Steatosis - a disorder in which the liver cells accumulate excessive amounts of fat. This disease is very common and, although in most cases it does not lead to serious diseases of the liver, sometimes the accumulation of fat in the tissues of the body causes severe and even life-threatening diseases. Therefore, treatment of fatty liver is so important and necessary.

How to treat steatosis

• Weight Loss

Most of the cases of FH is associated with overweight and obesity, so weight loss is an important condition for the successful treatment of this disorder. To achieve a significant improvement, it is necessary to reduce the weight, at least 10%. Losing weight reduces the likelihood of developing liver cirrhosis and other complications hepatosis. Typically, patients are recommended to lose weight by approximately 0.5-1 kg per week.

Since half a kilogram of adipose tissue contains about 3,500 calories to achieve this result, you should consume daily, a minimum of 500 calories less than you spend. At the same time we must remember that too rapid weight loss is potentially dangerous to health.

• Avoiding alcohol

Treatment of liver steatosis involves abstinence from alcoholic beverages if the disease was caused by alcohol (alcoholic fatty liver). That is entirely abandon the alcohol does not necessarily - you just stick to the recommended standards of consumption of alcoholic beverages. However, the alcoholic fatty liver is most common in people with alcohol dependence Alcohol addiction - for no reason, no reason not arise And for them it is often easier not to drink than to drink a little. If the patient stops drinking, two weeks liver starts to remove excess fat and the risk of developing cirrhosis of the liver is gradually reduced.

• Food

Traditionally, the treatment of fatty liver does not recommend any special dietary restrictions. In recent years, however, many experts have noticed that the treatment affects not only how many calories a patient consumes, and which nutrients are included (or not included) in his diet.

For example, in patients with alcoholic liver hepatosis often it is deficient in certain vitamins and minerals, so it is important for them to adjust the diet so as to compensate for the lack of nutrients. In addition, recently there have been reports indicating that the consumption of large amounts of sugar increases the risk of fatty liver, and limit sugar consumption contributes to more efficient and rapid treatment of this disorder.

• Physical exercise

Physical activity in fatty hepatosis useful not only because they contribute to weight reduction. Increased muscle increases sensitivity to insulin The principles of action of insulin - the science of saving lives   - It is important for patients with type 2 diabetes, which is known to be one of the factors that increase the risk of FH. In addition, regular stress contribute to a more rapid reduction in the level of harmful cholesterol in the blood.

The study, which was attended by 800 patients with FH, showed that regular intense load significantly reduce the risk of scar tissue in the liver.

• Drug treatment of hepatic steatosis

Special preparations for the treatment of this disease do not yet exist, and basic therapy are weight loss, nutrition Proper nutrition - the basic precepts of healthy food   and abstinence from alcohol.

However, according to several studies, some drugs in fatty liver gepatoze can facilitate the patient's condition and prevent complications. For example, pioglitazone can be used to steatohepatitis, develops on the background of fatty liver. However, it is unclear how effective and safe the drug is in the long term.

It is assumed that the intake of vitamin E and omega-3 can accelerate the recovery of patients with FH and reduce the risk of complications, but the researchers believe is premature to recommend widespread use of these compounds in the treatment of this disease.

If the development of fatty liver in a patient associated with diabetes, it is important that this disease was controlled - it is necessary to regularly take anti-diabetic drugs. Sometimes it is also required to take medications that reduce blood cholesterol.

• Experimental drugs

Currently, studies are (yet - only on animals), during which studied the possibility of use in the treatment of fatty liver drugs such as N-acetylcysteine ​​and blockers of cannabinoid receptors.

Forecast

In most cases, weight loss, refraining from excessive use of alcohol or adequate treatment of diabetes is sufficient to state of the liver in a patient FH improved. Often, the fat content in its cells is completely normal, and if the patient will continue to lead a healthy life, he has a chance to never do not run into any liver disease.

This disease can develop in spite of early treatment, and why this happens is unknown. But the most common cause of severe disturbances in patients with FH (especially - with non-alcoholic form of the disorder) is cardiovascular disease. Therefore, doctors recommend that people diagnosed with steatosis, not to concentrate exclusively on the problems of the liver, and to change the way of life in general, to reduce the likelihood of developing heart disease Heart disease and heart attacks: that every woman should know .

Active ingredient Motilium Domperidone was first synthesized in the mid-seventies of the last century in the Belgian pharmaceutical company Janssen Pharmaceutica. For over thirty years, this drug is used in the treatment of various diseases of the digestive system, as well as to relieve the nausea and vomiting of any origin (except for vomiting in motion sickness).

Based on what action motilium

Motilium (domperidone INN) is a dopamine receptor antagonist. Dopamine - a neurotransmitter, by which the nerve cells in the brain transmit nerve impulses that signal trouble in the gastrointestinal tract.

Dopamine transmits to the vomiting center about trouble in the gastrointestinal tract, causing nausea and vomiting, as well as inhibits the tone and motor activity of smooth muscles of the gastrointestinal tract. All drugs - dopamine receptor antagonists (including motilium) block its transmission to the receptors, thus their effect is the opposite effect of dopamine: removal of nausea and vomiting, increased tone and motor activity (motility) of the upper gastrointestinal tract.

Under the action of dopamine are nausea and vomiting from any source other than the vestibular, ie nausea and vomiting, which develop during rocking. Accelerated gastric emptying, promoting it to the duodenum, is prevented from flowing back into the acidic contents of the stomach into the esophagus, and the irritation of its walls, that is, the development of esophagitis (inflammation of the walls of the esophagus).

It is believed that motilium can not overcome the blood-brain barrier and enter the central nervous system (CNS), but this does not always happen. If a certain amount of Motilium nevertheless penetrates into the brain, it may develop headaches, dizziness Dizziness - if the ground is slipping from under his feet   and extrapyramidal disorders. Extrapyramidal system regulates the activity of skeletal muscle: posture, gait, coordination and so on. When extrapyramidal disorders may experience involuntary movements (hyperkinesis, tics) or the absence of any movement (hypokinesia), disturbed gait, and so on. But such violations are rare.

Who can take motilium

Motilium tablets, coated tablets, prescription according to take at diseases of esophagus, stomach and duodenum, the delay associated with movement of food through the digestive tract and its flowing from the stomach into the esophagus (gastroesophageal reflux). If reflux of acidic stomach contents into the esophagus and thrown irritating its walls, causing inflammation (reflux esophagitis).

Such a condition may arise in case of violation of motor activity of smooth muscles of the stomach, as well as the failure of the lower sphincter (a circular sphincter) of the esophagus. Gastroesophageal reflux can cause significant changes in the walls of the esophagus and attaching a bacterial infection. Motilium contributes to timely evacuation of stomach contents and prevents the development of gastro-esophageal reflux disease.

Motilium a lingual (for sucking in the mouth), tablets applies to non-prescription drugs. It can be taken for nausea, vomiting, heartburn, bloating, constipation. But if this condition persists, consult a doctor and get tested.

Assign motilium as during some diagnostic tests, such as X-ray gastrointestinal tract, which is accompanied by ingestion of barium.

Contraindications

Motilium should not be taken with the patient hypersensitivity to its components, bleeding from the stomach or intestines, intestinal obstruction, perforation of the walls of the gastrointestinal tract, taking certain medications (fluconazole, erythromycin Erythromycin - if you are allergic to penicillin , Ketoconazole), elevated levels of the pituitary hormone prolactin Prolactin - effect on the body is not fully known , Feeding baby Breastfeeding - a personal choice   feeding.

With caution and only in the case of the vital necessity of prescription Motilium is used during pregnancy, the liver and kidney.

Do Motilium side effects? Rarely, but there are (mainly the drug is well tolerated). Before the drug can occur phenomena such as headaches, dizziness, extrapyramidal disorder, nipple discharge, and menstrual disorders in women, breast enlargement in men, intestinal colic. Occasionally develop allergic reactions.

Galina Romanenko