- Glomerulonephritis - a severe infection of the kidneys
- Causes
Causes
Glomerulonephritis is infectious and allergic inflammation of the bilateral renal tissue. It can be acute or chronic.
The immediate cause of the disease is usually an infection. Most often this is a beta-hemolytic streptococcus twelfth type. Glomerulonephritis can start after a sore throat
Angina - is it worth it to carry "on their feet"?
On the background of chronic tonsillitis
Chronic tonsillitis - inflammation of the tonsils
and other inflammatory and infectious diseases.
Glomerulonephritis may have infectious origin, cause it might be the introduction of vaccines, serums, various medications, pollen and insect venom.
Factors contributing to the development of glomerulonephritis are hypothermia, especially at high humidity. This gives rise to the so-called "trench" Jade: cooling causes the disorder of blood supply to the kidneys and affect the course of immunological reactions.
The mechanism of development
After exposure to infection or other factors (eg, vaccines) after some time (long enough) in a patient's blood develop antibodies to infectious agents and to their own kidney tissue. Gluing antigens (bacteria or kidney tissue), antibodies form antigen-antibody complexes, which are precipitated and deposited on the walls of the renal vessels, as it is filtered and the kidneys excrete harmful substances. There inflammation and destruction (necrosis) of the walls of blood vessels in the kidneys (glomeruli responsible for filtering the blood). All this leads to damage of renal tissue and renal dysfunction.
How is acute glomerulonephritis
Manifestations of acute glomerulonephritis may be very different from terms to almost imperceptible. Usually the disease begins with general weakness, thirst, and a very small amount of urine. Acute glomerulonephritis is characterized by three main features: the changes in the urine, high blood pressure and edema.
Changes in urine - a sign of acute inflammation of the kidney tissue. The patient has pain in the lumbar region on both sides, increased body temperature, a small amount of urine that the admixture of blood gets the color "meat slops". The urine is also found large amounts of protein and cells characteristic of inflammation of the kidney (hyaline, granular, erythrocyte cylinders, renal epithelium). In the blood - signs of inflammation (increased white blood cell count, accelerated erythrocyte sedimentation rate), as well as signs of impaired kidney function - increase of residual nitrogen and its components, such as urea and creatinine
Creatinine - will talk about the work of the kidneys
.
Increased blood pressure is observed in the majority of patients, it is up to 180/120 mm Hg. Art. Against this background, possible development of congestive heart failure with pulmonary edema, as well as changes in the brain.
Swelling in glomerulonephritis have the following characteristics: they are "pale", located on the face, appear in the morning. In severe cases, swelling may spread to the whole body, chest and abdomen. The increase in body weight due to swelling can be very large (up to 20 kg).
Subacute or rapidly progressive glomerulonephritis
Rapidly progressive glomerulonephritis characterized by a subacute, rapidly growing changes in the urine, swelling and progressive increase in blood pressure. In just a few weeks or months developing a complete loss of kidney function.
Developing the disease as acute glomerulonephritis, but sometimes there is a gradual start. Quickly complications appear in the form of changes in the retinal vessels, even blindness, renal failure. Without adequate treatment, the patients die within a year from kidney failure.
Chronic glomerulonephritis
The disease is characterized by progressive loss of renal tissue, renal scarring, reduced kidney function and the development of hypertension and death (without treatment) of chronic renal failure
Chronic renal failure - what to do and how to be?
.
Chronic glomerulonephritis can occur Private (only changes in the urine), manifested swelling or high blood pressure. But with all these forms of the disease are always suffering kidney function.
Treatment of glomerulonephritis
Acute exacerbation of chronic glomerulonephritis and glomerulonephritis treated only in a hospital. At the same time the patient must comply with strict bed rest and salt-free, reduced-protein diet.
To reduce the activity of the immune prescribers who are able to oppress. Since this disease is increased blood clotting, lowering its appointed agents (anticoagulants). Apply anti-inflammatory, decongestant and lowers blood pressure agents. One method of treating glomerulonephritis is the purification of the blood by means hemosorption and plasmapheresis.
After full cure the patient for a long time your doctor should be observed.
Prevention of glomerulonephritis - a timely treatment of throat infections and hardening of the body. It is also important to take into account individual intolerance of medicines, food and other possible allergens.