Kondilin - antitumor agent of high efficiency - Indications and contraindications

March 28th, 2010

  • Kondilin - antitumor agent of high efficiency
  • Indications and contraindications

The mechanism of action kondilina

Kondilin (INN - podophyllotoxin) is the most active component podofillina - antitumor agent of vegetable origin obtained from the roots of the plants podophyllum peltatum podofilla tincture of roots have long been used in folk medicine as a laxative, emetic and anthelmintic agents. It is now established that they possess cytostatic activity, i.e. stops cell division. Since all tumors are characterized by rapid growth of tissues (i.e., cell division), the drug is used as an antitumor agent, mainly in the treatment of genital warts Treatment of genital warts  Treatment of genital warts
 . When applied topically kondilin causes necrosis (necrosis) of the external genital warts, as well as providing a cytostatic, cauterizing and mummified, reduces the severity of inflammation.

External application kondilina causes a slight suction to the blood for an hour after it is applied. In the blood, the drug does not accumulate and is excreted in the urine and feces.

Available kondilin pharmaceutical firm "Astellas Pharma Europe BV" (Netherlands) in the form of 0, 5% solution for external application with the accompanying applicators.

 Indications and contraindications | Kondilin - antitumor agent of high efficiency

Indications and contraindications

Indications for use kondilina is a topical treatment of genital genital warts - tumors of the size of 2-6 mm on the mucous membranes of the genitals and anus, caused by human papillomavirus. Top of genital warts wider base, hilly, sitting on a thin stalk. They grow very quickly, in just a few hours, the whole forming a "thicket" growths.

Contraindications for use kondilina are: individual intolerance of components, pregnancy; breast-feeding Breastfeeding - a personal choice  Breastfeeding - a personal choice
   feeding, child up to 12 years and the use of other drugs containing podophyllotoxin.

 Indications and contraindications | Kondilin - antitumor agent of high efficiency

Signs of overdose and side effects

When applied topically kondilina in large quantities should be washed off with soap and water. If you accidentally taking into kondilina may be nausea, vomiting, fever, diarrhea, ulceration of the oral mucosa. In this case it is necessary to wash out the stomach and consult a physician as necessary laboratory monitoring of the body.

Side effects when using kondilina may take the form of local reactions and allergies. Locally, the second - the third day of the drug may cause redness, swelling, some painful, ulceration of the mucous membrane surface of the warts. If you have large warts in the penis may develop swelling and infection accession. Allergic reactions are possible.

 Indications and contraindications | Kondilin - antitumor agent of high efficiency

How to use kondilinom

Use kondilin own patient can not, as well as the penetration of the drug on healthy skin or mucous membranes may cause severe irritation and ulceration. Therefore, treatment can only be carried out by the doctor.

Before applying kondilina should wash affected areas with soap and water and dry well. On the surface of warts drug is applied by special applicator dipped in the drug solution. Kondilin be discharged only on the warts, particular caution should be exercised in the localization of warts in the area of ​​the foreskin, as there is very thin and sensitive skin Sensitive skin: causes and care  Sensitive skin: causes and care
 . After application the place applying the solution must dry thoroughly to avoid irritation of healthy skin in contact with the acuminata. The total duration of treatment should not exceed five weeks. To reduce the risk of large amounts of drug absorption into the blood treatment surface area in an amount not exceeding 10 cm square, and the amount of solution used - 0, 5 ml per day.

In applying kondilina Avoid contact with the eyes, it can cause severe irritation of the conjunctiva. In such cases, the eye is an urgent need plenty of water. Irritation, skin ulceration and the mucosa around the genital warts can be prevented with the help of neutral cream or Vaseline Vaseline: old friend  Vaseline: old friend
 Which is applied to healthy tissue before applying kondilina.

Kondilin - quality effective drug for the treatment of genital warts in the doctor's office.

Galina Romanenko

Article Tags:
  • kondilin

Stomach flu - rotavirus infection of the new sample - Diagnosis and treatment

April 3, 2011

  • Stomach flu - rotavirus infection of the new sample
  • Diagnosis and treatment

 stomach flu diagnosis treatment

As infected stomach flu

Gastric or intestinal flu Intestinal flu - rotavirus which affects the intestinal tract  Intestinal flu - rotavirus which affects the intestinal tract
   is an infection that is caused by rotavirus, and accompanied by vomiting, diarrhea, abdominal pain and general violations of the patient.

You can become infected with rotavirus by a sick person by direct contact (for example, when a handshake), through various objects, which he enjoyed, food, water. Sometimes gastric flu outbreaks occur in camps, located near water (infection occurs by ingestion of water). But more often this disease affects children of preschool age. After recovery, recover from a person for a period of time can be a carrier of the virus and it can be infected with rotavirus.

Once in the body rotavirus settled in the small intestine, it is embedded in the wall and begins to multiply, inhibiting the enzymatic activity of the intestine. Reduced secretion of enzymes leads to the fact that disrupted cleavage complex carbohydrates, they accumulate in the intestine, attracting the water - there is diarrhea.


Symptoms of stomach flu

After contact with the infectious agent into the human body passes from one to five days before showing signs of disease. This time period is called the incubation period. After that, the child is usually high fever (sometimes the temperature rise does not happen), there are nausea, vomiting, abundant loose, watery stools and abdominal cramping Abdominal pain: Types and Symptoms  Abdominal pain: Types and Symptoms
 . If moderate course of disease vomiting is usually not more than 4 times per day, loose stools - more than 10 times. In severe cases, vomiting and diarrhea are permanent, the child loses fluid and dehydration occurs.

The chair at the stomach flu is foamy-watery and pronounced odor. It occurs during the lung disease without an increase in temperature and a more formalized (mushy) chair.

Stomach flu is always accompanied by great weakness and malaise, these symptoms are all the more pronounced, the more the child loses fluid. The loss of large amounts of fluid is accompanied by changes in the body, called exsicosis. The child has a characteristic form: facial features are sharp, his eyes sunken, his lips dry and cracked, he was constantly asked to drink.

Since the stomach flu is a viral infection, it is almost always accompanied by a small lesion of the upper respiratory tract, which is manifested cough and runny nose.


Diagnosis and treatment of gastric flu

Diagnosis of gastric flu can be suspected in the mass infection of people in the community, and manifestations of disease, characteristic of rotavirus. Before laboratory confirmation of the disease is considered to be simply an intestinal infection. In a laboratory study of feces and vomit in the virology laboratory they found rotaviruses. In the blood of patients can also detect antibodies Antibodies - "soldiers' immunity  Antibodies - "soldiers' immunity
   to rotavirus. But as virology lab is not everywhere, the diagnosis of rotavirus infection is rarely placed.

Specific treatment of gastric flu does not exist. Over the course of the disease is observed, making up for the loss of body fluids (child watered spoon various liquids: slabozavarennogo tea, salt solutions, just water). If a patient shows signs of exsicosis, it is hospitalized and intravenously injected the fluid, thus preventing further dehydration.

The disease stomach flu Influenza - expect the unexpected but always  Influenza - expect the unexpected but always
   It is the enzyme deficiency, so patients are appointed by the enzymes in the form of medications (eg, festal). Patients received diet food - boiled only pureed food. Eating need 5-6 times a day, in a small volume. For removal from the intestine of toxic substances and pathogens prescribed medications that they can absorb and excrete.

Since the mucous membrane of the gastrointestinal tract is inflamed, there is activation of conditionally pathogenic and can join a bacterial infection. To avoid this, the patient is prescribed probiotics (beneficial bacteria they contain - the inhabitants of the human intestine) and prebiotics (contain substances that promote self-reproduction of normal intestinal microflora).

Gastric flu prevention is personal hygiene.

Galina Romanenko

Article Tags:
  • flu