Glycine: side effects - Rare allergic reactions

June 24, 2012

 glycine side effects
 Glycine - a drug that is usually prescribed as part of a treatment for improving metabolism in brain cells. This drug is very well combined with many drugs used to treat nervous and mental diseases Mental illness - ashamed to ask for help?  Mental illness - ashamed to ask for help?
   and has virtually no side effects.

 Glycine: side effects - Rare allergic reactions

Can glycine have any side effects

Glycine has virtually no side effects because it is an amino acid which is a part of human tissue. Glycine is a natural component of many proteins, it participates in the formation of purine bases (they are then included in the nucleic acids are the basis of heredity) and porphyrins (pigments comprising the many bioactive substances, such as hemoglobin).

On the central nervous system (CNS) Glycine has a calming effect, as it is a neurotransmitter (a substance participating in the transmission of nerve impulses), inhibiting the transfer of excitation. It inhibits the release of glutamic acid, which stimulates the central nervous system and increases the release of other biologically active substances GABA (gamma-aminobutyric acid), has on the CNS inhibitory effect and contributes to a better absorption of glucose, ie, getting more energy required to increase metabolism in brain cells and overall mental performance.

Glycine has antiadrenergicheskim action, that is, inhibits the action of adrenaline - a stress hormone that causes a rise in blood pressure (BP), heart palpitations and increase the number of respiratory movements. In very large doses, it can cause a drop in blood pressure. Such high doses are used in the treatment of ischemic stroke and the effects of traumatic brain injury. Therefore, if the detected blood pressure in patients having a tendency to decrease, assign glycine at very high doses is not necessary.

The only side effect of glycine is an allergic reaction.

Allergies can develop at any substance, including a substance which is a part of a person's own tissues. Therefore, if hypersensitivity to glycine to apply it is not necessary. Allergic reactions to glycine are extremely rare, but it is difficult to predict how it will proceed this process: in the form of an itchy rash, urticaria, angioedema or anaphylaxis. At the same time with each new intake of the drug that causes an allergic reaction, its severity increases.

 Glycine: side effects - Rare allergic reactions

When glycine bring relief to the patient

Glycine - is a drug that affects the metabolic processes (metabolism) in brain cells. It's a long process, so in order to exert its therapeutic effect, it takes time. Moreover, in most cases glycine administered as part of a treatment. It enhances the effect of anticonvulsant, calming (sedative), removing anxiety, mood-enhancing drugs. Glycine also reduces the side effects of these drugs.

It is used in treatment of various neurological and psychiatric disorders which are accompanied by increased irritability Irritability - you try to control my temper  Irritability - you try to control my temper
 , Aggression, violation of social adaptation, anxiety Anxiety - how to distinguish normal from disease?  Anxiety - how to distinguish normal from disease?
 , Depression, reduced mental capacity. Under the action of glycine these symptoms gradually decreased.

A distinctive feature of glycine is its ability to affect the metabolism Improves metabolism and losing weight without dieting  Improves metabolism and losing weight without dieting

This allows it to some extent to suppress the craving for alcohol and opiates in patients with chronic alcoholism and opiate addiction. He was always prescribed to such patients as part of a treatment.

Since glycine increases the release of GABA in neurons, which enhances the ability of neurons to absorb glucose in the cells increased energy metabolism. A large amount of power is always activated and all other types of metabolism. Including activated protein metabolism, which contributes to the restoration of neurons damaged in some pathological process or trauma. These processes lead to increased mental performance, memory and some improvement in the recovery of intelligence. In addition, such action glycine helps to suppress craving for sweets, so glycine is sometimes prescribed in the complex treatment of obesity.

Glycine has a special significance in the treatment of the effects of traumatic brain injury and ischemic stroke. Restoration of metabolism in the damaged but still alive neurons allows you to clearly separate the lesion of the brain (ie dead cells) and restore lost connections between neurons. This promotes more rapid rehabilitation of patients.

Glycine - a drug that has almost no side effects.

Galina Romanenko

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  • glycine

Aseptic meningitis - non-bacterial origin

November 8th, 2013

 aseptic meningitis
 Aseptic meningitis Meningitis - an inflammation of the meninges  Meningitis - an inflammation of the meninges
   may be infectious (viral) the nature and non-infectious - to develop, for example, against the background of a tumor or an injury to the brain or spinal cord. This type of meningitis has similarities with other types of meningitis, and unlike them. As a rule, it also gives fewer complications than purulent meningitis, bacterial, fungal or protozoal origin.


Causes aseptic meningitis

Aseptic meningitis - an inflammation of the meninges, which can be caused by both infectious and non-infectious factors. Because infectious agents cause aseptic meningitis can be viruses. Most often, it enteroviruses, arboviruses (eg, tick-borne encephalitis, Crimean hemorrhagic fever), HIV, herpes simplex virus type-2. Less common cause of aseptic meningitis herpes simplex virus type 1, lymphocytic choriomeningitis virus, mumps virus. Very rarely the cause of aseptic meningitis are adenovirus, cytomegalovirus Cytomegalovirus - what is its danger?  Cytomegalovirus - what is its danger?
 , Epstein-Barr virus (causes mononucleosis), influenza viruses A and B, measles, parainfluenza, rubella, shingles.

At times, the incidence is distributed as follows: in the winter and spring of mumps meningitis are more common in summer and autumn - enterovirus and arbovirus, autumn and winter - caused by lymphocytic choriomeningitis virus. Meningitis caused by HIV and herpes simplex virus Herpes simplex - in fact, not so simple  Herpes simplex - in fact, not so simple
   can grow year-round.

Aseptic meningitis infectious origin is most often associated with brain tumors. But it can also develop after the use of certain medications (eg, nonsteroidal anti-inflammatory drugs, gammagolobulina), against the backdrop of some systemic diseases (for example, against the background of systemic vasculitis, sarcoidosis).


Aseptic meningitis is viral

Aseptic meningitis is viral, in most cases a benign and does not leave behind the effects. The most common Enterovirus meningitis Enterovirus meningitis - the most common type  Enterovirus meningitis - the most common type
 Which occurs acutely, with fever, headache, severe meningeal symptoms, but as a rule, does not leave consequences.

Much less common in our country mumps meningitis, which is also a feature of the acute course with fever and headaches, but when it come to the fore not meningeal and cerebral symptoms - weakness, dizziness, and sometimes - seizures.

When HIV aseptic meningitis, usually develops at the time the blood of the patient-specific antibodies to the virus. Manifestations of this meningitis are often unspoken nature of temperature may rise as insignificant and very, headaches, meningeal symptoms, sometimes the defeat of the cranial nerves, confusion and sleepiness. Typically, such a meningitis does not require any treatment other than the treatment of HIV infection and painkillers.


Aseptic meningitis is a non-infectious

Most often, aseptic meningitis develops in the brain tumors. The first aseptic meningitis in the brain tumor has been described in the 30s of the last century. Today, found that aseptic meningitis - not uncommon, it occurs in the postoperative period, not only after the removal of brain tumors, but also in the surgical treatment of malformations and other diseases of the central nervous system.

Aseptic meningitis is an inflammatory response to surgical trauma of the brain. This reaction occurs in all patients after a neurosurgical intervention (removal of a brain tumor), which is confirmed by immunological studies.

Manifested a meningitis high fever headache, meningeal symptoms (for example, a symptom of stiff neck when the patient can not bend his head) and the lack of growth of focal neurologic symptoms (paresis, paralysis, sensory disturbances).



For all types of aseptic meningitis in patients' blood shows signs of inflammation: increased number of white blood cells (leukocytosis, especially the increased number of lymphocytes) and accelerated ESR. In the cerebrospinal fluid revealed lymphocytic pleocytosis (an increase in the number of cellular elements with a predominance of lymphocytes among them), high protein content, the negative results of bacteriological examination of the spinal fluid, but the PCR method it is possible to detect viruses.



Treatment of symptomatic aseptic meningitis. If the condition of patients with severe (for example, enterovirus meningitis), for its ease of doing a spinal tap - removal of the liquor reduces intracranial pressure and improves the patient's condition.

Assign also diuretics administered detoxification solutions. If meningitis caused by herpes infection, prescribed antiviral drugs (acyclovir, valacyclovir, Famvir), antipyretics and analgesics.

Forecast favorable aseptic meningitis.

Galina Romanenko

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  • types of meningitis