- Cytology - insight into the secrets of cells
- History, types, research
History of Discoveries
The development of cytology is historically associated with the creation and improvement of the microscope. But the concept of "cell" was used before the invention of the microscope, the English scientist Hooke, who described the cellular structure of a number of plant tissues. After the discovery of the microscope observations of Hooke were confirmed by other scientists.
Cytology - the science of the structure, function and development of animal and plant cells, as well as single-celled organisms and bacteria. Cytological studies are essential for the diagnosis of human and animal diseases.
The concept of the cell as a structural unit of the body began to form in the first half of the XIX century. At the same time, scientists have found in the cell nucleus, the nucleoli in the nuclei of plant cells and cell division was first observed. Methods have been developed color and enlightenment cell preparations. And in 1839 T.Shvann formulated the cell theory, in which the cell is regarded as the foundation of the structure, functioning and development of animals and plants.
An important stage in the development of cytology was the creation of a German pathologist R.Virhovom doctrine of cellular pathology. He regarded the cell as a material substratum of diseases that attracted them to the study of other doctors and allowed us to study the cell in more detail. It was found that the cell is a complex multicomponent system, open the chromosome, and more, resulting in a cytology by the end of the XIX century became an independent section of biology.
A great influence on the development of cytology was open Austrian biologist Mendel laws inheritance of traits, which led to the creation of the chromosomal theory of heredity and the formation of a new direction in cytology cytogenetics. In the first half of the XX century begins to emerge functional role of intracellular structures, in particular, it was first formulated idea of chromosomes as carriers of molecules of heredity.
In the middle of the XX century there was an electron microscope, and many have been studied as yet unknown properties of the cells. From a theoretical science modern cytology turned into applied science, which is not the last place is occupied by medical research.
Forms and directions of Cytology
There are a total privacy and cytology. General cytology and cell biology studies are common to most types of cell structures, their function, metabolism
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, Damage response, a variety of pathological changes, regenerative processes and adaptation to environmental conditions. Private cytology examines the characteristics of certain types of cells due to their specialization (in multicellular organisms) or adaptation (habituation) to the environment (in protozoa and bacteria).
Currently, there are six main areas of Cytology:
- cytomorphology - studying the structural features of the cell;
- cytophysiology - studying cellular activity as a single living system functioning and interaction of intracellular structures;
- cytochemistry - explores the chemical composition of the cell and its individual components in health and changes therein;
- tsitoekologiya - examines the response of cells to the effects of environmental factors and mechanisms of adaptation;
- cytopathology - studying disease processes in the cell and is divided into viral cytopathology (effect on cell virus) tsitofarmakologiyu (exposing the cell to drugs), cancer cytology (the change in tumor cells), space cytology (the study of the behavior of cells in space flight) and etc.
Cytological studies
Cytological studies - this study with a microscope structural features of the cell, the cell structure of organs, tissues, body fluids of humans and animals in health and in various diseases.
Cytological research techniques used in medicine, largely coincide with the histological studies (the study of tissue taken from the patient's body), but differ in that cytology requires a small amount of biological material, and he investigated without prior training and special equipment, just under the microscope . Cytological studies conducted in the case when a biopsy is impossible or undesirable (for example, when examining a patient in a clinic).
With cytological studies assess the condition of the tissues covering the body (skin and mucous membranes - of the tissue may form cancer), hormonal activity of women, the degree of destruction of tumor cells in the treatment of malignant diseases, the healing process and other processes.
The nature and method of producing the material for the research depends on which organ or tissue is amazed:
- skin diseases - it scrapings and prints fabrics;
- in diseases of the thyroid and mammary glands of the blood - punctate lesions of the sites;
- in diseases of the central nervous system - the cerebrospinal fluid;
- lung disease - mucus and so on.
Cytology - a modern rapidly developing science that is widely used in medical practice.
Galina Romanenko