Kvamatel - a drug that has anti-ulcer action as suppresses gastric acid secretion. It is widely used for stomach ulcers and duodenal ulcers, as well as some other diseases of the digestive system.
As kvamatel acts on the stomach
Peptic ulcer and duodenal ulcer develops under the influence of increased acidity of gastric juice. A large amount of hydrochloric acid in gastric juice causes gastritis, esophagitis (inflammation of the esophagus that occurs due to the abandonment into the esophagus acidic stomach contents), duodenitis (inflammation of the duodenum), and a negative impact on the state of the liver and pancreas
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It stimulates the secretion of gastric juice, including hydrochloric acid, a biologically active substance histamine: on the surface of secreting cells of the stomach have molecules - receptors, having an affinity for the histamine called H2 histamine receptors (H1 receptors are located in the bronchi and blood vessels and are responsible for the development of allergic reactions).
In order to prevent the increased secretion of gastric acid, drugs are used, which are called histamine H2-receptor blockers. One such drug is kvamatel.
Kvamatel peculiarity is that it not only blocks histamine H2 receptors, but also has an active effect on gastric mucus, increasing its number and its content of different protective substances. Such protective substances are, e.g., prostaglandins, which are always contained in the gastric mucosa and protect it from any external influences. For example, when administration of nonsteroidal anti-inflammatory drugs (NSAIDs, such as diclofenac) inhibited the activity of prostaglandins, which could lead to the formation of stomach ulcers. Prostaglandins also promote rapid scarring.
This shows the use of
Apply kvamatel only on prescription after a preliminary examination, and further diagnosis. The main indication for the use of this drug is a gastric ulcer and duodenal ulcer. This eliminates the annoying kvamatel mucosa factor that increases its defense and promotes rapid scarring ulcers. It will kvamalel and erosive and ulcerative lesions of the stomach and duodenum caused by stress and NSAIDS.
In some cases, ulceration of the gastric mucosa yet, but inflammation in the stomach irritation constantly maintained its walls gastric juice acidity. This disease is called giperatsidnym gastritis and also requires the suppression of gastric acid secretion.
The acidic contents of the stomach may be bombarded with the esophagus, causing irritation of its walls (reflux esophagitis). May enter the gastric juice into the duodenum, causing its damage, and inflammation. In all these cases kvamatel will bring significant relief to patients.
The stomach and duodenum may suffer and adenoma (a benign tumor of glandular tissue) of the pancreas. In the pancreatic juice contains a large amount of gastrin hormone which stimulates gastric acid secretion. As a result, developing Zollinger-Ellison syndrome - ulcerative lesion of the gastric mucosa and duodenal ulcers. Kvamatel prevents the development of this syndrome.
Finally, kvamatel prescribed as part of a complex of anti-treatment for the prevention of any exacerbation of digestive diseases associated with increased gastric secretion. Cancel kvamatel gradually, as the sudden interruption of its reception may develop withdrawal symptoms.
When kvamalel contraindicated, and whether he has side effects
Kvamatel has few contraindications. It can not be used during pregnancy and nursing
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feeding, in children and patients are hypersensitive to the components of the drug. Precautions kvamatel prescribed for severe liver and kidney diseases in violation of their functions.
Kvamatel has a number of side effects that occur relatively seldom, however, need to know about them. This loss of appetite, dry mouth, nausea, vomiting, stomach pain, bloating, constipation, diarrhea, transient liver dysfunction, acute pancreatitis. Changes in the blood can cause a decrease in immunity and the threat of bleeding, and on the part of the cardiovascular system - heart rate arrhythmia, cardiac blockade and reduction in blood pressure. May worry as headache, dizziness, lethargy, drowsiness, hallucinations, confusion, decreased vision and hearing, hormonal disorders (male of female type changes in women - menstrual disorders), pain in joints
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and muscles, acne
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, Alopecia, allergic reactions.
Kvamatel - quality medicines, which produces well-known pharmaceutical company Gedeon Richter (Hungary).