Pariet and pregnancy - use of the drug during pregnancy and breastfeeding
Breast-feeding: feed - and no nails!
It is contraindicated, as it may enter the bloodstream and together with it through the placenta to the fetus. Pariet may also be allocated to human milk. What happens if the active substance Pariet gets to the fetus?
Pariet and pregnancy - how the drug in pregnant women
Unfortunately, the answer to this question, no one can, because the clinical trials of the drug in pregnant women were not conducted. However, laboratory studies were carried out of the drug in animals (rats and rabbits). These studies did not reveal any adverse effects Pariet during pregnancy, including the fetus.
However, the same study showed that rats pariet small amounts crosses the placental barrier, and thus obtained and the fetus. How it will react to this drug is the body of the pregnant woman and the fetus is unknown.
It is unlikely that these effects will be fatal, however, the body of a pregnant woman can be quite unpredictable respond to certain drugs. Given that Pariet have side effects, the manufacturer (the international pharmaceutical concern Janssen) does not recommend using it during pregnancy.
Therapeutic effects Pariet and its spillover effects on the digestive organs
Pariet inhibits acid secretion by cells of the gastric mucosa, gastric juice so significantly and rapidly reduced. On the one hand, this effect could play a positive role during pregnancy, as one of the most common complaints of women in this state, is heartburn.
But this is only at first glance. The fact that pregnant women digestive disorders associated with the suppression of the motor activity of the intestine progesterone
Progesterone - norm and pathology
and compression of the gastrointestinal tract growing uterus. If these violations will join another and insufficient gastric secretion, digestion will be much more difficult.
Besides the main therapeutic effect pariet and has spillover effects on the organs of the gastrointestinal tract. This effect manifests itself in the form of nausea, vomiting, diarrhea or constipation, dry mouth, abdominal distention, abdominal pain, appetite suppressants. And as a pregnant woman of the gastrointestinal tract, and so broken, all the side effects can only increase.
Risk of side effects and are of the liver - while taking Pariet may cause transient liver dysfunction, which in healthy people can be manifested only in the form of changes in laboratory parameters. But during pregnancy, liver and kidneys are working women with a double burden - need to neutralize and excrete double the amount of harmful metabolic products. Therefore, it is possible that the liver of the pregnant woman would react to the use of Pariet more strongly - how, nobody knows. Rather, these effects will be individual - most women pariet not harm, but some who have inherited some features of the structure and function of the liver, and can do much harm.
On the central nervous system pariet can also have side effects, which manifests itself in the form of general weakness, malaise, headache, dizziness, drowsiness or insomnia. All these symptoms may be so worried and pregnant women, and Pariet only aggravate the situation.
Dangerous for pregnant women can be a side effect exerted Pariet
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on the organs of blood, - decrease of blood platelets and white blood cells, particularly grainy. Platelets play an important role in blood coagulation system and the reduction of their content is fraught with bleeding disorders, which is very dangerous during pregnancy. No less important role played by the white blood cells - they protect the body from infections, while reducing their number may be reduced and the immune system. And during pregnancy, and so there is a natural decline in immunity (it is necessary that the mother's body does not reject foreign tissues of the fetus). Even more reduced immunity under the influence of Pariet lead to the development of infections.
In addition, when receiving Pariet possible development of allergic reactions, the occurrence of back pain, joint and muscle pain, flu-like syndrome, weight gain, depression
Depression - a little more than a bad mood
, Blurred vision and taste, stomatitis, increased sweating.
Thus, despite the fact that pariet well tolerated, it should not be used during pregnancy.