Guttate psoriasis occurs mostly in children and adolescents. In the development of this form of psoriasis is of particular importance streptococcal infection - a disease often begins after a postponed angina or purulent otitis
Purulent otitis - why develop complications
. Therefore, prevention of guttate psoriasis is of great importance sanitation foci of infection.
Why start guttate psoriasis
Guttate psoriasis is the same reason as the other forms of the disease - family history, disorders of cell metabolism and the breakdown of immunity. There are trigger factors that contribute to its development. Unlike other forms of psoriasis guttate psoriasis trigger factor in many cases is a bacterial infection, usually strep, at least - strep. But sometimes disease develops after viral infections. Guttate psoriasis develops within two to three weeks after a streptococcal infection - sore throat, otitis
Otitis - than could face an ear infection
, Sinusitis and so on.
It was found that the streptococci and staphylococci secrete large amounts of toxins, which play the role of antigens capable of binding to human tissue proteins. The molecules of the protein are located mainly on the skin cells (keratinocytes), the T-lymphocytes and monocytes. Such alterations in T leukocytes can lead to release of cytokines, stimulating the multiplication (proliferation) keratinocytes. Additionally, antigens associated with tissue proteins, antibodies are produced that leads to development of autoimmune process - allergic inflammation.
Therefore, prevention of guttate psoriasis is of great importance the timely recovery of the child - rehabilitation of foci of infection. This is especially significant for children and adolescents in families where there are people with psoriasis. Matter and other predisposing factors: stress, endocrine disorders, hormonal disorders, intoxication, chronic diseases and so on.
How does guttate psoriasis
Disease begins acutely in two to three weeks after infection. On the skin of the limbs and trunk there are small teardrop-shaped red papules with scaly surface. Most of these elements on the skin of the limbs and less often on the face (in most cases, the face does not happen rash). At the site of the rash may be formed in the injury of small erosions and ulcers that during exacerbation of the infection may increase in size.
The disease gradually becomes subacute and chronic when exacerbation followed by periods of partial remission. The disease sometimes runs alone during adolescence. But most of it goes to other, more specific to adult forms of psoriasis (vulgaris, exudative, and so on).
Treatment
Treatment of guttate psoriasis begin with the appointment of a diet: exclusion from the diet of fatty roasted meat, sweets, baking, soft drinks, chocolate, strong coffee and tea, hot spices, savory dishes. The child or adolescent should be fully fed, getting enough protein (lean meat, fish, dairy products), fats (preferred vegetable fats and butter) and carbohydrates (vegetables, fruits, cereals - a source of complex carbohydrates, vitamins, macro- and trace elements).
With a significant aggravation when disturbed general condition of the patient, or when frequent exacerbations administered cleansing the blood of toxic products through plasmapheresis. The positive effects and has enterosorption (purgation) through various enterosorbents.
When newly diagnosed guttate psoriasis, if confirmed by his association with staphylococcal infections, staphylococcal vaccine administered. Be sure to designate a complex of vitamins: vitamins B, C, D, A, E, D.
It is used as a new method of physical therapy - PUVA therapy (photochemotherapy) - long-wave radiation of the skin with ultraviolet rays with advanced drug administration, enhancing the photosensitivity of the skin.
To suppress the proliferation of the epithelium of the skin surface cells administered retinoids - drugs based activated vitamin A (e.g., neotigazon).
When mild form guttate psoriasis treatment begins with drugs for external use - ointments, creams, gels, lotions. During the advanced stage of the disease prescribe ointments, which include corticosteroids (such as triderm
Triderm - care for skin diseases
, Diprosalik, Elokim
Elokim - relieve inflammation and itching
, Advantan.
The stationary and regressing stages ointments containing derivatives of vitamin D3 (calcitriol) - Dayvoneks, Psorkutan and others who actively suppress the proliferation of skin cells.
Treatment of guttate psoriasis is held under the supervision of a physician, with no less importance is given to the prevention of exacerbations, which is the rehabilitation of foci of infection.
Galina Romanenko