The active ingredient in the composition Ataraxum - hydroxyzine is Pharmaceuticals from the group of sedative antihistamines. Histamine is called a natural substance, which is part of the development of the body's reaction to potentially harmful substances penetrating from the outside. Histamine is stored in mast cells of most of the body tissue.

When a permeant into the body, the immune system identifies as dangerous (allergen) due to stimulation of mast cells release histamine, which binds to the H1-histamine receptors. At this point in the body runs many chemical reactions, visible and tangible result of which - the symptoms of allergies.

How does Atarax?

Hydroxyzine blocks the activity of histamine receptor penetrates into the brain, but it causes severe drowsiness. Because of this effect, it is recommended to take before bedtime Dreams: how to understand our dreams   Patients who are concerned about allergic itching at night. So often in children - the day they are constantly busy with something and just do not notice the itching, and at night unpleasant symptom makes itself felt.

Atarax is sometimes used for short-term treatment of increased anxiety Anxiety - how to distinguish normal from disease?   in adults. It inhibits the activity of certain parts of the central nervous system, and the patient becomes quieter.

pay attention

Because atarax sedation during treatment very best to give up driving and activities associated with an increased risk for the patient and other people. If the patient's work is directly related to the management of vehicles, Atarax does not suit you.

While receiving the drug should refrain from drinking alcohol.

Contraindications while taking Atarax

Atarax is necessary especially with caution and only when reasonably necessary to use children and the elderly, patients with impaired liver and kidney function, patients who undergo dialysis Dialysis - maintains normal body   kidneys; suffering from obstruction or decreased activity of the intestine; people with diseases such as epilepsy, dementia, glaucoma Glaucoma - a perspective possible blindness   and arrhythmia.

Atarax is contraindicated in children under six months, pregnant and lactating women suffering from porphyria.

Side effects

In atarax there are side effects such as drowsiness, dry mouth, dizziness, muscle weakness, headaches, difficulty urinating, constipation, ghosting visible objects, nausea and vomiting, insomnia, increased heart rate (tachycardia), tremor of limbs, convulsions.

Symptoms such as dizziness, double vision visible objects, muscle weakness, and others, can become even stronger if while taking Atarax drinking alcohol, as well as the following drugs:

• Antipsychotic drugs, such as chlorpromazine, haloperidol
• Barbiturates such as phenobarbital and amobarbital
• Benzodiazepines such as diazepam and temazepam
• Chlorphenamine, promethazine and other antihistamines with a sedative effect
• Sleeping pills, such as zopiclone
• Strong opioid analgesics - morphine, codeine, dihydrocodeine and other
• Tricyclic antidepressants, e.g., amitrptilin

To avoid constipation, dry mouth, and difficulty urinating, avoid taking Atarax at the same time the following drugs:

• Anticholinergic medications used to treat the symptom of Parkinson's disease
• Anticholinergic medications against urinary incontinence, such as oxybutynin and tolterodine
• Hlorpromazi, clozapine and other psychotic drugs
• Antispasmodics, such as hyoscine, atropine
• MAO inhibitors - phenelzine and others

Dexamethasone was used in ampoules for intravenous and intramuscular administration, but also for introducing the solution into sites of inflammation or allergy (e.g., joints). Apply a dexamethasone dosage form for the relief of severe allergic reactions and to treat serious diseases when other methods are ineffective.

Action dexamethasone in ampoules for severe allergic reactions

For parenteral (bypassing the gastrointestinal tract) dexamethasone he immediately enters the bloodstream and starts to act. Therefore, it is most often used for severe allergic reactions.

When subcutaneous tissue swelling (angioedema), when the swelling goes to the area of ​​the larynx and blocks airways, dexamethasone causes very rapid elimination of edema and the appearance of free breathing of the patient.

If anaphylactic shock under the influence of dexamethasone activated adrenaline, which causes an instant rise in blood pressure (BP) - the patient regains consciousness in the process of a slow injection into a vein.

Action dexamethasone in ampoules for severe allergic diseases

This property is used for severe allergic diseases, where the use of other methods of treatment do not provide the desired action.

It is used for severe asthma, bronchospasm, when one follows the other - a condition called status asthmaticus. Often bring the patient out of status asthmaticus is impossible even with the use of inhaled corticosteroids. In such cases, the assigned short courses of dexamethasone, which initially may be administered by injection, then in a dosage form for oral administration. Short courses of hormone therapy generally does not have significant side effects.

Perhaps the use of injections of dexamethasone and allergic skin diseases such as atopic dermatitis in children and adults with eczema, as well as in allergic rhinitis.

Action dexamethasone in ampoules for severe infectious-allergic diseases

Such diseases include, primarily, rheumatoid arthritis Arthritis - a variety of forms and complications   - Disease of the joints, which begins with an infection and takes a very long time, supported by an allergic reaction to the infection and the body's own tissues. An analogue of this disease is ankylosing spondylitis, which affects the spine.

At the same time, patients are suffering from inflammation, pain and dysfunction of joints. Sometimes the pain becomes so unbearable that they help remove only a short course of dexamethasone. Including desametazon inserted into the cavity of the joints.

Another infectious and allergic diseases, which often is assigned to dexamethasone, a glomerulonephritis. The main risk of glomerulonephritis is a rapid and significant renal dysfunction. Dexamethasone is in this case not only reduces swelling and inflammation of kidney tissue, but also inhibits the proliferation of connective tissue in it, which replaces the renal tissue, disrupting its function.

When dexamethasone is contraindicated

When administered dexamethasone therapeutic purposes courses contraindications for its use are taken into account, since this drug for its high efficiency can have many side effects.

Contraindication for administration of dexamethasone are erosive and ulcerative lesions of the gastrointestinal tract, diabetes Diabetes - threatening and incurable disease , Osteoporosis, Cushing's disease, purulent bacterial, viral or fungal infections, severe diseases of the cardiovascular system and thyroid, liver and kidney failure, immunodeficiency (eg HIV), a condition before or after vaccination, breast-feeding Breastfeeding - a personal choice   feeding.

Dexamethasone was administered with caution to children because it can cause them to breach the growth and sexual development. The same caution should be administered dexamethasone during pregnancy, as it may interfere with the development of the fetus, and late pregnancy inhibit the function of the adrenal glands, which would require replacement therapy after birth.

Dexamethasone in ampoules has a very fast and powerful effects on the body, so its application requires special care.

Galina Romanenko