- Liver cancer: prognosis is poor, but there is hope
- As shown
Liver cancer can arise from many different causes. But the main predisposing factor for the occurrence of this disease is cirrhosis of the liver - the replacement of liver tissue by connective tissue as a result of a serious illness or some toxic effects, such as the regular use of alcohol.
Causes of liver cancer
Liver cancer can occur in the background of cirrhosis, parasitic infestations, severe hepatitis, alcohol abuse. The incidence of liver cancer varies between countries that may be associated with the peculiarities of life, climate, national peculiarities of nutrition, all sorts of diseases (including viral) or parasitic infestations in the area, a genetic predisposition. For example, in several countries in South-East Asia and Africa, liver cancer makes up half of all malignant tumors. In most developed countries liver cancer occurs much less frequently, usually accounting for no more than 3% of all cancers.
Developing liver cancer, usually after forty years, more frequently in men than in women. There are gnarled, massive and diffuse (spread over the whole body) form of tumor growth. Nodosum is the most common form and is characterized by single or multiple nodes of various sizes. Around the major components can be placed small metastatic nodules. When the massive form of liver cancer, a large tumor site usually takes the right lobe of the liver. Diffuse form is manifested scattered throughout the tissues of the liver tumor nodules.
Metastatic liver cancer are characterized by intrahepatic seeding. Often affects hepatic lymph nodes at the gates of the liver (liver gate - a place of entry and exit of blood and lymph vessels and bile ducts).
As shown
Manifestations of liver cancer are varied. Characteristically imperceptible beginning, the absence of clear signs of the disease and its rapid development. Persistent symptoms of liver cancer are weakness, weight loss, decreased performance. Often there is a lack of appetite, nausea,
Nausea - there may be problems with the nervous system
, Vomiting, fever. From the local manifestations characterized by a feeling of heaviness, distention and pain in the right upper quadrant in the upper abdomen, enlarged liver. When probing the tumor, tenderness in the upper abdomen. Later, signs of the disease are mild jaundice, enlargement of the superficial veins of the anterior abdominal wall, the appearance of large amounts of fluid in the abdomen (ascites), sometimes increases the spleen.
When the diffuse form of liver cancer symptoms are caused by the tumor, as if superimposed on signs of cirrhosis. The liver in these cases increased slightly, and the tumor is not detectable. Observed anemia, ascites, progressive weight loss.
Timely detection of liver cancer is very difficult. This is due to its lack of clear signs of cancer on the background of the previous diseases and large compensatory capacity of the liver (liver tissue changes even for a long time to perform its functions). The most important, but late symptoms of cancer
Fifteen signs of cancer that women ignore
Liver is its progressive increase, hard and uneven surface of the liver, which is determined at a palpation, ascites and intra-abdominal bleeding.
Identify liver cancer allow radioisotope and ultrasound diagnostics, computed tomography (CT), magnetic resonance imaging (MRI). In some cases, for diagnostic purposes is performed endoscopic surgery (laparoscopy) from taking a piece of liver tissue for testing. Confirms the diagnosis and laboratory tests: blood of patients show anemia, leukocytosis
Leukocytosis - when there are too many white blood cells
, Accelerated erythrocyte sedimentation rate, and signs of liver dysfunction.
Medical intervention
Treatment of liver cancer usually combined. Radical surgery should include not only the removal of the tumor, but resection of the liver. To perform a resection is important that the tumor has not reached the gates of the liver. Conditions for resection are considered unfavorable, if the tumor is located deep in the liver tissue. In some cases, a liver transplant.
After surgery, radiation therapy is performed. Also, receive chemotherapy
Chemotherapy - it always falls the hair?
: Drugs that suppress tumor development, is placed directly into a vein or artery of the liver when catheterization. In this vein can be administered and means improving liver function.
Contraindication for liver resection are scattered its destruction, the spread of the tumor at the gate of the liver, acute for cancer, severe liver dysfunction.
The prognosis of adverse liver cancer, as this disease is rarely possible to identify at an early stage. When a liver transplant may cure.
Galina Romanenko