Mycoplasma genitalium was open later than other species of mycoplasmas, about thirty years ago. Today, the organism is not yet fully understood, but it is clear that it is the most pathogenic mycoplasmas views as often causes lesions urogenital organs with significant clinical manifestations.
Mycoplasma genitalium Features
Under the electron microscope, it is seen that Mycoplasma genitalium is slightly elongated and tapered to an end shape similar to the tip. Like all mycoplasmas, the microorganism has a genome (hereditary set of genes), which is considerably smaller than the other species of mycoplasmas.
To grow on nutrient media mycoplasma genitalium is difficult, as it grows very slowly - from one to five months. This is explained by a small number of genes are involved in the decomposition of nutrients.
Therefore, the only method of diagnosis is by far the PCR (polymerase chain reaction).
This is a very accurate method that detects a gene of a microorganism.
Mycoplasma genitalium A special feature is the fact that it can produce some sliding motion, which allows it to penetrate into the mucus covering the mucosal cells urinary organs (epithelium). Infiltrating cells epithelium microorganism tightly attached thereto by means of receptor containing neuraminic acid. This causes an inflammatory response in the epithelial cells.
Mycoplasma genitalium, and the human body
Mycoplasma genitalium has high pathogenicity with respect to the epithelial cells of the urogenital organs and highly contagious, that is almost always transmitted sexual partner.
Currently, research is carried out to identify the role of this organism in the occurrence of inflammatory diseases of the pelvic organs (PID). Obviously, the introduction of urogenital Mycoplasma genitalium human organs significantly reduces local immunity
Immunity - types and characteristics in children in adults
and increases the risk of getting a partner with HIV.
What diseases Mycoplasma genitalium can cause men
Most often, this organism is the cause of urethritis negonokokkvogo
Urethritis - a very male disease
(NGU) in men. Symptoms of the disease appear after one - three weeks after getting it to the mucous membranes of the urinary organs. The disease almost immediately takes a chronic recurrent nature. The complication of this process are often chronic prostatitis.
Nevertheless, such asymptomatic urethritis hardly occurs unlike urethritis caused by other species of mycoplasmas. In a study of men with NGU were found Mycoplasma genitalium frequent combination with other bacterial and viral infectious agents. But very often this agent combined with Trichomonas.
Furthermore, it was found that the Mycoplasma genitalium is able to be attached to the sperm and to reduce their functionality (including mobility), and this may eventually lead to the development of male infertility.
What diseases Mycoplasma genitalium can cause women
In women, the pathogen is detected more often in inflammatory diseases of the pelvic organs (PID). Very often it is isolated in acute endometritis and adnexitis - inflammation of the uterus with appendages. Already it established that the Mycoplasma genitalium can cause tubal infertility, but fully part of this pathogen in the development of different types of infertility in women has not been established.
As revealed
All mycoplasma virtually impossible to detect by microscopy, as it is very volatile microorganisms. Therefore, combined with the surface of the urinary organs smears under the microscope is not investigated. Sowing on nutrient medium is also impossible - Mycoplasma genitalium grows too slowly.
Therefore, the only way to detect Mycoplasma genitalium is a PCR - studied scrapings taken from the urogenital organs of men and women.
Getting rid of mycoplasma genitalium
It was found that Mycoplasma genitalium is sensitive to antibiotics
Antibiotics - whether they will help you in the foreseeable future?
tetracycline and macrolides.
Mycoplasma genitalium is particularly sensitive to azithromycin (Sumamed). Because the microorganism grows very slowly, azithromycin is not assigned in the usual recommended instructions scheme. In the first day take 500 mg of the drug, and from the 2nd to the 5th day - about 250 mg. This method is usually azithromycin provides complete freedom from mycoplasma
Mycoplasma - the smallest microbe
genitalium.
Mycoplasma genitalium is by far the most pathogenic mycoplasmas views. The study of this organism and its effects on the human body is still ongoing.
Galina Romanenko