Hemorrhagic vasculitis "loves" mostly young. For the first time the disease has been described in the early 19th century, the main contribution to the description of his symptoms was introduced first I.Sheleynom and then Henoch. Nature hemorrhagic vasculitis was established gradually over more than one hundred years.

What is a hemorrhagic vasculitis

This disease is also known as Henoch's disease or kapillyarotoksikoz. It is an aseptic (without infection), inflammation of the capillary action caused by the damaging immune complexes. Manifested kapillyarotoksikoz hemorrhages (bleeding), violation of intravascular clotting disorder and the blood circulation in small blood vessels.

Kapillyarotoksikoz is infectious and allergic diseases, based on the violation of immunity. As a result of immune disorders caused by various reasons, the immune system produces antibodies which are connected to the antigen forming immune complexes deposited on tissues and destroy them. Fabric - targets in this case are the walls of the small blood vessels (capillaries). In chronic forms of the disease, it often takes on the form of autoimmune, allergic to its own tissues.

As a result of the activation of enzyme systems vessels dilate their increased permeability, immune complexes and then penetrate deeply into the vessel wall and cause necrosis, leading in some cases to considerable changes in various organs. The pathological process when kapillyarotoksikoz localized in the skin, joints, kidneys and gastrointestinal tract. Sometimes it affects the blood vessels of the lungs and brain.

The reason for this failure of immunity can be infections (bacterial or viral), medicines, the introduction of vaccines and serums, food, worm infestation, hypothermia, prolonged sun exposure, injury and so on. It is also believed that there are genetic characteristics and immunity.

Symptoms

The disease can occur acutely and even lightning and can have a chronic relapsing course.

The acute form kapillyarotoksikoz runs hard. Through one - three weeks after the previous infection, vaccination, drug administration and so on. the patient has malaise, headache, fever, aching joints Joint pain - how to understand what is going on?   and in the stomach. Against this background, the skin of legs, buttocks, abdomen side surfaces quickly appear hemorrhagic rash. At the same time may appear sharp cramping abdominal pain, bloody diarrhea and vomiting with blood. Sometimes, there are the main symptom of severe pain in the joints.

Chronic recurrent form is manifested by skin, joints, kidneys and gastrointestinal tract, or various combinations of these lesions. Skin-articular form is often called simple.

The skin lesion is found in most adult patients, while the rest of defeat does not occur at all - it is more common in children. Hemorrhagic rash appears on the skin in waves, in the form of individual elements or groups. In most cases the rash is located on the front surface of the lower legs, feet, thighs, buttocks, arms, shoulders, around the affected joints. The back, chest and face are rarely affected. The rash initially have a bright red color, then gradually fade away, and by the end of the third day disappear altogether. Most eruptions are accompanied by severe itching or burning sensation.

Joint damage often begins simultaneously with rashes on the skin, but sometimes a few days after the rash appears. There are a lot of pain and swelling in the large joints - the knee, ankle. A few days later the pain is like, change does not occur in the joints.

The hardest runs defeat of the gastrointestinal tract. Sometimes abdominal pain Abdominal pain: Types and Symptoms   even before the rash appears. They arise with the appearance of hemorrhages in the intestinal wall and are cramping in nature. Often, these pains occur in the navel, in the right iliac, hypochondrium and resemble a picture of acute abdomen caused by appendicitis, intestinal obstruction or perforation of the ulcer. Pain kept basically three days. But sometimes up to ten days. They are often accompanied by nausea and vomiting of blood, and blood in the stool. In some cases, developing intestinal bleeding, which is accompanied by a sharp decrease in blood pressure and collapse.

Renal proceeds as chronic or acute glomerulonephritis Glomerulonephritis - a severe infection of the kidneys , Often developing after two to four weeks after the onset of disease and is characterized by the appearance of blood and urine protein. Blood pressure rises rare. Glomerulonephritis may disappear after a few weeks. But sometimes it becomes chronic and goes unnoticed that in a few years may lead to a complete loss of kidney function.

Duration of chronic forms kapillyartoksikoza can be different - it depends on the destruction of an organ.

Rheumatocelis Vasculitis - when blood vessels refuse to work   - A serious illness that requires hospital treatment.

Galina Romanenko

Troxevasin - a drug, efficacy and safety of which is time-tested. It tones the smooth muscles of the walls of the veins, has a beneficial effect on the capillaries, inhibits the action of toxic free radicals. Furthermore, it is well reduces swelling resulting in stasis of venous blood, and anti-inflammatory effect.

How does troksevazin

Troxevasin (troxerutin) is a semisynthetic derivative of routine - bioflavonoids contained in the leaves of rue fragrant. Rutin, especially in combination with ascorbic acid has a positive effect on capillary walls, reducing their permeability and fragility. Troxevasin more active than natural routines. It not only strengthens the walls of blood vessels and reduces swelling, inflammation of the walls of the veins, preventing the formation of blood clots.

It significantly enhances the effect of ascorbic acid, also strengthens the walls of blood vessels. This happens due to the fact that troksevazin inhibits toxic effects of free radicals and oxidation of ascorbic acid.

Particularly important beneficial effect troksevazin to the smallest blood vessels (capillaries), which, however, play a crucial role in the formation of varicose veins. Under the effect of increased tone troksevazin capillary walls, thereby promoting venous blood in the right direction from the bottom upwards.

When thrombophlebitis and related eating disorders troksevazin surrounding tissues reduces inflammation in the walls of the veins, tones the walls of veins, relieves congestion and swelling in the tissues. All together, this leads to better nutrition of soft tissues surrounding the zone of disturbed venous circulation. If this area were sores, the application troksevazin promotes their full or partial healing.

If ingestion troksevazin enters the bloodstream, acting for eight hours, then decomposed by the liver and excreted primarily in the urine, but also partly in the faeces (bile).

In some cases, treatment is indicated troksevazin

Troxevasin prescribed mainly for chronic venous insufficiency Venous insufficiency - rapidly Youthful disease . This disease may be accompanied by edema, malnutrition tissue, trophic ulcers, inflammation and venous thrombosis. All these phenomena when taking troksevazin can significantly decrease. If you start taking troksevazin at the beginning of the formation of venous insufficiency, the progression of the disease may be a long pause.

Troxevasin can be used in many vascular disorders. For example, diabetes Diabetes - threatening and incurable disease At which damage the blood vessels often leads to gangrene of the extremities.

Troksevazin also help with hemorrhoids - venous stagnation of blood in the veins of the rectum. In chronic hemorrhoids troksevazin warn formation of blood clots and the transition to an acute chronic course. If acute hemorrhoids has already begun, the troksevazin reduce swelling, pain and inflammation.

Apply troksevazin and increased bleeding - strengthening the walls of blood vessels prevents the appearance of skin hemorrhages, typical for such diseases.

For some children the infection affects the small blood vessels, which increases the intensity and duration of the inflammatory process. Such diseases include measles Measles in children - may cause serious complications   and scarlet fever. Troxevasin in this case as part of a prescribed treatment. By the same disease, and include the flu, which can affect people of any age.

How to apply

Frequently troksevazin applied simultaneously and orally (capsule), and outwardly in a 2% gel.

Inside troksevazin take during the meal, do not chew the capsule with water. First take one capsule (300 mg) three times a day for two weeks. During this time it will be seen how effective the action of the drug. After this dose or reduce or leave unchanged, and continue treatment for a total of up to a month. After treatment, the therapeutic effect lasts for another month.

When vascular changes in diabetes mellitus troksevazin dose is adjusted individually and is usually higher than the recommended for the treatment of varicose veins.

External and local use 2% gel troksevazin, it is applied to the skin over the site of the lesion and rub gently until complete absorption.

In what cases can not be used troksevazin

Troksevazin not use in case of hypersensitivity to it the body of the patient. For external and local application troksevazin a 2% gel no other contraindications.

The capsules should not be used as troksevazin ulcerative processes in the stomach and intestines in the acute stage, in the first trimester of pregnancy. With care it is used during pregnancy, breast- Breastfeeding - a personal choice   breast and kidney function.

Troxevasin help patients with a variety of cardiovascular problems.

Galina Romanenko