Eye ointment Dexamethasone
Dexamethasone - one of the most effective glucocorticosteroids
produced by several manufacturers. As an example we can take dexamethasone ophthalmic ointment that makes the Belgian pharmaceutical company Alcon Couvreur-called maksideks. This ointment is used to treat many eye diseases.
The mechanism of action of eye ointment maksideks
Active ingredient ointment maksideks a glucocorticosteroid (GCS), dexamethasone - analogue of natural corticosteroids, which are produced by the adrenal cortex of man. Produced 0, 1% ophthalmic ointment maksodeks in the aluminum tube 3, 5 g (1 g of ointment contains 1 mg dexamethasone).
When laying the ointment of the lower eyelid active substance dexamethasone rapidly penetrates the surface layers of the eye and acts mainly locally, providing anti-inflammatory, anti-allergic, anti-edema effect. Under the influence of deksometazona there is a narrowing of the small blood vessels (capillaries) and a decrease in permeability, redness of the sclera passes, swelling, and all the other signs of inflammation or allergies. This occurs due to the fact that dexamethasone inhibits the formation, transport and activity of biologically active substances involved in these processes.
Like any other dosage forms of dexamethasone ophthalmic ointment maksideks not be used for a long time - it can lead to several side effects, including general, as part of yet dexamethasone into the bloodstream.
The main side effect of eye ointment maksodeks is its ability to significantly reduce the immune system, which often leads to the attachment of a bacterial or fungal infection
Fungal infection: to prevent and defeat
. Often this infection can not be noticed immediately as dexamethasone inhibits any inflammation.
Because of the risk of common side effects of the ointment is used to treat children and adolescents as well as dexamethasone is able to influence their growth and sexual development.
With which diseases and how to apply
Eye ointment dexamethasone maksodeks nonsuppurative prescribed for inflammatory and allergic processes in the eye:
- in inflammation of the surface layers of the eye - the edges of the eyelids, conjunctiva, sclera and cornea (blepharitis, conjunctivitis, scleritis and keratitis);
- in inflammation of the iris, ciliary body and choroid (iridotsiklitah and uevitah);
- for the prevention of inflammation after burns and eye after an eye operations (just after the defect surface layers of the eye is completely healed).
Ointment maksodeks for a lower eyelid in the form of a long strip from one half to see two or three times a day for a maximum of two to three weeks.
Contraindications
Contraindications for use of eye ointment maksodeks are:
- Hypersensitivity to the components of the patient maksodeks ointment;
- eye diseases with viral, fungal, bacterial or purulent tubercular nature;
- damage to the surface layers of the cornea;
- breast-feeding;
- childhood and adolescence - clinical studies of the drug in these group of patients have not been conducted.
During pregnancy, the use of eye ointment maksodeks possible only on prescription in the case, if the expected benefit to the mother's body exceeds the potential risk to the fetus.
Side effect
If you apply eye ointment prescribed by a doctor maksodeks short courses, the side effects usually do not happen. If ointment is used for a long time (more than ten days), it may cause side effects in the form of:
- the gradual development of glaucoma
Glaucoma - a perspective possible blindness
- Persistent increase in intraocular pressure, which is accompanied by severe headaches;
- lesions of the optic nerve with visual impairment;
- clouding of the lens - cataracts
Cataracts - how to solve the problem completely?
;
- slow healing of wounds - if the ointment is applied after injuries and burns;
- if the patient had corneal thinning, prolonged use of eye ointment maksodeks may result in perforation;
- as the ointment reduces immunity tissues of the eye, may join purulent bacterial or fungal infection, which is masked by dexamethasone, removes all the phenomena of inflammation;
- allergic reactions such as redness and edema - in this case the ointment immediately canceled.
Eye ointment maksodeks - is an effective drug, which, however, has many side effects, so it should be used only if prescribed by a doctor with all the indications and contraindications, and short courses.
Galina Romanenko