Pancreas - is an elongated organ located in the abdomen between the stomach and the spine. It consists of the glandular tissue and ductal system. The main pancreatic duct extends along its entire length - it outputs pancreatic juice into the duodenum.
The pancreas has both endocrine and exocrine glands. That portion of the gland which performs endocrine functions, consists of about one million cluster of cells called the islets of Langerhans. These islets are composed of four cell types. Alpha cells produce glyukanon (and increase the level of glucose in the blood), beta-cells are responsible for the secretion of insulin (reduced blood glucose), gamma-cells produce somatostatin which regulates the activity of alpha- and beta-cells and PP-cells secrete pancreatic polypeptide .
As part of the exocrine pancreas helps the digestive system. It secretes pancreatic fluid, which contains digestive enzymes necessary for digestion of food.
Pancreatic diseases
- Diabetes first type. This violation of the immune system destroys cells in the pancreas responsible for insulin production. To control the level of glucose
Glucose: The energy source
To a patient in need lifelong insulin injections.
- Type II diabetes. The pancreas loses its ability to properly produce and secrete insulin. Develops insulin resistance
Insulin resistance - as it is dangerous for the body?
Which leads to an increase in blood glucose levels.
- Cystic fibrosis - a genetic disorder that affects many systems and organs, including the pancreas.
- Pancreas cancer. The pancreas consists of different types of cells, and all of them may begin to develop tumors of various types. In most cases, cancer cells begin to develop in forming shell main pancreatic duct. Pancreatic cancer is rare and the symptoms usually observed at the later stages.
- Pancreatitis - inflammation and damage to the pancreas by the impact of digestive enzymes that she generates.
- Islet cell tumor formed by abnormal propagation of islet cells. The tumor may be either malignant or benign. These tumors often leads to increased levels of hormones of the pancreas.
- Increasing the pancreas is not always pathological, but in some cases require treatment.
Diabetes is today - an incurable disease in which the blood is too high amount of glucose (sugar). Diabetes is the result of the fact that the body is not able to properly metabolize glucose, or because of a lack of the hormone insulin or because the body's resistance to its action. Full name "diabetes mellitus" comes from a Greek word that means "flowing", "going through something", and from the Latin «mellitus» - «Honey" or "Sweet". The fact that an excess of sugar in this disease is determined not only in blood, but is also found in the urine, resulting in diabetes XVII century was known as "write bad."
Diabetes was discovered more than 3, 5 th. Years ago. More than ¾ of patients suffer from a so-called type 2 diabetes type. Formerly known as the disease insulin dependent diabetes mellitus
Diabetes - threatening and incurable disease
. The rest of the diabetes type 1 - insulin-dependent diabetes mellitus.
What is the difference?
In diabetes type 1 in the body stops insulin production. Typically, the disease occurs in childhood or young age. As treatment prescribed diet and insulin injections.
In diabetes type 2 insulin is produced in insufficient quantities, or insulin-producing is not digested properly. This disease occurs in old age, and typically occurs after 40 years.
How is the level of blood sugar
In humans there is a transformation of glucose originating from the meal into energy for cells. Glucose in finished form contained in sweets - for example, in sweets or cakes - or is the result of digestion of foods containing starch - potatoes, pasta and bread. Also, the glucose produced by the liver.
In a healthy human insulin produced by cells of the pancreas gradually regulates blood glucose levels. Postprandial blood glucose level increases dramatically, while at the same time, insulin production begins. When the level of glucose in the blood drops - for example, by exercise - insulin also declines.
Another hormone produced by the pancreas is glucagon. It is, if necessary, to the liver, and thus there is a realization of glucose reserves, which in turn increases the level of glucose in the blood.
Insulin is produced and stored in the pancreas organ lobular, 15 cm long, is placed transversely in the retroperitoneum. It is often described as the two bodies in one, after it was discovered that the addition of insulin
The principles of action of insulin - the science of saving lives
The pancreas secretes enzymes that are essential for digestion.
Among those lipase, which promotes the absorption of fats, and amylase, which promotes the absorption of carbohydrates. Also, the pancreas produces sodium bicarbonate to neutralize the excess acidity in the stomach, which is able to damage the structure of the intestinal wall.