Thrush - an infection that spares no one, neither women nor men, nor even children. Causes of thrush are very diverse and sometimes banal. It would seem, well, how to link the disease with malnutrition? Quite simply, lead to the development of thrush factors that contribute to the weakening of the immune system. Sometimes, identify the cause of thrush is hard enough, and therefore the treatment of the disease does not bring proper results. And why should begin treatment of thrush? With the elimination of the reasons that caused it. That is why doctors and patients need to know the causes of yeast infection.

What is thrush

Thrush - a disease which is caused by fungi of the genus Candida. That is the main cause of the disease are fungi. The infection affects the skin and mucous membranes of the body. The name "thrush" fungal infection was due to the characteristic features of urogenital candidiasis or vaginitis. This woman says abundant milky discharge with lumps, like curds. Women thrush often occurs in the form of a fungal vaginitis, men are usually affected glans penis (balanitis), and children usually develop fungi in the oral region, in severe cases, the affected skin of the face and the back wall of the pharynx.

Causes of thrush

Predisposing factors come into play in the case of weakening the body's defenses. Causes of yeast infections in women Thrush in women - the relevance of the problem   and men alike, while the children often have their "own" factors of the disease. The main causes of thrush Causes of yeast: what should be afraid of   - this:

• Infections, sexually transmitted infections

Infections which are transmitted sexually, such as chlamydia, ureaplasmosis Ureaplasmosis - inflammation of the urogenital system   Other, frequently occur latent (hidden), i.e. without any apparent clinical signs. However, they are harmful to the body, reducing its protective function. What is the trigger in the development of thrush.

• Hormonal disorders

Not the least role in immune disorders and play a natural hormones. They are on a par with the other components responsible for immunity. In the case of various endocrine diseases of the body undergoes hormonal imbalance, which can lead to thrush. Also here it can be attributed to hormonal contraception in which the production of its own hormones is suppressed.

• Gestation

It noted the frequent occurrence of yeast infection during pregnancy, especially in the last three months. Again, this is due to changes in hormonal levels. During pregnancy, increased levels of progesterone Progesterone - norm and pathology Which firstly, weakens the immune system of the woman, and secondly contributes to a strong acidification of the vaginal environment. These factors are favorable for the development of thrush.

• HIV infection

HIV is ranked first among the diseases that weaken the immune system. In fact, HIV is a chronic immunodeficiency. Against the background of this disease easily develops not only yeast, but other infectious and viral processes.

• Medication

Thrush develops while taking certain medications, such as antibiotics, steroids (dexamethasone, prednisolone) and cytostatics. The weakening of the body's defenses against the background of antibiotic therapy is associated with inhibition of the growth and development of not only pathogens but also normal. Cytostatics in turn inhibit the growth of cancer, and with them and normal body cells, which are involved in immunity.

• Errors in the diet

Lovers of sweets susceptible to fungal infections more often than other people. Furthermore, in the development of yeast plays a role as a change of climatic conditions, and chronic stress, which also weakens the immune system.

• Violation of personal hygiene

Failure to comply with the rules of personal hygiene also applies to one of the predisposing factors of occurrence of thrush. As too often caving, especially with soap, and their complete disregard for fungi helps to activate. Of particular importance is the underwear. Synthetic and tight underwear creates favorable conditions for the development of thrush.

Anna Sozinova

Orungal - is an antifungal drug broad spectrum. It effectively cope with the fungal infection, inhibiting the synthesis of biologically active substances that make up the cell membrane of fungi. Orungal of instruction is used to treat many diseases of the skin, nails and mucous membranes. Including used in fungal infections of internal organs.

The mechanism of action orungala

Orungal (active substance - itraconazole) - an antifungal drug broad spectrum of action, which makes the Belgian pharmaceutical company Janssen Pharmaceutica in the form of capsules and oral solution.

The mechanism of action of the drug associated with the suppression of the synthesis of ergosterol, a component of the cell walls (membranes) fungi, which leads to their death. To show the effects of the drug sensitivity of the pathogens of most fungal infections, causing diseases of skin, nails and mucous membranes, including in the field of internal organs. Most of yeast fungi of the genus Candida are also showing sensitivity to orungalu Orungal - antifungal broad spectrum , But some types are less sensitive to the drug. Not susceptible to pathogens orungalu only zygomycosis, fizarioza, skopulyariopsioza and alleshiroza.

If ingestion orungal well absorbed into the bloodstream and enters into all tissues. Displayed as metabolites and partially unchanged in the feces and urine. Isolation orungala from skin and nails is slower than from the blood, and therefore the therapeutic effect lasts a few weeks after the end of treatment of fungal infections of the skin, and six months after cessation of treatment of fungal nail infections.

Indications and contraindications

Orungal used in the following fungal infections caused by susceptible to the pathogens:

• candidiasis of the mucous membranes, including the oral thrush, genital candidiasis of view;
• fungal diseases of the skin, including the pityriasis versicolor;
• fungal nail infections;
• in systemic fungal infections - aspergillosis, candidiasis, cryptococcosis (including cryptococcal meningitis), histoplasmosis, sporotrichosis, paracoccidioidomycosis, blastomycosis;
• in other rare systemic or tropical fungal infections;
• as prophylaxis of systemic fungal infections in patients with cancer and lowered immunity.

At low acidity of gastric juice suction orungala broken, so such patients, it is desirable to take this drug with cola. The interval between administration of drugs which decrease gastric acidity and orungala must be at least two hours.

Contraindications for use orungala:

• increased sensitivity of the patient to the drug;
• Pregnancy and breast-feeding Breastfeeding - a personal choice   breast;
• can not be combined with the following reception orungala drugs: mizolastine, dofetilide, quinidine, pimozide, sertindole, Levo, cisapride - it can cause severe disorders of the cardiovascular system; with midazolam, triazole, simvastatin, lovastatin, and with preparations of ergot alkaloids (dihydroergotamine, ergometrine, ergotamine and metilergometrina).

Caution should be used orungal in the human liver, kidneys and cardiovascular system, children, elderly patients and patients who have had allergic reactions to other drugs in this group (fluconazole, ketoconazole, voriconazole, etc.).

Side effects orungala

In applying orungala can develop the following side effects:

• the part of the digestive system - nausea, vomiting, abdominal pain Abdominal pain: Types and Symptoms , Constipation, transient abnormal liver function, chronic hepatitis Hepatitis - the scourge of our time ;
• Nervous system - headache, dizziness, neuralgia, peripheral nerves;
• on the part of the cardiovascular system - heart failure, edema, lack of potassium in the blood;
• allergies - itchy allergic rash, urticaria, angioedema, hair loss, Stevens-Johnson syndrome (severe allergic lesions of the mucous membranes);
• on the part of the reproductive system - menstrual irregularities.

Overdose

Data on overdose orungala not. However, manufacturers recommend Accidental overdose within the first hour after ingestion gastric lavage and take a few pills of activated carbon.

Orungal - is an effective antifungal drug that is taken only on prescription.

Galina Romanenko