Reglan - a drug that can suppress or reduce nausea and vomiting of any origin, as acting on the vomiting center in the brain. Because of these properties Cerucalum found wide application in the treatment of various diseases.

How does tserukal

Reglan (INN - metoclopramide) issued the Croatian pharmaceutical company Pliva tablets and oral solution in vials for intramuscular and intravenous administration.

Reglan belongs to the group of centrally acting antiemetic drugs that block dopamine receptors. Dopamine - a neurotransmitter, by which at the attachment of nerve cells (synapses) are transmitted nerve impulses. Nerve cells that are sensitive to dopamine (dopamine receptors) located in the lower part of the stomach and duodenum, through their information in the form of nerve impulses transmitted to the vomiting center located in the brain. Reglan blocks dopamine receptors and can not transmit information about the condition of the gastrointestinal tract in the center, so the center and not respond with the relaxation of smooth muscle, causing unpleasant symptoms such as nausea and vomiting.

Reglan also contributes to the rapid emptying of the stomach by increasing the activity of the smooth muscles of the stomach and upper duodenum. It is able to reduce the abandonment of stomach contents into the esophagus (reflux), thereby preventing the development of inflammation in the esophagus from irritation of the mucous membrane of its acidic stomach contents (reflux esophagitis). Overall Reglan has a positive effect on the tone and motor activity of the upper gastrointestinal tract. Reglan can stimulate the secretion of several hormones and adrenal pituitary gland, resulting in short delay in the body fluid. After receiving Cerucalum are nausea and hiccup.

Reglan enters the bloodstream, there can pass into the central nervous system (overcomes the blood-brain barrier), and the placenta to the fetus (overcomes the placenta) and may be isolated from human milk. Cerucalum decomposed in the liver and then excreted through the kidneys.

Who appointed tserukal

Reglan is prescribed:

• when hiccups, nausea and vomiting of any origin; it does not help only when changes in the vestibular system;
• while reducing motor activity of smooth muscle of gastro-intestinal tract, bile duct and gall bladder;
• when reflux esophagitis - inflammation of the wall of the esophagus caused by constant throwing of stomach contents into the esophagus;
• spasm in the transition area of ​​the stomach into the duodenum;
• in paresis smooth muscles of the stomach, which may occur in diabetes;
• during X-ray examinations of the digestive system to enhance motor activity and rapid passage of contrast material through the intestines;
• during duodenal intubation - to accelerate gastric emptying.

This is not necessary to appoint tserukal

Contraindications for the purpose Cerucalum are bleeding from the gastrointestinal tract, intestinal obstruction, perforation of the wall of the stomach or intestines, some hormone producing tumor of the pituitary and adrenal glands, severe movement disorders, epilepsy, glaucoma Glaucoma - a perspective possible blindness   (increased intraocular pressure), hypersensitivity to the drug, the simultaneous use of drugs that suppress the increased motor activity of smooth muscles of internal organs.

Reglan is also contraindicated in the first 12 weeks of pregnancy, with caution, and only on prescription can be applied in the second and third trimesters of pregnancy. Do not use Reglan Reglan: help against nausea   during breast Breastfeeding - a personal choice   breast and infants up to two years.

Side effect

Reglan may cause the following side effects:

• from the brain and spinal cord - headache, dizziness, anxiety, fear, depression, lethargy, drowsiness, tinnitus, involuntary jerking and spasms of muscles of the face and upper body, speech, and some other movement disorders;
• from the blood - decrease in the number of granulocytes (granular white blood cells), which causes low immunity;
• on the part of the cardiovascular system - tachycardia Tachycardia - the body to the limit? , Increase or decrease in blood pressure;
• the part of the digestive system - constipation, diarrhea, dry mouth;
• on the part of the endocrine system - increased secretion of pituitary hormone prolactin can cause irregular menstruation and breast milk excretion in nulliparous women and breast enlargement in men.

Overdose Cerucalum all causes increased side effects.

Reglan - a drug that has to appoint a doctor.

Galina Romanenko

What helps heartburn, one of the most unpleasant sensations? There are many ways to relieve heartburn. But if heartburn occurs frequently, then remove it by yourself there's no point - so you can only make the problem worse. That's right - to seek help from a doctor, a gastroenterologist, and find out the cause of this phenomenon.

What is heartburn and why it occurs

Heartburn is an uncomfortable burning sensation in the sternum. Develops heartburn due to acid gastric juice entering the esophagus. Heartburn can sometimes occur in healthy people with overeating, drinking large amounts of fatty fried foods. However, after the removal of such heartburn rarely repeated.

Constant heartburn can be a sign of increased acidity of gastric juice and throwing it (reflux) into the esophagus. Such a state is dangerous in that the walls of the esophagus become inflamed and irritated - develop chronic esophagitis. Today, this disease is called gastroesophageal reflux disease (GERD). GERD may be complicated by ulcerative process and even perforation of the esophagus wall. Therefore, the disease should be promptly evaluated and treated.

How to treat heartburn

Heartburn Treatment - a treatment of the underlying disease that caused it. It includes proper nutrition Proper nutrition - the basic precepts of healthy food , Drugs, reducing the acidity of gastric juice, mineral water drinking and so on.

Remove heartburn can attack in different ways, with the help of food: for example, if you drink a glass of milk, heartburn pass. If heartburn is often worried, should be excluded from the diet foods that promote secretion of gastric juice (rich broth, fatty, fried spicy food, sweets, baking, alcohol, strong tea and coffee), sour fruit and berries.

Help relieve heartburn and weakly alkaline mineral water - Slavyanovskaya, Smirnoff, Essentuki mineral water 17. What to drink with heartburn, it is best to tell the doctor after Behavior Survey. This folk remedy, like soda, it is better not to apply as flatulence will adversely affect the walls of the stomach and esophagus.

What medicines can help with heartburn

Today issued a number of medications that can relieve heartburn. First of all, it antacids that neutralize the hydrochloric acid that is operating on the same principle as that of soda. But modern antacids are soft, do not cause increased gas and do not irritate the walls of the gastrointestinal tract. Receiving drugs such as Almagel, Maalox, Aluminium phosphate gel Fosfalyugel - a cure for heartburn, belching and stomach pains   quickly relieves heartburn, but long on their own, these drugs can not be used.

Newer drugs to relieve heartburn - a proton pump inhibitors such as omeprazole Omeprazole - ulcer help . These drugs block the secretion of hydrochloric acid for a sufficiently long period of time - for preventing heartburn omeprazole sufficiently taken twice per day.

In case of violation of motor activity of the gastrointestinal tract at a constant heartburn doctor may prescribe drugs from the group prokinetic (motilium, tserukl and so on). They enhance the motility of the gastrointestinal tract and the food is rapidly cleared from the stomach into the intestine, which prevents its abandonment the esophagus.

Reduce gastric acidity and heartburn may also suppress some vitamins. For example, the docks, which include vitamins B5 and vitamin U. Both vitamin inhibit the secretion of gastric juice.

Folk remedies for heartburn

Traditional medicine has a whole arsenal of heartburn:

• Juice of raw potato - you can drink 2-3 tablespoons; but you can just chew on raw potatoes;
• cabbage juice - also perfectly removes heartburn; take it for a quarter or half a cup 3 times a day for half an hour before meals;
• celery juice - it is enough to take one tablespoon;
• heartburn can be removed in the following extract: take 2 teaspoons of herb mint Mint and its useful properties: aromatic freshness   and sage, 1 teaspoon of chamomile flowers, brew a liter of boiling water and take half a glass of heartburn or 3 times a day for half an hour before meals;
• with a strong heartburn can take an infusion of the following charges: a teaspoon of chamomile flowers on the dining false marigold flowers and leaves his mother and stepmother; All mix, take a tablespoon of the collection, pour a glass of boiling water, drain, squeeze and take a tablespoon 3-4 times a day before meals for 10 days.

All of these tools can be used for infrequent heartburn associated with eating disorders. If heartburn is often repeated, should see a doctor to complete the survey, and only then take the medication that the doctor prescribe.

Galina Romanenko