Lamisil spray - is an antifungal drug for topical application to the dried and refreshing effect. This feature allows you to use it in any clinical manifestations of fungal infection. But it is especially suitable Lamisil spray in the case where the lesions are located in remote areas and are accompanied by weeping skin.

Lamisil spray - how it works

Lamisil spray for topical use is a transparent colorless or light yellow liquid and available in vials as a 1% solution. The composition includes a spray Lamisil terbinafine active substance and excipients: Macrogol cetostearyl ether, ethyl alcohol, purified water, propylene glycol, nitrogen.

Lamisil Spray is used only externally and has an active antifungal activity. At the same time it is refreshing and dries the skin. When applying the spray to the skin is absorbed into the blood is not more than 5% of the active active ingredient, so significant systemic effects of the drug has not. Caught in the spray penetrates the skin to the surface layers of the skin and actively influences the metabolism Improves metabolism and losing weight without dieting   in fungal cells in the lesion.

The mechanism of action of the spray is no different from that of all other dosage forms lamizila. It suppresses the formation of sterols in fungi cells, resulting in their lack of normal metabolism in cells. Simultaneously, the fungal cells accumulate a large number of intermediate from which built the necessary cells sterols, - squalene. Such a violation of metabolic processes leading to fungal cell death.

Sensitivity to lamizilom Lamisil - a modern drug to help cope with fungal infection   exhibit many dermatophytes, cause fungal infections of the skin, as well as yeast fungi genus Candida, and the causative agent of colored (pityriasis) stripping.

The spray is effective, penetrating into the most remote areas of the affected skin, but it is inconceivable that he found himself in the eye - it will cause considerable irritation to the eye tissue.

In severe fungal infections external use spray combined with taking Lamisil tablets inside.

With which diseases and how to apply Lamisil

Features Spray Lamisil allow its use in many fungal infections (mycoses), including the athlete's foot (tinea and rubrofitii), jock itch Jock itch: fungal infection , Fungal infections of the skin smooth body, caused by dermatophytes with the defeat large folds of skin and located in hard to reach places. Applied Lamisil Spray for the treatment of fungal infections of the scalp.

Lamisil Spray is effective also in the chafing of the skin, caused by Candida - simultaneous antifungal and drying effect allows you to quickly remove these lesions.

In addition, spray Lamisil is used successfully for the treatment of multi-colored (pityriasis) stripping.

Apply spray only for the treatment of adults and children after 12 years. Before its application the skin carefully cleaned and slightly dried. Then spray applied in sufficient quantity so that the skin lesions and the areas located around the healthy skin areas was well-moistened.

Lamisil Spray is applied to the skin once a day for a week. With multi-colored shingles spray is applied twice a day in a week.

Side effects and contraindications

The side effects of Lamisil spray is rarely significant. The skin on the spot spraying lamizila may be signs of irritation in the form of redness, dryness and flaking of the skin accompanied by burning and itching.

There may be allergic reactions, which may be similar to conventional stimulation. Allergy is manifested as hives, prone to mergers, the defeat large areas of skin and subcutaneous tissue in the transition, including in the area of ​​the throat (angioedema). If there are signs of irritation or allergy, you need to see a doctor who will decide whether to continue treatment: during stimulation is often possible to continue it, and allergies should be stopped immediately.

Lamisil Spray is contraindicated in case of hypersensitivity to its components, and of the patient below the age of 12 years (clinical trials of the drug in children have not been conducted). With caution and only on prescription should be used during pregnancy, infant feeding Breastfeeding - a personal choice   breast, liver problems and kidney failure, chronic alcoholism, cancer (including blood diseases), metabolic disorders and diseases associated with impaired patency of the blood vessels of the limbs.

Lamisil Spray - very convenient dosage form for the treatment of fungal infections located in hard to reach areas of skin.

Galina Romanenko

Nolitsin - quinolone antibacterial drug, has a pronounced antimicrobial action, is most effective in diseases of the urinary organs. It is active against most pathogens of these infections, such as acute and chronic inflammatory diseases of the kidney and urinary tract infections, gonorrhea Gonorrhea - self-ruled .

The mechanism of action nolitsin

Nolitsin (INN - norfloxacin) - a broad spectrum antibiotic fluoroquinolone group, which is made of the Slovenian pharmaceutical company Krka tablets, eye and ear drops. Other pharmaceutical companies similar drugs sold under the name ankvin, baktinor, girablok, kvinoloks, lokson, negafloks, norbaktin, norilet, Normaks, noroksin, norfloks, norfloxacin, sofazin, spektrama, chibroksin, yutibid.

Nolitsin has bactericidal (kills sensitivity to bacterial flora) activity and is characterized in that to it practically tolerance develops (resistant) microorganisms. It inhibits the formation of certain necessary enzymes for life of bacteria (e.g., DNA gyrase), which leads to the impossibility of formation of DNA strands and the instant death of the bacteria. The bactericidal effect appears very quickly, within an hour after taking the drug.

Furthermore, nolitsin contains fluorine, which further enhances the activity of this drug against most bacteria sensitive to it. Also active influence on ordinary gram (mainly) and gram-positive (some of) the microflora, causing the majority of infections of the urinary tract, suppresses nolitsin livelihoods of Pseudomonas aeruginosa - one of the most stable in relation to antibiotic-resistant bacteria.

When administered nolitsin well absorbed from the gastrointestinal tract into the blood, and thence tissue (particularly tissue urinary organs) do not penetrate the central nervous system and bone. Absorption is slowed down meal (especially breast, so it is best to take on an empty stomach), and drugs that neutralize the acidity of gastric juices (antacids). The maximum concentration in blood is achieved within 1-2 hours after ingestion. Stored in the body 12 hours after which decomposes in the liver (its breakdown products - metabolites also possess some activity), and then excreted in urine (mostly) and feces. Therefore, when severe impaired renal function is recommended to install an individual dose.

Indications and contraindications for receiving nolitsin

Admission nolitsin into tablets is shown in the following diseases (only after laboratory tests of biological material on the sensitivity of microorganisms to the antibiotic)

• infections of the urinary tract - pyelonephritis, cystitis, urethritis (mostly nolitsin able to suppress any flora that can cause infections of the kidneys and urinary tract infections, including those resistant to other antibiotics);
• after surgical operations on the kidneys and urinary tract in order to prevent infection or acute exacerbation of chronic infections;
• gonococcal infections, including those with hidden, unexpressed over;
• intestinal infections - salmonellosis Salmonellosis - features of the disease , Dysentery, iersineoza;
• for the prevention of intestinal infections during visits in areas where these infections (it does not inhibit the normal intestinal microflora);
• infections of internal genital organs of men and women (chronic bacterial prostatitis Bacterial prostatitis - can be acute or chronic , Adnexitis - inflammation of the ovaries in women);
• infections of the skin and soft tissues, including wound infections, abrasions;
• infection of upper respiratory tract (sinuses, pharynx, larynx, middle ear);
• infections of view.

Local nolitsin used in eye and ear drops in infections of vision and hearing, as well as for prevention of these diseases.

Contraindications nolitsin are hypersensitivity to the drug, age 15 expressed by the human kidney. During pregnancy and lactation, the issue of use of the drug is solved individually for health reasons.

Side effects that may occur when applying nolitsin

In applying nolitsin may experience the following side effects:

• from the gastrointestinal tract - heartburn, loss of appetite, nausea, diarrhea, abdominal pain Abdominal pain: Types and Symptoms ;
• from the liver - a small abnormal liver function;
• the central nervous system - headache, dizziness, lethargy, loss of efficiency, sleep disturbances, irritability, anxiety;
• by the kidneys and urinary tract infections - inflammation of the connective bases kidneys (interstitial nephritis), renal failure;
• allergic reactions - skin rashes of various kinds, itching, swelling of the tissues.

The caution is recommended when nolitsin spasmophilia any origin, when expressed violations of the liver. While receiving the drug should not take dairy products, and be under the influence of sunlight. Not recommended as during the course of treatment nolitsin drive vehicles.

Nolitsin - is an antibiotic that can be taken only on prescription.

Galina Romanenko