Nonsteroidal anti-inflammatory drugs (NSAIDs) are very popular because of the wide spread of severe and long proceeding diseases of joints and spine. Movalis - is an effective analgesic and anti-inflammatory drug with minimal side effects.

The first NSAID was aspirin, open more than one hundred years ago. At the time, he made a real revolution, as has analgesic, anti-inflammatory and antipyretic properties. After that was released a lot of drugs in this group. Their action was the fact that block the function of the enzyme cyclooxygenase (COX), which is involved in the formation of prostaglandins - biologically active substances that are required by the body at different levels. In particular prostaglandins are involved in the formation of inflammatory reactions. But, in addition, prostaglandins are involved in the protection of gastric mucosa from any actions, so by blocking the action of COX gastric mucosa often ulcerate.

Opening movalis

Over time it was found that cyclooxygenase is not uniform, it is divided into COX-1 - is responsible for the state of the gastric mucosa, and COX-2, which promotes the formation of prostaglandins in the inflammation. After much research was published the first drug that selectively (selectively) inhibited the activity of COX-2 (nimesulide) and no adverse effects on the gastrointestinal tract.

Movalis also is a selective inhibitor of COX-2, which minimized side effects. This drug is of good quality, mild action and few side effects.

Application movalis

The most common NSAIDs should apply to patients suffering from infectious and allergic diseases of the joints and spine, which occur mostly life. At the heart of these diseases is allergic to its own tissues and joints of the spine, combined with constantly maintain an inflammatory process in this area. Typically, such patients suffer greatly from pain and are therefore forced to take painkillers for life. Movalis is a suitable means for continuous use, as it is well tolerated and is stored permanently in the body, thus requiring only a single dose. In addition, as much the producer, the drug is hondroneytralnym, that is does not affect the cartilage, which is very important in diseases of the joints and spine.

Used movalis and degenerative diseases of the joints and spine - arthrosis and osteochondrosis, which are characterized by changes in the exchange character and also accompanied by pain.

Of course, movalis Movalis - relieve symptoms of inflammation   can shoot pain and other origin, such as toothache, headache, abdominal pain during menstruation and to reduce the temperature.

Side effects and contraindications

Yet, despite the fact that the drug is selectively inhibits COX-2 is partially inhibited and wherein the COX-1, since it is a single enzyme system. Therefore, the instructions for movalis faithfully lists all the possible side effects, even if they had never seen before.

So, certainly reminded that the drug should not be prescribed in the case of any acute erosive and ulcerative process in the gastrointestinal tract - it can lead to the development of gastric ulcers Gastric ulcer - such dangerous snacks   or duodenal ulcers, bleeding, perforation of the stomach wall or bowel.

Under no circumstances should also not be used in movalis if after taking any NSAID were bronhostpazma attacks - so-called "Aspirin asthma", these attacks may well happen again, and when taking any other medication.

Do not use movalis during pregnancy - it can lead to various defects of the fetus Fetal development - week after week And during breast Breastfeeding - a personal choice   feeding. There are limitations in the age up to 12 years for the tablets and suppositories, and up to 15 years for injection.

Not recommended intake movalis with severe kidney, liver and cardiovascular system, as in these diseases movalis and products of its metabolism can linger in the body.

Finally, movalis reduces the ability of blood to clot, and blood clots - the action is not very pronounced, however, is not recommended movalis a tendency to bleeding from any source and in disorders of blood clotting.

Yet, despite the large number of warnings, contraindications and side effects, movalis in most cases well tolerated and has a pronounced analgesic and anti-inflammatory effect.

Galina Romanenko

Infectious mononucleosis - a self-limiting infection, most commonly caused by the Epstein-Barr virus, or EBV, which is a human herpes virus fourth type. However, approximately 10% of cases of infectious mononucleosis is associated with cytomegalovirus. Infectious mononucleosis is most common among teenagers and children. The disease is usually transmitted by physical contact and / or contact with the saliva of an infected person.

Symptoms

Symptoms of infectious mononucleosis is often mistaken for symptoms of colds and flu. Among them:

• Fever
• A sore throat
• Inflammation of the lymph nodes (in the neck, groin and armpits)
• Weakness
• Headache
• Myalgia
• Enlarged liver and spleen
• Skin rash
• Abdominal pain

In adolescents and adults, the symptoms of infectious mononucleosis can be very soft, almost imperceptible. Children are usually significantly more severe symptoms; when they occur should consult a doctor. Usually the symptoms, even without treatment is 2-4 weeks, but some teens weakness and lethargy persisted for several months.

Treatment

If the patient is infectious mononucleosis Mononucleosis - forecast favorable   the child feels OK, he can continue to go to school. Adult patients with this disease is very rare and requiring hospital. Patients are advised to abandon the occupation grade for three weeks. This is due to the fact that in infectious mononucleosis there is an increased risk of rupture of the spleen; if you exercise it becomes even greater. During his illness should refrain from drinking alcohol. To relieve pain and fever are advised to take paracetamol; if it does not work, ask your doctor to advise you more powerful drugs.

In some cases, you may need a short course of corticosteroids. Other specific drugs for treatment of infectious mononucleosis usually not used.

In rare cases, spontaneous rupture of the spleen surgery is needed; often with this condition can be managed without surgery.

Complications

A significant increase in the tonsils in infectious mononucleosis can lead to upper airway obstruction. Myocardium and cardiac conduction are rare but possible complications of infectious mononucleosis. Rupture of the spleen is also rare, but is a potentially life-threatening. Splenectomy (surgery to remove the spleen), in turn, increases the likelihood of various infectious diseases. In addition, complications of infectious mononucleosis may include: hemolytic anemia, thrombocytopenia, acute interstitial nephritis, glomerulonephritis Glomerulonephritis - a severe infection of the kidneys , Optic neuritis, transverse myelitis, aseptic meningitis Meningitis - an inflammation of the meninges , Encephalitis, meningoencephalitis, cranial nerve palsies (especially common facial paralysis), Guillain-Barre syndrome, prolonged unfounded weakness, depression Depression - a little more than a bad mood .

Forecast

Infectious mononucleosis usually asymptomatic and / or passes quickly, even without treatment. The weakness and myalgia (muscle pain) may persist for several or even many months after the acute infection has been cured. For patients with ruptured spleen prognosis is favorable, provided that the treatment was started promptly. Chance of other serious complications is low; it increases if the patient has serious comorbidities.