Cardiomagnyl - a drug, which is composed of acetylsalicylic acid (aspirin) and magnesium hydroxide which reduces the side effects of aspirin. During pregnancy, aspirin is better not to take - it can have a negative impact on both the child's body and the body of the mother.
Cardiomagnyl I trimester of pregnancy
In the hours I trimester (12 weeks) of pregnancy there is a bookmark tissues and organs of the fetus. At this time it is not recommended to take any, even the safest of medicines without a prescription. Aspirin is not a safe drug, as clinical studies have confirmed the ability of this drug to cause fetal malformations (teratogenic). The majority of malformations formed in the I trimester of pregnancy, when embryonic cells divide rapidly to form the organs and tissues.
Aspirin is able to cross the placenta and cause congenital malformations such as cleft lip, cleft palate, malformations of various organs, hypoplasia of limbs and so on. Which defect develops in a child depends on the dose, the duration of his admission, and gestational age, that is, on what is the organs and tissues are laid while taking aspirin
Aspirin - NSAIDs
. Thus, the tab and the development of the cardiovascular system of the embryo has to 20-40 days after conception
Conception, ovarian cycle, fertilization and genetics of a child
, Arms and legs are laid on the 24-46 day of the nervous system - in the 15-25 day. In the days listed from taking aspirin suffer the most intensely developing organs and tissues.
It was found that most of the anomalies develops during the second and third week of pregnancy, when a woman does not know that she is pregnant and can take a variety of medications. During the first weeks of pregnancy, the embryo is not yet associated with a woman's body: the fertilized egg is still progressing through fallopian tubes, receiving power from the inventory inside the egg. At the end of the first week of the egg gets to the uterus, and is embedded in the mucous membrane, after which the embryo and the woman's body begins to form a common circulation and nutrients come to the embryo through the blood. In that time until the end of I-trimester fetus is very vulnerable to various influences, especially, for the effects of drugs are teratogenic.
Cardiomagnyl in II trimester
In the second trimester of pregnancy, the placenta gradually begins to function, through which the bulk of the drug does not pass. In addition, the laying of the main organs and systems most complete, but the process is largely an individual and sometimes tab organs and tissues takes some more time.
Cardiomagnyl - a drug that is used as a prophylactic measure mainly in inclination to thrombosis. If these diseases are found in a pregnant woman, she for the prevention and treatment prescribed other medications that do not adversely affect the fetus, such as various preparations of heparin. Therefore, in the II trimester of pregnancy need to accept cardiomagnyl not. The risk is on its reception still remains, so take cardiomagnil in this period of pregnancy is not contraindicated, but it can be taken only on prescription, which determines the ratio of benefits and risks of its reception.
Cardiomagnyl in the III trimester of pregnancy
In the III trimester of pregnancy cardiomagnil again allowed to take. For this there are many reasons. First, during this period the reception cardiomagnyl may affect the state of the cardiovascular system of the child - under its influence may prematurely close the ductus arteriosus in the fetus. Arterial (Botallo) duct connects the aorta to the pulmonary artery of the fetus. As long as the fetal lungs are compressed by the blood flow, bypassing the lungs, it enters the systemic circulation, after the birth arterial canal is closed. If arterial canal close to the birth of the fetus, it can be broken intrauterine blood circulation.
Admission cardiomagnyl can cause increased bleeding in pregnant women, which is very dangerous before delivery. The child increased bleeding can lead to birth trauma
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For example, in intracranial hemorrhage.
Mechanism of analgesic and anti-inflammatory action cardiomagnyl based on the fact that it inhibits the synthesis of biologically active substances prostaglandins, are actively involved in inflammatory processes. But there are other prostaglandins that activate a generic activity after the onset of labor. Cardiomagnyl inhibits the synthesis of prostaglandins, and that could slow down generic activities and lead to various complications in the mother and fetus. It can also reduce adaptive capacity of the child after birth.
Furthermore, at the end of pregnancy with special load the liver and kidneys - organs, which contribute to the removal of acetylsalicylic acid from the body. In this case, an increased risk of delayed release
Discharges in women when there is cause for concern
of the drug from the body.
Cardiomagnyl during pregnancy is best not to take.