Vilprafen like any other antibiotic systemic action, have a significant impact on the human body. In particular, vilprafen provides increased load on the liver cells, as it is in the liver is its decomposition products of metabolism with subsequent excretion from the body in the bile and feces. Alcohol also is a specific poison for the liver cells.

Action Wilprafen on the human body

Vilprafen - is a modern highly effective and non-toxic macrolide antibiotic. Active ingredient Wilprafen - Josamycin suppresses livelihoods, and at high doses kills pathogens. The mechanism of action Wilprafen associated with the suppression of protein synthesis in bacteria.

Available vilprafen Vilprafen - modern highly effective and non-toxic antibiotic   in dosage forms for oral administration. Its main feature is a fast and complete absorption in the duodenum, so it hardly misses the rest of the intestine and causes of dysbacteriosis. With bloodstream Josamycin spreads to organs and tissues, while in sites of inflammation is sometimes accumulates much higher than in blood.

Josamycin decomposed in the liver to less active metabolites (metabolites), and then excreted in the bile and faeces. Only a small portion of the drug is excreted in urine.

In most cases vilprafen no adverse effects on the liver. However, such side effects can not be eliminated - a large burden on the liver cells can cause significant malfunctions of the body. Most often this happens if the patient some violations of the liver congenital or acquired nature.

Manifest violation of such transient changes in liver enzymes, hepatitis, developed on the background of the intra- and extrahepatic bile stasis, which may manifest fever, jaundice, malaise, weakness. There are also a pain in the right hypochondrium, nausea, vomiting, diarrhea.

Most side effects are still evolving from the gastrointestinal tract. This stomach pain, nausea, vomiting and diarrhea, which speak of irritation of the mucous membrane of the stomach and duodenum.

The effect of alcohol on the human body

Alcohol has a negative effect on the function of all organs and systems. This alcohol is considered to be a specific poison for the cells of the liver and the brain. The systematic human consumption of alcohol liver disease can develop in different ways. It all depends on the individual, and heredity.

Many people have alcoholic liver disease goes unnoticed. Without any special sensations in liver cells initially disturbed metabolism Improves metabolism and losing weight without dieting   (steatosis or fatty liver) and then joins the inflammatory process, the liver cells are actively being destroyed (toxic alcoholic hepatitis). The last stage is the rapid growth of connective tissue in the liver that replaces dead liver cells (hepatocytes). It often happens that some start-up torque (heavy exercise, medication, has a toxic effect on the liver, and so on) has caused a serious condition in a person who had considered himself healthy.

Violations of the liver can be formed quickly, especially with congenital or acquired disorders of enzyme in the body. This leads to rapid formation of cirrhosis.

Irritation has alcohol and on the gastrointestinal tract, causing abdominal pain, nausea and vomiting.

What happens if you combine alcohol intake Wilprafen

The instructions to vilprafenu developed by the manufacturer, nothing is said about the negative effects of such a combination. But, for example, erythromycin Erythromycin - if you are allergic to penicillin   (First macrolide) may not be combined with alcohol - it may enhance absorption of alcohol in the stomach and intestine and increases its concentration in the blood - may alcohol poisoning.

But the biggest danger when taking Wilprafen with alcohol threatened by the liver: hepatotoxicity Wilprafen under the influence of alcohol repeated efforts. How it will end it depends on the patient's body: can nothing bad will happen, but most likely, the effects will still be as welcome Wilprafen combine alcohol drinkers are mostly people who have liver problems.

Efforts and symptoms of irritation of the gastrointestinal tract - abdominal pain Abdominal pain: Types and Symptoms , Nausea, vomiting and diarrhea.

But even if there are no serious consequences of not, the effectiveness of treatment vilprafenom while alcohol consumption will decrease.

Galina Romanenko

Dimexidum has antibacterial, anti-inflammatory and analgesic effect. It belongs to the drugs, which are used only externally. Nevertheless, it is actively penetrates through the skin and mucous membranes in the blood and may cause the overall impact on the body. That's why he has a lot of contraindications for use.

What's dimexide drug and how it works

Active ingredient Dimexidum is dimethyl sulfoxide, which is different pharmaceutical companies sold under the name DMSO brosorb, damul, deltan, demasorb, demavet, dermasorb, dolikur, dromisol, Mastan and others.

Dimexide Available in bottles of 100 ml and is a colorless, clear liquid with a specific smell, which is perfectly miscible with water in any ratio.

Dimexidum can very easily penetrate through biological membranes, including the skin and mucous membranes and therefore even if the external application can provide a general effect on the body. Penetrating deep into the tissue, dimexide has anti-inflammatory, antimicrobial and mild local anesthetic effect. In addition, it can dissolve clots in the blood vessels formed by thrombophlebitis.

Dimexidum also able to improve the metabolic processes in the cells of the skin and mucous membranes by inhibiting the activity of free radicals. This property has made an essential drug for the treatment of focal baldness in adults.

Which diseases apply dimexide

The most widely used dimexide found in various diseases of the skin and soft tissues. It is used in the treatment of Alopecia areata in adults, in this case, the improvement of metabolic processes in the cells of the scalp leads to improvement of hair roots and their growth. This medication is used to treat burns and eczema - it helps to reduce inflammation and prevents ingress to burns and weeping surface of the skin with eczema infection.

Improving the metabolic processes in the skin help to improve the flow of systemic connective tissue diseases such as scleroderma Scleroderma - affects all the organs .

When pustular skin diseases, including the youthful acne, abrasions and so on, improvement comes through anti-inflammatory and antimicrobial action Dimexidum. All properties Dimexidum necessary in order to restore the integrity of the skin with festering wounds and trophic ulcers.

When thrombophlebitis of superficial veins dimexide promotes the resorption of blood clots and restore the health of vein walls.

Widespread use dimexide found in diseases of the joints and spine, both inflammatory and degenerative. When applied topically, it is perfectly removes inflammation and pain. By restore metabolic processes in the joint is partially contributed to the restoration of joint function.

Used dimexide in gynecological practice in the treatment of infectious and inflammatory diseases of the external female genitalia.

In traumatology dimexide used for various injuries, bruises, sprains, which are accompanied by tissue edema. Dimexidum reduces inflammation and swelling, promotes the resorption of hematomas.

Who should not use Dimexidum and side effects of the drug

Dimexidum has enough contraindications because it actively overcome barriers of skin and mucosal membranes into the blood stream and renders the overall impact on the body.

Dimexidum contraindicated in violation of renal or hepatic function, as these bodies are responsible for the decomposition of Dimexidum to exchange products and removing them from the body. Do not use dimexide as glaucoma Glaucoma - a perspective possible blindness   (elevated intraocular pressure), cataract Cataracts - how to solve the problem completely? , Coronary heart disease, atherosclerosis, pregnancy, breast- Breastfeeding - a personal choice   feeding before the age of 15 and after 60 and hypersensitivity to the drug the patient.

The caution should be applied dimexide together with other drugs, both general and local action as dimexide may enhance their effects, including side effects. But at the same time, the combination with the outer Dimexidum drugs, which include antibiotics, NSAIDs and heparin quite acceptable.

Side effects Dimexidum known allergic reactions and irritation of the skin and mucous membranes, which are accompanied by dry skin and itching. Occasionally there are side effects such as hypersensitive smell Dimexidum and bronchospasm.

Dimexidum - a drug that can help many patients.

Galina Romanenko