes grows connective tissue. Geptral suspend this process, it restores normal cell membranes, transport through her bile acids. Damaged cells under the influence of geptrala restored, and the process of cell proliferation of the connective tissue is suppressed, which contributes to the stabilization of the liver with cirrhosis of any origin.

Similarly Heptral protects liver cells from the action of any toxins is formed within the body (eg, free radicals), and received from the outside (alcohol, drugs, hepatotoxic drugs).

It was also established that the active substance geptrala ademetionine can penetrate the blood-brain barrier, that is exposed from the blood into the brain tissue. Here he is actively involved in the biochemical processes and restores normal neurons. This improves the conductivity of nerve impulses, activates the activity of the entire central nervous system and the patient comes out of the doldrums.

Which diseases Heptral administered by injection

The main indications for the purpose geptrala by injection are acute and chronic diseases of the liver and biliary tract. Geptral help when exposed to any damaging liver tissue factor - viruses and toxins, bile acids, free radicals, toxic agents (alcohol, drugs, etc.). In addition, Heptral prescribed for stagnation of bile in the biliary tract - in the bile ducts and gall bladder, but in the absence of this system rocks.

Geptral often prescribed for depression and, especially, in the case when patients revealed resistance (immunity) to other antidepressants such as amitriptyline.

As prescribed Heptral

In order that the treatment was effective, geptral first administered as intramuscular or intravenous injection, which are then replaced with the tablets. Powder for injection in vials diluted enclosed solvent immediately before injection, the medication remainder can not be stored. Introduction of the solution into the vein to be very slow. Geptral not be diluted with alkaline solutions or solutions, which include calcium.

This is an average of 400-800 mg exceed this dose is not recommended. The course of treatment for injection in liver disease is two weeks, depression - three weeks. Thereafter, it is recommended to go to the reception geptrala inside a pill of 800 - 1200 mg per day. Duration of treatment is determined by a doctor, but it can not be short-lived, on average, it is recommended to take Heptral from two weeks to two months.

Side effects and contraindications

Adverse effects in geptrala injecting slightly more than the tableted dosage form:

• the part of the digestive system - dry mouth, nausea, vomiting, abdominal pain Abdominal pain: Types and Symptoms Diarrhea; sometimes develop inflammation of the esophagus, abdominal swelling, bleeding from the stomach or intestines, liver colic;
• on the part of the brain - insomnia, dizziness, headache, sensory disturbances, confusion;
• on the part of the musculoskeletal system - pain in muscles and joints, cramps;
• on the part of the urinary tract - the development of infectious and inflammatory processes;
• of the skin - increased sweating, itching, skin rash;
• Local reactions - sometimes at the injection site irritation and even death (necrosis) of the skin, inflammation of the veins (phlebitis);
• sometimes on background geptrala injections may rise high fever, weakness, swelling, allergic reactions.

Contraindications Heptral Geptral - protection and support to the liver and not only   in case of hypersensitivity to it of the patient, in the first and second trimesters of pregnancy, breast- Breastfeeding - a personal choice   chest and under the age of 18 years.

Galina Romanenko

Duspatalin refers to myotropic spazmolititikam. This means that it has a direct relaxing effect on the smooth muscles of the digestive system. A feature of this product are high efficiency and lack of effect on normal motility of the gastrointestinal tract.

What myotropic antispasmodics and how they work

Antispasmodics - drugs, relieves spasms of smooth muscle. All muscles in the human body is divided into striated or skeletal (it carries traffic) and smooth, which is located in the internal organs and blood vessel walls. Smooth muscle contraction and contributes to the expansion of the lumen of blood vessels, performs peristalsis and promotion of his stool, promotes the timely removal of bile and pancreatic secretions Diabetes and pancreas - the things you need to know   in the intestine and so on.

Spasms of smooth muscles of the digestive organs accompanied usually pain. Drugs that are called antispasmodics, relieve spasm and pain that improves blood circulation in the concerned bodies and restore its function.

Myotropic called antispasmodics, which have a direct effect on the smooth muscles. The first was myotropic antispasmodics papaverine, which is in the middle of the 19th century isolated from the opium poppy. In the future, some changes in the chemical formula of papaverine Papaverine - for pain caused by spasms of smooth muscles   possible to increase the efficiency of its action, a new drug called drotaverine (pharmaceutical industry produces mainly called no-spa).

Today, there are more effective myotropic antispasmodics, which include, for example, mebeverin (Duspatalin).

What is the difference Duspatalin of papaverine and shpy

Duspatalin (active substance - mebeverin) refers to myotropic spazmolotikam last generation that are highly efficient in removing the spastic increased activity of smooth muscles of the gastrointestinal tract. This Duspatalin Unlike papaverine and shpy not suppress the motor activity of the digestive system completely and do not cause atony: is maintained normal motility of the gastrointestinal tract, biliary tract and pancreatic ducts, allowing to maintain the proper functioning of the gastrointestinal tract. It also has fewer side effects than papaverine Nospanum.

Which diseases are taking Duspatalin

Duspatalin prescribed for such diseases of the stomach and duodenum, as chronic gastritis and peptic ulcer disease. Removing the spasms of smooth muscles not only reduce pain, but also improve blood circulation in the walls of the stomach and intestines, which in turn helps to reduce inflammation and the rapid completion of relapse.

In diseases of the intestine (irritable bowel, chronic colitis) and goiter, which may be accompanied by bouts of colic, Duspatalin is the drug of choice because it does not inhibit intestinal motility and does not cause constipation.

Duspatalin widely used in diseases of the biliary tract and pancreas: removing spasms excretory ducts of these organs, it does not suppress their natural peristalsis, and thus prevents the stagnation of bile and pancreatic juice.

Contraindications and side effects

Duspatalin has very few contraindications. This hypersensitivity to the drug, age 18 and breast-feeding Breastfeeding - a personal choice   feeding. The last two contraindications related to the lack of clinical trials of the drug in these group of patients.

With caution and only for health Duspatalin used to treat pregnant women as well as the action of the drug in the pregnant woman and the fetus has been insufficiently studied.

Duspatalin - a non-toxic drug, it is usually well tolerated. The exceptions are patients who Duspatalin cause allergic reactions. Allergy to Duspatalin proceeds in the form of a skin rash, sometimes itchy, including in the form of urticaria and angioedema Prevention and treatment of edema - it is important to understand the root cause . If you suspect an allergy Duspatalin overturned.

Duspatalin no effect on the concentration and coordination of movements, so during his reception can drive a car and engage in any other activities that require attention.

Duspatalin - a modern and effective non-toxic antispasmodic, which helps to relieve spasms and pain in the digestive system.

Galina Romanenko