Trental - a drug that is usually well tolerated. But it has a number of contraindications and side effects, which should be kept in mind when assigning the drug. It is also possible overdose, which are difficult tolerated. In this regard, I trental available in pharmacies by prescription only.

How does trental

Trental affects the blood vessels expanding their clearance. In addition, it prevents agglutination (aggregation) of platelets, thus preventing blood clots. Trental also helps to restore the normal shape of red blood cells, and they start to carry more oxygen to the cells of the tissues.

Such a beneficial effect on blood circulation allows you to assign trental for many diseases that are accompanied by circulatory disorders. First of all, it is a disease associated with vascular changes in the background of atherosclerosis: cerebrovascular accident, ischemic heart disease, atherosclerotic changes in vessels of the extremities. Circulatory disorders can also cause diabetes mellitus, autoimmune diseases, congenital vascular disorders, vascular innervation.

Trental can produce side effects that are manifested in a sharp decrease in blood pressure, tachycardia, pain in the heart, insomnia, anxiety appearance Anxiety - how to distinguish normal from disease?   and fears, headaches, dizziness and convulsions. On the part of the gastrointestinal tract may be dry mouth, loss of appetite, abdominal pain Abdominal pain: Types and Symptoms . Possible exacerbation of chronic diseases of biliary tract and gall bladder, and on their background - abnormal liver function.

Contraindications

Contraindications for the purpose trental is acute myocardial infarction, as the dramatic expansion of the coronary (carry blood to the heart muscle) vessels can be dangerous in this disease. Dangerous drop in blood pressure, which can cause trental. Do not use Trental if atherosclerosis of the coronary vessels.

Do not use Trental if blood clotting, bleeding, including internal hemorrhage (brain haemorrhage, retinal), porphyria (congenital disorders sharing, accompanied by photophobia), and in case of hypersensitivity to the components of this drug.

If it is necessary to appoint a woman to the drug while feeding the baby Breastfeeding - a personal choice   feeding, it is recommended to discontinue treatment time as trental excreted in breast milk.

Harder appointment trental pregnant women. The instructions to the drug clearly states that the drug is contraindicated in pregnancy, as adequate clinical trials on the effects of it on pregnant women and the fetus was conducted. However, in practice Trentalum widely used during circulatory disorders during pregnancy, in particular when gestosis and circulatory disorders in the blood vessels of the placenta.

Intravenous infusion of this drug is not administered during cardiac arrhythmias, atherosclerosis of the coronary or cerebral arteries and lower blood pressure.

In some cases, care should be taken

C care to apply trental with unstable blood pressure and a tendency to a sharp decrease, chronic heart failure, gastric ulcer and duodenal ulcer (tablets), immediately after surgery, and violations of liver and kidney function (in this case, the dosage is adjusted individually) at the age of 18 years (adequate clinical studies for efficacy and safety trental the treatment of children and adolescents are not carried out).

During the course of treatment is necessary to monitor the level of blood pressure. If the patient receives both drugs, lowers blood pressure, insulin The principles of action of insulin - the science of saving lives Tablets for the treatment of diabetes trental dose should be reduced, since the effect of these drugs is synergistic. If at the same time appointed trentalom patient drugs that reduce blood clotting (anticoagulants), the required laboratory monitoring of coagulation parameters.

The risk of bleeding increases with simultaneous appointment trental and nonsteroidal anti-inflammatory drugs (NSAIDs). You should not be combined with any trental drugs, helps reduce blood pressure.

Trental - a drug that has a positive impact on the entire circulatory system, but it has a number of side effects and contraindications, so use only on prescription.

Galina Romanenko

Trental is a drug that improves blood circulation in small blood vessels. This improves blood circulation and circulation as a whole without increasing the load on the heart. This action allows the use trental a variety of diseases.

How does

Trental (active ingredient - pentoxifylline) "charges" smooth muscle cells, red blood cells and platelets more energy. As a result of expanding the lumen of small blood vessels, which relieves stress and stagnation throughout the circulatory system and allows you to freely apply nutrients and oxygen through the blood to the tissues. At the same time improving the quality of red blood cells and the transfer of oxygen to the tissues. Trental prevents platelets from sticking together and form blood clots.

Thus, improving the blood circulation in the whole circulatory system without additional burden on the heart and increased heart rate. If trental administered intravenously, it also contributes to the development of collateral circulation - grow small blood vessels that carry blood to bypass the vessel patency is compromised.

Which diseases prescribed

Trental is prescribed for diseases that are accompanied by impaired patency of blood vessels. Most of these disorders occur against the background of atherosclerosis in blood vessels when atherosclerotic plaque deposited and reduces the vessel lumen. But there may be a violation patency of blood vessels and diabetes mellitus, disorders of innervation of blood vessels, inflammation, hereditary diseases and so on. Especially dangerous are such violations of the heart and brain.

When coronary heart disease (CHD) due to atherosclerosis disturbed patency of the coronary arteries that feed the heart muscle. The heart muscle (myocardium) - a body that works non-stop life, so if any part of it does not receive the next portion of oxygen and nutrients for a few minutes, there is a strong pain in the heart (angina). Then, if the permeability of the vessel is restored, part of the myocardium dies - this condition is called myocardial infarction.

For the prevention of myocardial infarction trental appoint, under its influence blood vessels dilate, red blood cells carry with them more oxygen, and platelets do not form clots. If in this case trental appointed intravenously, it promotes the formation of collaterals - the small blood vessels that will carry the blood to the myocardium in coronary artery bypass altered.

Equally important appointment trental in violation of cerebral circulation. In this case, the atherosclerotic process and zapustevanie blood vessels can lead to ischemic stroke or cerebral infarction, the mechanism of which is exactly the same as the mechanism of myocardial infarction. Trental in this case helps prevent ischemic stroke.

Violations of blood vessel patency arise in diabetes Diabetes - threatening and incurable disease , Often affects the blood vessels of limbs and eyes, which can cause blindness, gangrene of the feet and hands.

In addition, trental indicated for deafness of vascular origin, trophic ulcers, impotence Impotence - a female perspective on the problem   vascular origin, occlusive disease, and other diseases that are accompanied by impaired patency of the blood vessels carrying blood to the tissues.

Contraindications

Trental contraindicated immediately after myocardial infarction, as it can reduce blood pressure, which in this disease and so low. Trental should not be prescribed in a massive defeat of coronary atherosclerosis - if the receptacles have a small lumen throughout, the trental not help and will even help strengthen strokes.

Do not use Trental if any bleeding, including domestic, such as hemorrhagic stroke or hemorrhage in the retina of the eye, which occurs due to rupture of a blood vessel. In this case, trental increase the duration of bleeding.

Do not use Trental if you are sensitive to it and to other xanthine derivatives (caffeine, theophylline, theobromine), pregnancy, breast- Breastfeeding - a personal choice   feeding (trental excreted in human milk).

C care trental prescribed for low blood pressure (BP), chronic heart failure, gastric ulcer and duodenal ulcer (tablets), after recent surgery, disorders of the liver and kidneys, at the age of 18, as well as patients who receive medicines to lower blood pressure.

Side effects

Possible side effects and trentala they appear as headache, dizziness Dizziness - if the ground is slipping from under his feet , Anxiety, insomnia, seizures, redness of the face in the form of hot flushes, reduced salivation, disorders of appetite, constipation, biliary tract disease exacerbations and violations against the background of the liver. There are also visual disturbances, increased heart rate, cardiac arrhythmias, lowering blood pressure, reducing the number of blood cells and reducing its clotting abilities, bleeding, allergic reactions.

Galina Romanenko