- Medications to reduce blood pressure - the means employed
- Inhibitors and Blockers
Angiotensin-converting enzyme (ACE)
These drugs prevent the production of a hormone called angiotensin II, by blocking the production of angiotensin converting enzyme, which performs a variety of functions.
The body has several ways to control blood pressure, but among them there are two main elements. One of them - is resistance of the blood vessels. When blood vessels constrict, the resistance increases, and when expanded (as their walls, respectively, relax), it is reduced. Provided that the circulatory system always moves the same volume of liquid, the higher the resistance vessels, the higher is the blood pressure. The second of these elements - the volume of blood which the heart ejects each stroke in the vessels. Human blood pressure is dependent on these two factors, ACE inhibitors affect both factors. They constrict blood vessels and affect the resorption of fluid (which determines the volume of blood).
ACE inhibitors include drugs such as benazepril hydrochloride, captopril, enalapril maleate, fosinopril sodium, lisinopril, moexipril, perindopril, ramipril, trandolapril.
Some of the possible side effects of ACE inhibitors - skin rash, decreased sensitivity to tastes, chronic dry cough
Dry cough - whether to worry about it?
In rare cases - liver damage.
Angiotensin 2 receptor blockers (ARBs)
Angiotensin 2 receptor blockers (ARBs) block the activity of angiotensin 2 - substances under the influence of which the blood vessels are narrowed. To have such an effect, angiotensin receptor should connect. ARB blocking these receptors, preventing vasoconstriction. For drugs in this class include, for example, candesartan, irbesartan, telmisartan, valsartan.
The most common side effects of these drugs are headache, dizziness, nausea, nasal congestion, pain in the back or feet, diarrhea.
In rare cases, receiving ARBs can cause serious side effects such as kidney failure
Kidney failure - when treatment is vital
, Liver failure, severe allergic reactions, reduction of white blood cells, swelling.
ARBs should not be taken during pregnancy. These drugs can cause severe malformation of the fetus and even death. If you become pregnant during treatment, stop taking the drug and contact your doctor immediately.
Calcium channel blockers
Our heart is composed mainly of the specific muscle cells, which contract, forcing blood into the arteries. Such cells also exist in the walls of blood vessels. When they contract, the arteries are narrowed, and the pressure inside the vessel increases. For these reductions the cells requires calcium, which comes into them through thin channels. Calcium channel blockers reduce the amount of calcium flowing into the cells, and thereby dilate blood vessels and lower blood pressure.
In the group of calcium channel blockers include amlodipine besylate, bepridil hydrochloride, diltiazem, felodipine, isradipine, nicardipine, nifedipine, nisoldipine.
Side effects of drugs of this type can be constipation, headaches, heart palpitations, dizziness, rash, fatigue, hot flashes, nausea, swelling of hands and foot.
Some calcium channel blockers may interact with the substances contained in grapefruit, juices of these fruits, and a variety of products based on them. If you are taking any of these drugs, and want to sit on the grapefruit diet or begin taking any supplements on the basis of a grapefruit, talk to your doctor.
Alpha-blockers or alpha blockers
These blockers relax the wall of certain muscle groups, thus maintaining normal blood pressure. Since they attack not only the muscles along the blood vessel, but also to other muscles, these drugs are also used in case of problems with urination in elderly people with a variety of diseases of the prostate.
Alpha-blockers include, for example, doxazosin mesylate, prazosin hydrochloride, terazosin hydrochloride.
At the beginning of treatment in many patients after administration of alpha-blockers appear symptoms such as a dramatic drop in blood pressure, dizziness
Dizziness - if the ground is slipping from under his feet
and sometimes fainting. For this reason the first dose is recommended to take before bedtime
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. When the body gets used to the drug, these side effects disappear. Other possible side effects of beta-blockers - headaches, nausea, weakness, weight gain.