Gliatilin ampoules can be applied in the first days after an ischemic stroke or traumatic brain injury, if there were no intracranial bleeding. This allows you to restore the brain as soon as possible and to avoid severe consequences.

How does gliatilin ampoules

Gliatilin (active ingredient - alfostserat choline) as a solution for intravenous and intramuscular injections in ampoules of 4 ml contains 250 mg of active substance per 1 ml or 1 g in 4 ml. Manufactures pharmaceuticals company Italfarmako (Italy).

After parenteral administration (by injection) gliatilin rapidly distributed to tissues, passes the blood-brain barrier and accumulates mainly in the brain, liver and lungs. Proceed starts very quickly.

As is known, after a stroke or trauma to the tissues of the brain lesion is formed, consisting of dead neurons (nerve cells). Around the dead cells are arranged injured cells, which disrupted the nerve impulses. The primary goal of treatment of patients in the acute condition is perhaps more rapid recovery of injured neuronal function, restore nerve impulse conduction through them and creating new ways of nerve impulses, bypassing the dead cells.

Gliatilin ampoules helps to speed up the recovery process of neurons. This happens due to the fact that it decomposes in the body into two substances, taking an active part in the reconstruction of neurons - choline and glycerophosphate. Choline is a source of additional formation of the neurotransmitter acetylcholine in the body through which pulses are transmitted from cell to cell in the brain. Glycerophosphate is also necessary neurons: it turns into phospholipids that strengthen the membrane of neurons.

As a result of recovering gliatilin in neurons metabolism Improves metabolism and losing weight without dieting   and plastic properties - the ability to restore old connections with one another and establish new, bypassing the site of infection.

Gliatilin ampoules in ischemic stroke

Gliatilin ampoules administered in the acute period after an ischemic stroke - sudden acute cerebrovascular accidents due to spasm of blood vessels of the brain, which leads to the appearance of the lesion in the form of dead neurons.

Introduction from the first day gliatilin Gliatilin - stimulates memory   intravenously or intramuscularly help such patients to recover as soon as possible due to the restoration of the injured, but not dead neurons. Once the most acute phase is over, go to the reception gliatilin inside in the form of capsules. The capsules take a long time, during the recovery period, ie up to six months.

Gliatilin administered intramuscularly or intravenously (slowly) in the morning (it has a slight stimulating effect) of a single vial from one to four times a day during the acute phase of ischemic stroke (two - three weeks), then move on to the drug inwardly.

In hemorrhagic stroke Stroke - a serious brain injury Which is accompanied by rupture of a blood vessel in the brain and hemorrhage gliatilin it applied only during the recovery period in the form of capsules. The introduction of the drug in the first days after a hemorrhagic stroke can lead to recurrent bleeding due to increased cerebral blood flow.

Gliatilin in ampoules at traumatic brain injuries

With traumatic brain injuries in the brain as a result of mechanical action also formed lesion surrounded by injured but not dead neurons.

Gliatilin in this case, is administered as soon as possible, but only if there was no intracranial bleeding. Especially effective intravenous or intramuscular administration gliatilin in the case where the victim has severe disorders of consciousness. After the introduction of gliatilin such patients often come to mind. Prolonged use gliatilin first injection, and then in the form of capsules allows faster recover all the functions of the brain after injury.

Enter gliatilin after traumatic brain injuries as well as ischemic stroke.

Contraindications and side effects

Contraindications for intramuscular and intravenous administration are gliatilin idiosyncrasy components of the drug by the body of the patient, pregnancy and breast-feeding Breastfeeding - a personal choice   feeding.

Gliatilin well tolerated and the side effects are known only to allergic reactions and cause nausea, the latter does not require discontinuation of therapy.

Galina Romanenko

Purulent meningitis - a serious disease in which the purulent inflammation develops in the lining of the brain. Such a condition is often complicated by the transition of inflammation to the tissue brain and spinal cord - meningoencephalitis. The disease can cause various infectious agents.

Causes of purulent meningitis

Purulent meningitis - a purulent inflammation of the meninges. The disease can be primary and secondary. Primary purulent meningitis soon develops as the disease of the meninges, while the secondary purulent meningitis is a complication of some other chronic diseases (eg, purulent otitis Purulent otitis - why develop complications   or sinusitis).

The most common pathogens of purulent meningitis are the representatives of the bacterial microflora - meningococcus, pneumococcus, Haemophilus influenzae (influenza coli), Pseudomonas aeruginosa, various types of staphylococci and streptococci, gonococci, Salmonella, E. coli, agents of typhoid and listeriosis.

But sometimes purulent meningitis develops and fungal infection (often it still has purulent, serous character) - cryptococcosis, coccidioidomycosis, and candidiasis. The cause of purulent meningitis can be simple, such as some types of amoebas.

How is purulent meningitis

All primary purulent meningitis are contagious. The disease can be transmitted by airborne droplets. For example, meningococcal infection is transmitted from patients or bacillicarriers when coughing, sneezing, and talking.

But more often purulent meningitis is secondary. And if a good look in the patient's body can be found the site of infection, causative agents of which came from the bloodstream into the cranial cavity and cause meningitis. That's what happens in most cases the spread of pneumococci, Haemophilus influenzae, Streptococcus, Staphylococcus and Pseudomonas aeruginosa, which often cause purulent meningitis.

Fungal infection can be transmitted by airborne droplets and by contact (cryptococcosis, coccidioidomycosis), and enter the cranial cavity through the bloodstream from other foci of infection (candidiasis).

All bacterial purulent meningitis in most cases occurs acutely, whereas fungal prone to prolonged and chronic.

Purulent meningitis meningococcal infection at

The incubation period of meningococcal disease is an average week, but can range from two days to three weeks. The disease can occur in the form batsillonositelstva, acute respiratory infections (ARI), pneumonia, meningokokktsemii (blood poisoning) and meningitis.

Acute purulent meningitis Meningitis - an inflammation of the meninges   may develop on the background of other forms of the disease, and can immediately as an independent form of the disease. Disease begins acutely. If it is started on the background of acute respiratory infections, the patient's condition is deteriorating sharply and suddenly. The patient has a fever, up to very high numbers fever. At the same time it begins to headaches and uncontrollable vomiting.

After a few hours the patient has meningeal symptoms characteristic posture (head thrown back, arms given to the chest, stomach in, for him given his knees), neck stiffness (the patient can not reach his chin chest because stiffness of muscles neck) and so on . Characteristically sharp increase in skin sensitivity, photophobia, fear of loud noises.

A common manifestation of meningococcal infection is a rash that is morbilliform first character, then becomes hemorrhagic, in the form of hemorrhages. Hemorrhage first point there, and then they grow, merge together and rise above the skin.

Symptoms of purulent meningitis are growing very fast, joining cerebral symptoms (impairment of consciousness, psychosis with delusions Brad - not only crazy   and hallucinations), focal neurological disorders in the form of paresis, paralysis, sensory disturbances.

Meningococcal purulent meningitis in adults can occur very hard, but still difficult the purulent meningitis in children Meningitis in children - a dangerous disease Especially in children under one year.

The consequences of purulent meningitis meningococcal origin depend on how quickly the patient was assigned appropriate treatment. In most cases, with proper treatment comes a full recovery, but if such treatment has not been appointed, the patient expects death or recovery with the development of persistent irreversible disorders of the central nervous system.