Clotrimazole ointment used mainly for skin fungal diseases, which are accompanied by increased dryness of the skin. Unlike clotrimazole cream, which has a drying effect, an ointment base having fatty contrast, keeps skin moist.
Clotrimazole cream - how it works
The ointment for external USAGE clotrimazole includes active substance - with clotrimazole antifungal and adjuvants - emulsifying wax, cetostearyl alcohol, monoglycerides, polysorbate 80, propylene glycol, glycerol, castor oil, methyl parahydroxybenzoate, propyl parahydroxybenzoate and purified water.
After application to the affected skin ointment covers it with a protective layer, not allowing the moisture to evaporate from the skin. Simultaneously active substance ointment penetrates the surface and middle layers of the skin, providing anti-fungal and antibacterial properties. The blood of clotrimazole is practically not absorbed and has no general (systemic) effects on the human body.
In the surface layer of the skin (epithelium) produced very high concentrations of clotrimazole, much more than is required to kill the infectious agent. The concentration in the deep layers of the epidermis is higher than the minimum inhibitory concentration for dermatophytes - agents microsporia trihofitii and athlete - fungal infections are difficult to treat. Penetrating into fungal cells, clotrimazole inhibits the formation of membranes required for substances and this leads to disruption first permeability, and then to death.
Simultaneously, the high concentrations of clotrimazole penetrates into fungal cells and interacts with intracellular enzymes - this leads to the formation of cells in large amounts of hydrogen peroxide having a toxic effect. This further enhances the antifungal effect of clotrimazole.
Sensitivity to clotrimazole exhibit many fungi that cause infections in humans, including dermatophytes (causing microspores trichophytosis and athlete), yeast fungi genus Candida, pathogens scaly (colored) stripping and erythrasma.
To prescribe ointment clotrimazole
Clotrimazole ointment prescribed for fungal and bacterial, fungal skin infections of the skin caused by organisms susceptible to clotrimazole, and accompanied by increased skin dryness. This is a fungal disease of the skin caused by dermatophytes such as microsporia trichophytosis and smooth skin, jock itch
Jock itch: fungal infection
. These diseases are accompanied by increased dryness and flaking of the skin.
Candidiasis smooth skin also sometimes accompanied by dryness and flaking - in this case, to treat them well suited clotrimazole.
Clotrimazole ointment prescribed for pityriasis versicolor and erythrasma, which are also accompanied by dryness and peeling of the skin, as well as mixed bacterial and fungal infections.
Clotrimazole ointment applied thinly to the cleaned using soap with neutral pH and dry skin and gently rub. The procedure is performed two - three times a day. The duration of treatment depends on the diagnosis: the ringworm and candidiasis smooth skin it lasts four weeks, with pityriasis versicolor - from one to three weeks. When the foot fungus treatment is recommended to complete disappearance of all symptoms of disease and after another four weeks.
Clotrimazole ointment should not be used if you are hypersensitive to its components, and the body of the patient in the first trimester of pregnancy. It is not necessary to use the ointment in the weeping and inflammatory processes - in this case it is better to use clotrimazole cream - it has a drying effect.
Precautions clotrimazole ointment applied to the remaining stages of pregnancy, during feeding baby
Breastfeeding - a personal choice
feeding (ointment applied to the skin of the mammary glands during lactation can not), as well as abnormal liver function.
Clotrimazole ointment was well tolerated, but can sometimes cause side effects such as irritation, itching and burning of the skin. In some cases, appear on the skin edema
Prevention and treatment of edema - it is important to understand the root cause
, Redness, peeling skin and impaired sensitivity. In this case, the decision to continue or discontinue treatment takes a doctor.
If the skin around the affected area after applying the ointment appeared urticaria (a sign of an allergic reaction), you should immediately discontinue treatment.
Ointment clotrimazole effectively help in the treatment of fungal infections
Fungal infection: to prevent and defeat
Accompanied by dryness and flaking of the skin.