Dexamethasone was used in ampoules for intravenous and intramuscular administration, but also for introducing the solution into sites of inflammation or allergy (e.g., joints). Apply a dexamethasone dosage form for the relief of severe allergic reactions and to treat serious diseases when other methods are ineffective.
Action dexamethasone in ampoules for severe allergic reactions
For parenteral (bypassing the gastrointestinal tract) dexamethasone he immediately enters the bloodstream and starts to act. Therefore, it is most often used for severe allergic reactions.
When subcutaneous tissue swelling (angioedema), when the swelling goes to the area of the larynx and blocks airways, dexamethasone causes very rapid elimination of edema and the appearance of free breathing of the patient.
If anaphylactic shock under the influence of dexamethasone activated adrenaline, which causes an instant rise in blood pressure (BP) - the patient regains consciousness in the process of a slow injection into a vein.
Action dexamethasone in ampoules for severe allergic diseases
Dexamethasone in ampoules has a pronounced anti-allergic, anti protivoekssudativnoe and action.
This property is used for severe allergic diseases, where the use of other methods of treatment do not provide the desired action.
It is used for severe asthma, bronchospasm, when one follows the other - a condition called status asthmaticus. Often bring the patient out of status asthmaticus is impossible even with the use of inhaled corticosteroids. In such cases, the assigned short courses of dexamethasone, which initially may be administered by injection, then in a dosage form for oral administration. Short courses of hormone therapy generally does not have significant side effects.
Perhaps the use of injections of dexamethasone and allergic skin diseases such as atopic dermatitis in children and adults with eczema, as well as in allergic rhinitis.
Action dexamethasone in ampoules for severe infectious-allergic diseases
Such diseases include, primarily, rheumatoid arthritis
Arthritis - a variety of forms and complications
- Disease of the joints, which begins with an infection and takes a very long time, supported by an allergic reaction to the infection and the body's own tissues. An analogue of this disease is ankylosing spondylitis, which affects the spine.
At the same time, patients are suffering from inflammation, pain and dysfunction of joints. Sometimes the pain becomes so unbearable that they help remove only a short course of dexamethasone. Including desametazon inserted into the cavity of the joints.
Another infectious and allergic diseases, which often is assigned to dexamethasone, a glomerulonephritis. The main risk of glomerulonephritis is a rapid and significant renal dysfunction. Dexamethasone is in this case not only reduces swelling and inflammation of kidney tissue, but also inhibits the proliferation of connective tissue in it, which replaces the renal tissue, disrupting its function.
When dexamethasone is contraindicated
Dexamethasone - one of the most effective glucocorticosteroids
introduced by emergency indications for the salvation of the patient's life, the only contraindication to its destination is a hypersensitivity of the patient to the drug.
When administered dexamethasone therapeutic purposes courses contraindications for its use are taken into account, since this drug for its high efficiency can have many side effects.
Contraindication for administration of dexamethasone are erosive and ulcerative lesions of the gastrointestinal tract, diabetes
Diabetes - threatening and incurable disease
, Osteoporosis, Cushing's disease, purulent bacterial, viral or fungal infections, severe diseases of the cardiovascular system and thyroid, liver and kidney failure, immunodeficiency (eg HIV), a condition before or after vaccination, breast-feeding
Breastfeeding - a personal choice
Dexamethasone was administered with caution to children because it can cause them to breach the growth and sexual development. The same caution should be administered dexamethasone during pregnancy, as it may interfere with the development of the fetus, and late pregnancy inhibit the function of the adrenal glands, which would require replacement therapy after birth.
Dexamethasone in ampoules has a very fast and powerful effects on the body, so its application requires special care.